A pharmaceutical company user's perspective on the potential of high content screening in drug discovery.
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[1] John Hallam,et al. Artificial intelligence and robotics in high throughput post-genomics. , 2005, Drug discovery today.
[2] Thomas Tuschl,et al. Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing. , 2003, Antisense & nucleic acid drug development.
[3] Christine C. Hudson,et al. TRANSFLUOR® Provides a Universal Cell-Based Assay for Screening G-Protein–Coupled Receptors , 2005 .
[4] Thomas Kost,et al. BacMam recombinant baculoviruses in G protein-coupled receptor drug discovery. , 2004, Receptors & channels.
[5] M. Fenech. In vitro micronucleus technique to predict chemosensitivity. , 2005, Methods in molecular medicine.
[6] Hubert C Chen,et al. Determination of adipocyte size by computer image analysis. , 2002, Journal of lipid research.
[7] D. L. Taylor,et al. High content screening applied to large-scale cell biology. , 2004, Trends in biotechnology.
[8] Ahlberg. Visual exploration of HTS databases: bridging the gap between chemistry and biology. , 1999, Drug discovery today.
[9] Thomas D. Y. Chung,et al. A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays , 1999, Journal of biomolecular screening.
[10] M. Caron,et al. Molecular mechanisms of G protein-coupled receptor signaling: role of G protein-coupled receptor kinases and arrestins in receptor desensitization and resensitization. , 1997, Receptors & channels.