1,4-Dihydronaphthoquinones as water-soluble inhibitors of 5-lipoxygenase.

[1]  M. K. Bach,et al.  1,4-Dihydronaphthoquinones, hydroindoloquinones, benzofurans, and benzothiophenes as inhibitors of 5-lipoxygenase. Synthesis and structure-activity studies. , 1990, Journal of medicinal chemistry.

[2]  H. G. Johnson,et al.  Activity of a novel hydroquinone inhibitor of leukotriene synthesis (U-66,858) in the rhesus monkey Ascaris reactor. , 1988, International archives of allergy and applied immunology.

[3]  P. Ward,et al.  Eicosanoids are involved in the permeability changes but not the pulmonary hypertension after systemic activation of complement. , 1988, Laboratory investigation; a journal of technical methods and pathology.

[4]  M. Suzuki,et al.  5-lipoxygenase inhibitor (AA-861) attenuates neutrophil-mediated oxidative stress on the venular endothelium in endotoxemia. , 1988, Journal of clinical & laboratory immunology.

[5]  S. Galli,et al.  Experiments on the mode of action of piriprost (U-60,257), an inhibitor of leukotriene formation in cloned mouse mast cells and in rat basophil leukemia cells. , 1987, Biochemical pharmacology.

[6]  S. Sciortino,et al.  Substituted arylmethyl phenyl ethers. 1. A novel series of 5-lipoxygenase inhibitors and leukotriene antagonists. , 1987, Journal of medicinal chemistry.

[7]  R. Schaub,et al.  Renal microthrombosis following endotoxin infusion may be mediated by lipoxygenase products. , 1987, Circulatory shock.

[8]  S. Rapoport,et al.  Enzymology and physiology of reticulocyte lipoxygenase: comparison with other lipoxygenases. , 2006, Advances in enzymology and related areas of molecular biology.

[9]  R. Schaub,et al.  Leukocyte mediated vein injury and thrombosis is reduced by a lipoxygenase inhibitor. , 1986, Experimental and molecular pathology.

[10]  H. Mita,et al.  Effect of AA‐861, a 5‐Lipoxygenase Inhibitor, on Leukotriene Synthesis in Human Polymorphonuclear Leukocytes and on Cyclooxygenase and 12‐Lipoxygenase Activities in Human Platelets , 1986, Allergy.

[11]  S. Yamamoto,et al.  Arachidonate 5-lipoxygenase and its new inhibitors. , 1984, The Journal of allergy and clinical immunology.

[12]  R. Schaub,et al.  Early events in the formation of a venous thrombus following local trauma and stasis. , 1984, Laboratory investigation; a journal of technical methods and pathology.

[13]  J. R. Pfister,et al.  Synthesis of three potential inhibitors of leukotriene biosynthesis. , 1983, Journal of medicinal chemistry.

[14]  C. A. Bunton,et al.  Dephosphorylation in cationic micelles and microemulsions. Effects of added alcohols , 1983 .

[15]  E. Corey,et al.  Irreversible inhibition of the leukotriene pathway by 4,5-dehydroarachidonic acid , 1983 .

[16]  H. Sarau,et al.  Dimethyleicosatrienoic acids: Inhibitors of the 5-lipoxygenase enzyme , 1983 .

[17]  R. Bryant,et al.  Regulation of leukocyte and platelet lipoxygenases by hydroxyeicosanoids. , 1982, Biochemical pharmacology.

[18]  D. Sok,et al.  Inhibition of leukotriene biosynthesis by acetylenic analogs , 1982 .

[19]  K. Nicolaou,et al.  Selective inhibition of 5‐lipoxygenase by 5,6‐methanoleukotriene A4, a stable analogue of leukotriene A4 , 1982, FEBS letters.

[20]  M. K. Bach,et al.  6,9-deepoxy-6,9,-(phenylimino)-delta 6,8-prostaglandin I1, (U-60,257), a new inhibitor of leukotriene C and D synthesis: in vitro studies. , 1982, Prostaglandins.

[21]  E. Corey,et al.  Short, stereocontrolled syntheses of irreversible eicosanoid biosynthesis inhibitors. 5,6- , 8,9- , and 11,12-dehydroarachidonic acid , 1982 .

[22]  A. Ford-hutchinson.  Leukotriene B4 and Neutrophil Function: A Review 1 , 1981, Journal of the Royal Society of Medicine.

[23]  Bengt Samuelsson,et al.  Leukotrienes are potent constrictors of human bronchi , 1980, Nature.

[24]  K. H. Dötz,et al.  Vinylketene, II. Stabile silylsubstituierte Vinylketene , 1980 .

[25]  E. Corey,et al.  Synthesis of three potential inhibitors of the biosynthesis of leukotrienes A–E , 1980 .

[26]  K. H. Dötz,et al.  Reaktionen von Komplexliganden, XII. Templat‐Reaktionen an Chrom(0): Stereoselektive Synthese kondensierter aromatischer Liganden aus Pentacarbonyl‐Carben‐Chrom‐Komplexen und Alkinen , 1978 .

[27]  E. Fischer,et al.  Übergangsmetall-Carben-Komplexe, IV. Addition von Isonitrilen an Methylmethoxycarben-pentacarbonyl-chrom(0) , 1968 .