Reactivity of RPCF test in leprosy compared with other syphilis tests.

LEPROSY stands high on the list of clinical J entities known to produce biologic falsepositive reactions with the conventional sero¬ logic tests for syphilis. Of the many pro¬ cedures which have been used for the differen¬ tiation of the BFP reactor from the syphilitic reactor the Treponema pallidwn immobilization (TPI) test has been considered to be the most reliable. The data presented in this paper in¬ dicate that in persons with leprosy, the Reiter protein complement fixation (RPCF) test is as reliable as the TPI test in differentiating syphilitic and biologic false-positive reactors. The several serologic tests for syphilis em¬ ploying lipoidal antigens are known to produce varying degrees of biologic false-positive re-

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