HIV-1 Gag co-opts a cellular complex containing DDX 6 , a helicase that facilitates capsid assembly

The Rockefeller University Press $30.00 J. Cell Biol. Vol. 198 No. 3 439–456 www.jcb.org/cgi/doi/10.1083/jcb.201111012 JCB 439 Correspondence to Jaisri R. Lingappa: jais@u.washington.edu Abbreviations used in this paper: AI, assembly intermediate; gRNA, genomic RNA; HFV, human foamy virus; HMW, high molecular weight; IEM, immunoelectron microscopy; IP, immunoprecipitation; KD, knockdown; LZ, leucine zipper; miRNA, microRNA; PB, processing body; PBP, PB protein; PM, plasma membrane; RCG, region of clustered Gag; RNP, ribonucleoprotein; VLP, viruslike particle; VS, velocity sedimentation; WB, Western blot; WT, wild type. Introduction

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