The human ATP-binding cassette (ABC) transporter superfamily.
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[1] C. Scagnolari,et al. Impaired 2',3'-dideoxy-3'-thiacytidine accumulation in T-lymphoblastoid cells as a mechanism of acquired resistance independent of multidrug resistant protein 4 with a possible role for ATP-binding cassette C11. , 2002, The Biochemical journal.
[2] A. Zwinderman,et al. Frequent Mutation in the ABCC6 Gene (R1141X) Is Associated With a Strong Increase in the Prevalence of Coronary Artery Disease , 2002, Circulation.
[3] T. Langmann,et al. Mutations in the human ATP‐binding cassette transporters ABCG5 and ABCG8 in sitosterolemia , 2002, Human mutation.
[4] H. Brewer,et al. Comparative genome analysis of potential regulatory elements in the ABCG5-ABCG8 gene cluster. , 2002, Biochemical and biophysical research communications.
[5] T. Langmann,et al. Molecular structure of a novel cholesterol-responsive A subclass ABC transporter, ABCA9. , 2002, Biochemical and biophysical research communications.
[6] B. McManus,et al. Increased ABCA1 activity protects against atherosclerosis. , 2002, The Journal of clinical investigation.
[7] M. Emi,et al. Clinical variant of Tangier disease in Japan: mutation of the ABCA1 gene in hypoalphalipoproteinemia with corneal lipidosis , 2002, Journal of Human Genetics.
[8] T. Ishikawa,et al. Molecular and cytogenetic characterization of the mouse ATP-binding cassette transporter Abcg4. , 2002, Gene.
[9] J. Pelletier,et al. Nucleotide binding and nucleotide hydrolysis properties of the ABC transporter MRP6 (ABCC6). , 2002, Biochemistry.
[10] A. Fisher,et al. Identification of LBM180, a Lamellar Body Limiting Membrane Protein of Alveolar Type II Cells, as the ABC Transporter Protein ABCA3* , 2002, The Journal of Biological Chemistry.
[11] D. Keppler,et al. Radixin deficiency causes conjugated hyperbilirubinemia with loss of Mrp2 from bile canalicular membranes , 2002, Nature Genetics.
[12] H. Moser,et al. Contiguous deletion of the X-linked adrenoleukodystrophy gene (ABCD1) and DXS1357E: a novel neonatal phenotype similar to peroxisomal biogenesis disorders. , 2002, American journal of human genetics.
[13] B. Sarkadi,et al. Loss of ATP-dependent Transport Activity in Pseudoxanthoma Elasticum-associated Mutants of Human ABCC6 (MRP6)* , 2002, The Journal of Biological Chemistry.
[14] S. O'Dea,et al. CFTR gene transfer to lung epithelium--on the trail of a target cell. , 2002, Current gene therapy.
[15] K. Kutsche,et al. Characterization of breakpoint sequences of five rearrangements in L1CAM and ABCD1 (ALD) genes , 2002, Human mutation.
[16] Jonathan C. Cohen,et al. Heritability of plasma noncholesterol sterols and relationship to DNA sequence polymorphism in ABCG5 and ABCG8. , 2002, Journal of lipid research.
[17] M. Schachner,et al. Late onset neurological phenotype of the X-ALD gene inactivation in mice: a mouse model for adrenomyeloneuropathy. , 2002, Human molecular genetics.
[18] K. Faber,et al. Farnesoid X receptor and bile salts are involved in transcriptional regulation of the gene encoding the human bile salt export pump , 2002, Hepatology.
[19] A. Hutchinson,et al. Animal Cytogenetics and Comparative Mapping , 2002 .
[20] C. Lam,et al. Novel donor splice site mutation of ABCG5 gene in sitosterolemia. , 2002, Molecular genetics and metabolism.
[21] K. Roomp,et al. ABCA1 regulatory variants influence coronary artery disease independent of effects on plasma lipid levels , 2002, Clinical genetics.
[22] Bonnie L. Firestein,et al. Identification of a host protein essential for assembly of immature HIV-1 capsids , 2002, Nature.
[23] R. F. Hoyt,et al. The ATP binding cassette transporter A1 (ABCA1) modulates the development of aortic atherosclerosis in C57BL/6 and apoE-knockout mice , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[24] R. Hegele,et al. ABCC6 gene polymorphism associated with variation in plasma lipoproteins , 2001, Journal of Human Genetics.
[25] H. Moser,et al. ABCD1 mutations and the X‐linked adrenoleukodystrophy mutation database: Role in diagnosis and clinical correlations , 2001, Human mutation.
[26] O. Kawanami,et al. ABCA3 is a lamellar body membrane protein in human lung alveolar type II cells1 , 2001, FEBS letters.
[27] G. Szakács,et al. Characterization of the ATPase cycle of human ABCA1: implications for its function as a regulator rather than an active transporter. , 2001, Biochemical and biophysical research communications.
[28] G. Cantor,et al. Ivermectin sensitivity in collies is associated with a deletion mutation of the mdr1 gene. , 2001, Pharmacogenetics.
[29] M. Hayden,et al. Pivotal role of ABCA1 in reverse cholesterol transport influencing HDL levels and susceptibility to atherosclerosis. , 2001, Journal of lipid research.
[30] B. Bartel,et al. The Arabidopsis pxa1 mutant is defective in an ATP-binding cassette transporter-like protein required for peroxisomal fatty acid beta-oxidation. , 2001, Plant physiology.
[31] S. Lorkowski,et al. The human ABCG4 gene is regulated by oxysterols and retinoids in monocyte-derived macrophages. , 2001, Biochemical and biophysical research communications.
[32] T. Langmann,et al. Role of ABCG1 and other ABCG family members in lipid metabolism. , 2001, Journal of lipid research.
[33] S. Terry,et al. A spectrum of ABCC6 mutations is responsible for pseudoxanthoma elasticum. , 2001, American journal of human genetics.
[34] Jonathan C. Cohen,et al. Mutations in ATP‐cassette binding proteins G5 (ABCG5) and G8 (ABCG8) causing sitosterolemia , 2001, Human mutation.
[35] C. Valdivia,et al. Disruption of Sur2-containing KATP channels enhances insulin-stimulated glucose uptake in skeletal muscle , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[36] F. Kuipers,et al. Hepatobiliary cholesterol transport is not impaired in Abca1-null mice lacking HDL , 2001 .
[37] T. Litman,et al. Acquired mutations in the MXR/BCRP/ABCP gene alter substrate specificity in MXR/BCRP/ABCP-overexpressing cells. , 2001, Cancer research.
[38] H. Nakauchi,et al. The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype , 2001, Nature Medicine.
[39] J. Uitto,et al. Identification of ABCC6 pseudogenes on human chromosome 16p: implications for mutation detection in pseudoxanthoma elasticum , 2001, Human Genetics.
[40] A. Pandya,et al. Two genes that map to the STSL locus cause sitosterolemia: genomic structure and spectrum of mutations involving sterolin-1 and sterolin-2, encoded by ABCG5 and ABCG8, respectively. , 2001, American journal of human genetics.
[41] I. Pastan,et al. MRP8, A New Member of ABC Transporter Superfamily, Identified by EST Database Mining and Gene Prediction Program, Is Highly Expressed in Breast Cancer , 2001, Molecular medicine.
[42] A. Hutchinson,et al. Two new genes from the human ATP-binding cassette transporter superfamily, ABCC11 and ABCC12, tandemly duplicated on chromosome 16q12. , 2001, Gene.
[43] D. Birch,et al. Delayed dark-adaptation and lipofuscin accumulation in abcr+/- mice: implications for involvement of ABCR in age-related macular degeneration. , 2001, Investigative ophthalmology & visual science.
[44] L. Schriml,et al. An ATP-binding cassette gene (ABCG5) from the ABCG (White) gene subfamily maps to human chromosome 2p21 in the region of the Sitosterolemia locus , 2001, Cytogenetic and Genome Research.
[45] T. Pineau,et al. Fibrate induction of the adrenoleukodystrophy-related gene (ABCD2): promoter analysis and role of the peroxisome proliferator-activated receptor PPARalpha. , 2001, European journal of biochemistry.
[46] T. Nagase,et al. Human ABCA1 contains a large amino-terminal extracellular domain homologous to an epitope of Sjögren's Syndrome. , 2001, Biochemical and biophysical research communications.
[47] K. Tew,et al. Cloning and characterization of human adenosine 5'-triphosphate-binding cassette, sub-family A, transporter 2 (ABCA2). , 2001, Cancer research.
[48] M. Welsh,et al. Regulation of the Cystic Fibrosis Transmembrane Conductance Regulator Cl− Channel by Its R Domain* , 2001, The Journal of Biological Chemistry.
[49] G. Schmitz,et al. Complete coding sequence, promoter region, and genomic structure of the human ABCA2 gene and evidence for sterol-dependent regulation in macrophages. , 2001, Biochemical and biophysical research communications.
[50] J. V. Moran,et al. Initial sequencing and analysis of the human genome. , 2001, Nature.
[51] C. Ackerley,et al. Targeted inactivation of sister of P-glycoprotein gene (spgp) in mice results in nonprogressive but persistent intrahepatic cholestasis. , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[52] T. Hirabayashi,et al. ATP-Binding Cassette Transporter ABC2/ABCA2 in the Rat Brain: A Novel Mammalian Lysosome-Associated Membrane Protein and a Specific Marker for Oligodendrocytes But Not for Myelin Sheaths , 2001, The Journal of Neuroscience.
[53] A Rzhetsky,et al. The human ATP-binding cassette (ABC) transporter superfamily. , 2001, Journal of lipid research.
[54] G. Szakács,et al. Characterization of the amino-terminal regions in the human multidrug resistance protein (MRP1). , 2000, Journal of cell science.
[55] N. Grishin,et al. Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters. , 2000, Science.
[56] G. Schmitz,et al. Genomic organization of the human cholesterol-responsive ABC transporter ABCA7: tandem linkage with the minor histocompatibility antigen HA-1 gene. , 2000, Biochemical and biophysical research communications.
[57] D. Jäger,et al. The Leukotriene C4 Transporter MRP1 Regulates CCL19 (MIP-3β, ELC)–Dependent Mobilization of Dendritic Cells to Lymph Nodes , 2000, Cell.
[58] Jean-Marc A. Lobaccaro,et al. Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRα and LXRβ , 2000 .
[59] T. Langmann,et al. Genomic organization and characterization of the promoter of the human ATP-binding cassette transporter-G1 (ABCG1) gene. , 2000, Biochimica et biophysica acta.
[60] C. Proud,et al. ABC50 Interacts with Eukaryotic Initiation Factor 2 and Associates with the Ribosome in an ATP-dependent Manner* , 2000, The Journal of Biological Chemistry.
[61] J. Tolmie,et al. Human ABC7 transporter: gene structure and mutation causing X-linked sideroblastic anemia with ataxia with disruption of cytosolic iron-sulfur protein maturation , 2000 .
[62] J. Schellens,et al. Role of breast cancer resistance protein in the bioavailability and fetal penetration of topotecan. , 2000, Journal of the National Cancer Institute.
[63] R. Allikmets. Simple and complex ABCR: genetic predisposition to retinal disease. , 2000, American journal of human genetics.
[64] Eric S. Lander,et al. The common PPARγ Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes , 2000, Nature Genetics.
[65] M. Kool,et al. A family of drug transporters: the multidrug resistance-associated proteins. , 2000, Journal of the National Cancer Institute.
[66] C. Bellanné-Chantelot,et al. Association of a variant in exon 31 of the sulfonylurea receptor 1 (SUR1) gene with type 2 diabetes mellitus in French Caucasians , 2000, Human Genetics.
[67] V. Ling,et al. M‐ABC2, a new human mitochondrial ATP‐binding cassette membrane protein , 2000, FEBS letters.
[68] V. Ling,et al. Characterization of ABCB9, an ATP Binding Cassette Protein Associated with Lysosomes* , 2000, The Journal of Biological Chemistry.
[69] G. Schmitz,et al. Identification of a novel human sterol-sensitive ATP-binding cassette transporter (ABCA7). , 2000, Biochemical and biophysical research communications.
[70] J. Cheng,et al. Complete genomic sequence of the human ABCA1 gene: analysis of the human and mouse ATP-binding cassette A promoter. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[71] F. Baas,et al. Multidrug-resistance protein 5 is a multispecific organic anion transporter able to transport nucleotide analogs. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[72] T. Iwanaga,et al. MTABC3, a Novel Mitochondrial ATP-binding Cassette Protein Involved in Iron Homeostasis* 210 , 2000, The Journal of Biological Chemistry.
[73] M. Kool,et al. Mutations in ABCC6 cause pseudoxanthoma elasticum , 2000, Nature Genetics.
[74] E. Hudson,et al. The multidrug-resistant phenotype associated with overexpression of the new ABC half-transporter, MXR (ABCG2). , 2000, Journal of cell science.
[75] S. Terry,et al. Mutations in a gene encoding an ABC transporter cause pseudoxanthoma elasticum , 2000, Nature Genetics.
[76] A. Lumsden,et al. Mutations of the gene encoding the transmembrane transporter protein ABC-C6 cause pseudoxanthoma elasticum , 2000, Journal of Molecular Medicine.
[77] M. Lebwohl,et al. Pseudoxanthoma elasticum: mutations in the MRP6 gene encoding a transmembrane ATP-binding cassette (ABC) transporter. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[78] P. Duchateau,et al. Analysis of hABC1 gene 5' end: additional peptide sequence, promoter region, and four polymorphisms. , 2000, Biochemical and biophysical research communications.
[79] M. McCarthy,et al. Heterozygous MDR3 missense mutation associated with intrahepatic cholestasis of pregnancy: evidence for a defect in protein trafficking. , 2000, Human molecular genetics.
[80] T. Litman,et al. The product of the ABC half-transporter gene ABCG2 (BCRP/MXR/ABCP) is expressed in the plasma membrane. , 2000, Biochemical and biophysical research communications.
[81] C. Gabel,et al. High density lipoprotein deficiency and foam cell accumulation in mice with targeted disruption of ATP-binding cassette transporter-1. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[82] L. Aguilar-Bryan,et al. Sur1 Knockout Mice , 2000, The Journal of Biological Chemistry.
[83] U. Brinkmann,et al. Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[84] P. Meier,et al. Transport function and hepatocellular localization of mrp6 in rat liver. , 2000, Molecular pharmacology.
[85] L. Schriml,et al. Identification of 18 mouse ABC genes and characterization of the ABC superfamily in Mus musculus. , 2000, Genomics.
[86] Eugene W. Myers,et al. A whole-genome assembly of Drosophila. , 2000, Science.
[87] T. Langmann,et al. Transport of lipids from Golgi to plasma membrane is defective in Tangier disease patients and Abc1-deficient mice , 2000, Nature Genetics.
[88] G. Schmitz,et al. ABCG1 (ABC8), the human homolog of the Drosophila white gene, is a regulator of macrophage cholesterol and phospholipid transport. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[89] M. Luciani,et al. The ABCA subclass of mammalian transporters. , 1999, Biochimica et biophysica acta.
[90] B. Sarkadi,et al. An inventory of the human ABC proteins. , 1999, Biochimica et biophysica acta.
[91] L. Bain,et al. Expression of multidrug resistance protein-3 (multispecific organic anion transporter-D) in human embryonic kidney 293 cells confers resistance to anticancer agents. , 1999, Cancer research.
[92] Y. Pommier,et al. Camptothecin resistance: role of the ATP-binding cassette (ABC), mitoxantrone-resistance half-transporter (MXR), and potential for glucuronidation in MXR-expressing cells. , 1999, Cancer research.
[93] T. Litman,et al. Reversal of resistance by GF120918 in cell lines expressing the ABC half-transporter, MXR. , 1999, Cancer letters.
[94] P. Denéfle,et al. Human ATP-binding cassette transporter 1 (ABC1): genomic organization and identification of the genetic defect in the original Tangier disease kindred. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[95] C. Sensen,et al. Mutations in the ABC 1 gene in familial HDL deficiency with defective cholesterol efflux , 1999, The Lancet.
[96] J. Wijnholds,et al. The mouse Bcrp1/Mxr/Abcp gene: amplification and overexpression in cell lines selected for resistance to topotecan, mitoxantrone, or doxorubicin. , 1999, Cancer research.
[97] J. Schuetz,et al. MRP4: A previously unidentified factor in resistance to nucleoside-based antiviral drugs , 1999, Nature Medicine.
[98] S. Young,et al. The ABCs of cholesterol efflux , 1999, Nature Genetics.
[99] T. Langmann,et al. The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease , 1999, Nature Genetics.
[100] J. Piette,et al. Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1 , 1999, Nature Genetics.
[101] C. Sensen,et al. Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency , 1999, Nature Genetics.
[102] D. Birch,et al. Insights into the Function of Rim Protein in Photoreceptors and Etiology of Stargardt's Disease from the Phenotype in abcr Knockout Mice , 1999, Cell.
[103] G. Peters,et al. MRP3, an organic anion transporter able to transport anti-cancer drugs. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[104] A. Munnich,et al. Mutations of the retinal specific ATP binding transporter gene (ABCR) in a single family segregating both autosomal recessive retinitis pigmentosa RP19 and Stargardt disease: evidence of clinical heterogeneity at this locus , 1999, Journal of medical genetics.
[105] J. Riordan. Cystic fibrosis as a disease of misprocessing of the cystic fibrosis transmembrane conductance regulator glycoprotein. , 1999, American journal of human genetics.
[106] J. Testa,et al. Characterization of MOAT-C and MOAT-D, New Members of the MRP/cMOAT Subfamily of Transporter Proteins , 1999 .
[107] D. Keppler,et al. Drug resistance and ATP-dependent conjugate transport mediated by the apical multidrug resistance protein, MRP2, permanently expressed in human and canine cells. , 1999, Molecular pharmacology.
[108] A. Holzinger,et al. Adrenoleukodystrophy-related protein can compensate functionally for adrenoleukodystrophy protein deficiency (X-ALD): implications for therapy. , 1999, Human molecular genetics.
[109] T. Langmann,et al. Molecular cloning of the human ATP-binding cassette transporter 1 (hABC1): evidence for sterol-dependent regulation in macrophages. , 1999, Biochemical and biophysical research communications.
[110] A. Hutchinson,et al. Mutation of a Putative Mitochondrial Iron Transporter Gene (ABC7) in X-Linked Sideroblastic Anemia and Ataxia (XLSA/A) , 1999, Human molecular genetics.
[111] H. Takano,et al. Multidrug resistance-associated protein subfamily transporters and drug resistance. , 1999, Anti-cancer drug design.
[112] S Uebel,et al. Specificity of the proteasome and the TAP transporter. , 1999, Current opinion in immunology.
[113] J. Nathans,et al. Retinal Stimulates ATP Hydrolysis by Purified and Reconstituted ABCR, the Photoreceptor-specific ATP-binding Cassette Transporter Responsible for Stargardt Disease* , 1999, The Journal of Biological Chemistry.
[114] M Dietel,et al. Atypical multidrug resistance: breast cancer resistance protein messenger RNA expression in mitoxantrone-selected cell lines. , 1999, Journal of the National Cancer Institute.
[115] S. Sakisaka,et al. [Genomic structure of the canalicular multispecific organic anion-transporter gene (MRP2/cMOAT) and mutations in the ATP-binding-cassette region in Dubin-Johnson syndrome]. , 1999, Fukuoka igaku zasshi = Hukuoka acta medica.
[116] A. Plebani,et al. HLA class I deficiencies due to mutations in subunit 1 of the peptide transporter TAP1. , 1999, The Journal of clinical investigation.
[117] R. Boucher,et al. Status of gene therapy for cystic fibrosis lung disease. , 1999, The Journal of clinical investigation.
[118] J. Wine. The genesis of cystic fibrosis lung disease. , 1999, The Journal of clinical investigation.
[119] M. Hadchouel,et al. Heterozygous non-sense mutation of the MDR3 gene in familial intrahepatic cholestasis of pregnancy , 1999, The Lancet.
[120] V. Ling,et al. Identification and characterization of a mammalian mitochondrial ATP-binding cassette membrane protein. , 1999, Journal of molecular biology.
[121] L. Doyle,et al. A multidrug resistance transporter from human MCF-7 breast cancer cells. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[122] R. Lill,et al. Identification of a human mitochondrial ABC transporter, the functional orthologue of yeast Atm1p , 1998, FEBS letters.
[123] Li-Wei Hung,et al. Crystal structure of the ATP-binding subunit of an ABC transporter , 1998, Nature.
[124] S. Rabindran,et al. Reversal of a novel multidrug resistance mechanism in human colon carcinoma cells by fumitremorgin C. , 1998, Cancer research.
[125] Vincenzo,et al. A human placenta-specific ATP-binding cassette gene (ABCP) on chromosome 4q22 that is involved in multidrug resistance. , 1998, Cancer research.
[126] I. Pastan,et al. Contribution to substrate specificity and transport of nonconserved residues in transmembrane domain 12 of human P-glycoprotein. , 1998, Biochemistry.
[127] Richard J. Thompson,et al. A gene encoding a liver-specific ABC transporter is mutated in progressive familial intrahepatic cholestasis , 1998, Nature Genetics.
[128] S. Cole,et al. Multidrug resistance mediated by the ATP‐binding cassette transporter protein MRP , 1998, BioEssays : news and reviews in molecular, cellular and developmental biology.
[129] M. Luciani,et al. ABC1, the mammalian homologue of the engulfment gene ced-7, is required during phagocytosis of both necrotic and apoptotic cells. , 1998, Biochemical Society transactions.
[130] J. Mandel,et al. Exon organisation of the mouse gene encoding the Adrenoleukodystrophy related protein (ALDRP) , 1998, European Journal of Human Genetics.
[131] M. Knowles,et al. Relation between mutations of the cystic fibrosis gene and idiopathic pancreatitis. , 1998, The New England journal of medicine.
[132] P. O'Connell,et al. Variant in sulfonylurea receptor-1 gene is associated with high insulin concentrations in non-diabetic Mexican Americans: SUR-1 gene variant and hyperinsulinemia , 1998, Human Genetics.
[133] M. Polymeropoulos,et al. Mapping a gene involved in regulating dietary cholesterol absorption. The sitosterolemia locus is found at chromosome 2p21. , 1998, The Journal of clinical investigation.
[134] M. Androlewicz,et al. Herpes Simplex Virus Inhibitor ICP47 Destabilizes the Transporter Associated with Antigen Processing (TAP) Heterodimer* , 1998, The Journal of Biological Chemistry.
[135] D. Bell,et al. Isolation of MOAT-B, a widely expressed multidrug resistance-associated protein/canalicular multispecific organic anion transporter-related transporter. , 1998, Cancer research.
[136] J. Slot,et al. Generation and characterization of monoclonal antibodies to alveolar type II cell lamellar body membrane. , 1998, The American journal of physiology.
[137] H. Horvitz,et al. The C. elegans Cell Corpse Engulfment Gene ced-7 Encodes a Protein Similar to ABC Transporters , 1998, Cell.
[138] R. Steinman,et al. A physiologic function for p-glycoprotein (MDR-1) during the migration of dendritic cells from skin via afferent lymphatic vessels. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[139] M. Evans,et al. Salmonella typhi uses CFTR to enter intestinal epithelial cells , 1998, Nature.
[140] P. Meier,et al. The Sister of P-glycoprotein Represents the Canalicular Bile Salt Export Pump of Mammalian Liver* , 1998, The Journal of Biological Chemistry.
[141] P. Lichtner,et al. Genomic organization and chromosomal localization of the human peroxisomal membrane protein‐1‐like protein (PXMP1‐L) gene encoding a peroxisomal ABC transporter 1 , 1998, FEBS letters.
[142] D. Bell,et al. Amplification of the ATP-binding cassette 2 transporter gene is functionally linked with enhanced efflux of estramustine in ovarian carcinoma cells. , 1998, Cancer research.
[143] K Rohrschneider,et al. Autosomal recessive retinitis pigmentosa and cone-rod dystrophy caused by splice site mutations in the Stargardt's disease gene ABCR. , 1998, Human molecular genetics.
[144] K. Kohno,et al. Mutations in the Canalicular Multispecific Organic Anion Transporter (cMOAT) Gene, a Novel ABC Transporter, in Patients with Hyperbilirubinemia II/Dubin-Johnson Syndrome , 1998 .
[145] P. Bosma,et al. Mutations in the MDR3 gene cause progressive familial intrahepatic cholestasis. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[146] B. Guiard,et al. The ABC transporter Atm1p is required for mitochondrial iron homeostasis , 1997, FEBS letters.
[147] K. Nave,et al. Targeted inactivation of the X‐linked adrenoleukodystrophy gene in mice , 1997, Journal of neuroscience research.
[148] R. Flavell,et al. Disruption of the murine MRP (multidrug resistance protein) gene leads to increased sensitivity to etoposide (VP-16) and increased levels of glutathione. , 1997, Cancer research.
[149] Jos H. Beijnen,et al. Increased sensitivity to anticancer drugs and decreased inflammatory response in mice lacking the multidrug resistance-associated protein , 1997, Nature Medicine.
[150] H. Tabak,et al. Transport of activated fatty acids by the peroxisomal ATP-binding-cassette transporter Pxa2 in a semi-intact yeast cell system. , 1997, European journal of biochemistry.
[151] D. Valle,et al. Identification of a fourth half ABC transporter in the human peroxisomal membrane. , 1997, Human molecular genetics.
[152] Paul S. Bernstein,et al. Mutation of the Stargardt Disease Gene (ABCR) in Age-Related Macular Degeneration , 1997 .
[153] S Uebel,et al. Recognition principle of the TAP transporter disclosed by combinatorial peptide libraries. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[154] M. Kool,et al. Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines. , 1997, Cancer research.
[155] A. Holzinger,et al. Primary structure of human PMP69, a putative peroxisomal ABC-transporter. , 1997, Biochemical and biophysical research communications.
[156] M. Marton,et al. Evidence that GCN1 and GCN20, translational regulators of GCN4, function on elongating ribosomes in activation of eIF2alpha kinase GCN2 , 1997, Molecular and cellular biology.
[157] M. Nei,et al. Evolution by the birth-and-death process in multigene families of the vertebrate immune system. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[158] G. Travis,et al. The photoreceptor rim protein is an ABC transporter encoded by the gene for recessive Stargardt's disease (ABCR) , 1997, FEBS letters.
[159] C. P. Morris,et al. Absence of mutations raises doubts about the role of the 70-kD peroxisomal membrane protein in Zellweger syndrome. , 1997, American journal of human genetics.
[160] R. F. Cook,et al. The Active Site of ICP47, a Herpes Simplex Virus–encoded Inhibitor of the Major Histocompatibility Complex (MHC)-encoded Peptide Transporter Associated with Antigen Processing (TAP), Maps to the NH2-terminal 35 Residues , 1997, The Journal of experimental medicine.
[161] P. Borst,et al. Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug-transporting) P-glycoproteins. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[162] J. Lupski,et al. A photoreceptor cell-specific ATP-binding transporter gene (ABCR) is mutated in recessive Starqardt macular dystrophy , 1997, Nature Genetics.
[163] G. Gyapay,et al. Chromosomal Localization of the Adrenoleukodystrophy-Related Gene in Man and Mice , 1997, European journal of human genetics : EJHG.
[164] André Goffeau,et al. Complete inventory of the yeast ABC proteins , 1997, Nature Genetics.
[165] J. Fletcher,et al. Isolation and characterization of a mammalian homolog of the Drosophila white gene. , 1997, Gene.
[166] Piet Borst,et al. MDR1 P-Glycoprotein Is a Lipid Translocase of Broad Specificity, While MDR3 P-Glycoprotein Specifically Translocates Phosphatidylcholine , 1996, Cell.
[167] D. Valle,et al. A Saccharomyces cerevisiae homolog of the human adrenoleukodystrophy transporter is a heterodimer of two half ATP-binding cassette transporters. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[168] A. Hutchinson,et al. Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database. , 1996, Human molecular genetics.
[169] N. Klugbauer,et al. Primary structure of a novel ABC transporter with a chromosomal localization on the band encoding the multidrug resistance‐associated protein , 1996, FEBS letters.
[170] A. Chakravarti,et al. Cloning of the cDNA for a human homologue of the Drosophila white gene and mapping to chromosome 21q22.3. , 1996, American journal of human genetics.
[171] R. Tampé,et al. A functionally defective allele of TAP1 results in loss of MHC class I antigen presentation in a human lung cancer , 1996, Nature Genetics.
[172] M. Hadchouel,et al. Defect of multidrug‐resistance 3 gene expression in a subtype of progressive familial intrahepatic cholestasis , 1996, Hepatology.
[173] S. Diriong,et al. Localization of the ribonuclease L inhibitor gene (RNS4I), a new member of the interferon-regulated 2-5A pathway, to 4q31 by fluorescence in situ hybridization. , 1996, Genomics.
[174] F. Galibert,et al. Chromosomal localization and expression pattern of the RNase L inhibitor gene , 1996, FEBS letters.
[175] P. Bosma,et al. Congenital Jaundice in Rats with a Mutation in a Multidrug Resistance-Associated Protein Gene , 1996, Science.
[176] J. Mandel,et al. A close relative of the adrenoleukodystrophy (ALD) gene codes for a peroxisomal protein with a specific expression pattern. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[177] R. Allikmets,et al. Evolution of ATP-binding cassette transporter genes. , 1995, Current opinion in genetics & development.
[178] H. Morreau,et al. A mouse model for the cystic fibrosis delta F508 mutation. , 1995, The EMBO journal.
[179] C. Bisbal,et al. Cloning and Characterization of a RNase L Inhibitor. , 1995, The Journal of Biological Chemistry.
[180] V. Ling,et al. Identification of a sister gene to P-glycoprotein. , 1995, Cancer research.
[181] J. Bryan,et al. Mutations in the sulfonylurea receptor gene in familial persistent hyperinsulinemic hypoglycemia of infancy. , 1995, Science.
[182] P. Pignatti,et al. Increased incidence of cystic fibrosis gene mutations in adults with disseminated bronchiectasis. , 1995, Human molecular genetics.
[183] L. Tsui,et al. The cystic fibrosis transmembrane conductance regulator gene. , 1995, American journal of respiratory and critical care medicine.
[184] A. Attie,et al. Hypercatabolism of lipoprotein-free apolipoprotein A-I in HDL-deficient mutant chickens. , 1994, Arteriosclerosis and thrombosis : a journal of vascular biology.
[185] G. M. Wilson,et al. Pharmacological characterization of multidrug resistant MRP-transfected human tumor cells. , 1994, Cancer research.
[186] D. Keppler,et al. The MRP gene encodes an ATP-dependent export pump for leukotriene C4 and structurally related conjugates. , 1994, The Journal of biological chemistry.
[187] K. Beckman,et al. Very long chain fatty acids in X‐linked adrenoleukodystrophy brain after treatment with Lorenzo's oil , 1994, Annals of neurology.
[188] F. Baas,et al. The human multidrug resistance-associated protein MRP is a plasma membrane drug-efflux pump. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[189] P. Quinton. Human Genetics: What is good about cystic fibrosis? , 1994, Current Biology.
[190] J. Salamero,et al. Homozygous human TAP peptide transporter mutation in HLA class I deficiency. , 1994, Science.
[191] P. Gros,et al. Phosphatidylcholine translocase: A physiological role for the mdr2 gene , 1994, Cell.
[192] J. H. Beijnen,et al. Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs , 1994, Cell.
[193] D. Andrews,et al. A cytosolic herpes simplex virus protein inhibits antigen presentation to CD8+ T lymphocytes , 1994, Cell.
[194] M. Nei,et al. Divergent evolution and evolution by the birth-and-death process in the immunoglobulin VH gene family. , 1994, Molecular biology and evolution.
[195] F. Denizot,et al. Cloning of two novel ABC transporters mapping on human chromosome 9. , 1994, Genomics.
[196] A. McMichael,et al. HLA class I molecules are not transported to the cell surface in cells infected with herpes simplex virus types 1 and 2. , 1994, Journal of immunology.
[197] A. Montag,et al. Histologic Pathology of the Liver in Progressive Familial Intrahepatic Cholestasis , 1994, Journal of pediatric gastroenterology and nutrition.
[198] P. Borst,et al. Homozygous disruption of the murine MDR2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease , 1993, Cell.
[199] P. Cresswell,et al. Evidence that transporters associated with antigen processing translocate a major histocompatibility complex class I-binding peptide into the endoplasmic reticulum in an ATP-dependent manner. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[200] S. Tonegawa,et al. TAP1-dependent peptide translocation in vitro is ATP dependent and peptide selective , 1993, Cell.
[201] R. Boucher,et al. CFTR and outward rectifying chloride channels are distinct proteins with a regulatory relationship , 1993, Nature.
[202] Jean Mosser,et al. Putative X-linked adrenoleukodystrophy gene shares unexpected homology with ABC transporters , 1993, Nature.
[203] S. Tonegawa,et al. TAP1 mutant mice are deficient in antigen presentation, surface class I molecules, and CD4−8+ T cells , 1992, Cell.
[204] A. Duncan,et al. Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line. , 1992, Science.
[205] C. Higgins,et al. ABC transporters: from microorganisms to man. , 1992, Annual review of cell biology.
[206] Wendy L. Kimber,et al. Cystic fibrosis in the mouse by targeted insertional mutagenesis , 1992, Nature.
[207] B. Koller,et al. An Animal Model for Cystic Fibrosis Made by Gene Targeting , 1992, Science.
[208] William R. Taylor,et al. The rapid generation of mutation data matrices from protein sequences , 1992, Comput. Appl. Biosci..
[209] H. Moser,et al. Mutations in the 70K peroxisomal membrane protein gene in Zellweger syndrome , 1992, Nature Genetics.
[210] M. White,et al. Congenital bilateral absence of the vas deferens. A primarily genital form of cystic fibrosis. , 1992 .
[211] L. Hagenfeldt,et al. Adrenomyeloneuropathy—report on a family , 1991, Journal of internal medicine.
[212] M. Griffin,et al. Isolation and characterization of Drosophila multidrug resistance gene homologs , 1991, Molecular and cellular biology.
[213] I. Roninson,et al. Expression and activity of P-glycoprotein, a multidrug efflux pump, in human hematopoietic stem cells , 1991, Cell.
[214] J. Monaco,et al. Transport protein genes in the murine MHC: possible implications for antigen processing. , 1990, Science.
[215] S. Beck,et al. Sequences encoded in the class II region of the MHC related to the 'ABC' superfamily of transporters , 1990, Nature.
[216] R. Demars,et al. A gene in the human major histocompatibility complex class II region controlling the class I antigen presentation pathway , 1990, Nature.
[217] Michael J. Hartshorn,et al. Structural model of ATP-binding proteing associated with cystic fibrosis, multidrug resistance and bacterial transport , 1990, Nature.
[218] M. Leppert,et al. Multiple mutations in highly conserved residues are found in mildly affected cystic fibrosis patients , 1990, Cell.
[219] J. Riordan,et al. Identification of the Cystic Fibrosis Gene : Chromosome Walking and Jumping Author ( s ) : , 2008 .
[220] L. Tsui,et al. Erratum: Identification of the Cystic Fibrosis Gene: Cloning and Characterization of Complementary DNA , 1989, Science.
[221] L. Tsui,et al. Erratum: Identification of the Cystic Fibrosis Gene: Genetic Analysis , 1989, Science.
[222] N. Saitou,et al. The neighbor-joining method: a new method for reconstructing phylogenetic trees. , 1987, Molecular biology and evolution.
[223] D. Mccormick. Sequence the Human Genome , 1986, Bio/Technology.
[224] I. Pastan,et al. Isolation of human mdr DNA sequences amplified in multidrug-resistant KB carcinoma cells. , 1986, Proceedings of the National Academy of Sciences of the United States of America.
[225] D. S. Lin,et al. Abnormal metabolism of shellfish sterols in a patient with sitosterolemia and xanthomatosis. , 1986, The Journal of clinical investigation.
[226] P. Cresswell,et al. Impaired assembly and transport of HLA‐A and ‐B antigens in a mutant TxB cell hybrid. , 1986, The EMBO journal.
[227] J. Riordan,et al. Amplification of P-glycoprotein genes in multidrug-resistant mammalian cell lines , 1985, Nature.
[228] H. Lipkin. Where is the ?c? , 1978 .
[229] R L Juliano,et al. A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants. , 1976, Biochimica et biophysica acta.
[230] W. Connor,et al. Beta-sitosterolemia and xanthomatosis. A newly described lipid storage disease in two sisters. , 1974, The Journal of clinical investigation.
[231] M. Gottesman,et al. Multidrug resistance in cancer: role of ATP–dependent transporters , 2002, Nature Reviews Cancer.
[232] Anand K. Srivastava,et al. Identification of a gene, ABCG5, important in the regulation of dietary cholesterol absorption , 2001, Nature Genetics.
[233] T. Fojo,et al. An ATP-binding cassette gene (ABCG3) closely related to the multidrug transporter ABCG2 (MXR/ABCP) has an unusual ATP-binding domain , 2001, Mammalian Genome.
[234] International Human Genome Sequencing Consortium. Initial sequencing and analysis of the human genome , 2001, Nature.
[235] L. Doyle,et al. Fumitremorgin C reverses multidrug resistance in cells transfected with the breast cancer resistance protein. , 2000, Cancer research.
[236] T. Litman,et al. Molecular cloning of cDNAs which are highly overexpressed in mitoxantrone-resistant cells: demonstration of homology to ABC transport genes. , 1999, Cancer research.
[237] P. Quinton. Physiological basis of cystic fibrosis: a historical perspective. , 1999, Physiological reviews.
[238] Robert D. Finn,et al. Pfam 3.1: 1313 multiple alignments and profile HMMs match the majority of proteins , 1999, Nucleic Acids Res..
[239] S. Almashanu,et al. CHAPTER 24 – PEROXISOMAL ABC TRANSPORTERS , 2003 .
[240] M. Gottesman,et al. ABC transporters : biochemical, cellular, and molecular aspects , 1998 .
[241] Sean R. Eddy,et al. Profile hidden Markov models , 1998, Bioinform..
[242] M. Dean,et al. Retinitis pigmentosa caused by a homozygous mutation in the Stargardt disease gene ABCR , 1998, Nature Genetics.
[243] X. Estivill,et al. Geographic distribution and regional origin of 272 cystic fibrosis mutations in European populations , 1997 .
[244] S. Michaelis,et al. Sequence comparison of yeast ATP-binding cassette proteins. , 1995, Cold Spring Harbor symposia on quantitative biology.
[245] Sean R. Eddy,et al. Multiple Alignment Using Hidden Markov Models , 1995, ISMB.
[246] V. Ling,et al. The MDR superfamily of genes and its biological implications. , 1994, Important advances in oncology.
[247] J. Mosser,et al. Adrenoleukodystrophy gene: unexpected homology to a protein involved in peroxisome biogenesis. , 1993, Biochimie.
[248] J. Riordan,et al. The cystic fibrosis transmembrane conductance regulator. , 1993, Annual review of physiology.
[249] David J Brayden,et al. Cystic fibrosis, the CFTR, and rectifying Cl- channels. , 1991, Advances in experimental medicine and biology.
[250] V. Ling,et al. Detection of P-glycoprotein in multidrug-resistant cell lines by monoclonal antibodies , 1985, Nature.
[251] L. Pauling,et al. Evolutionary Divergence and Convergence in Proteins , 1965 .