Alterations of Transcription of Genes Coding Anti-oxidative and Mitochondria-Related Proteins in Amyloid β Toxicity: Relevance to Alzheimer’s Disease
暂无分享,去创建一个
W. Lukiw | J. Strosznajder | R. Strosznajder | V. Jaber | P. Wencel | M. Cieślik | G. Czapski | S. Wójtowicz | Iga Wieczorek
[1] J. Morales-Garcia,et al. Novel Approaches for the Treatment of Alzheimer’s and Parkinson’s Disease , 2019, International journal of molecular sciences.
[2] P. Reddy,et al. Mitochondrial division inhibitor 1 reduces dynamin-related protein 1 and mitochondrial fission activity , 2018, Human molecular genetics.
[3] M. Monteiro,et al. Neuroprotective Mechanisms of Resveratrol in Alzheimer's Disease: Role of SIRT1 , 2018, Oxidative medicine and cellular longevity.
[4] C. Peng,et al. Overview of MicroRNA Biogenesis, Mechanisms of Actions, and Circulation , 2018, Front. Endocrinol..
[5] Winnie S. Liang,et al. Amyloid-β Increases Tau by Mediating Sirtuin 3 in Alzheimer’s Disease , 2018, Molecular Neurobiology.
[6] Ana Martínez,et al. Amyloid β-induced impairments on mitochondrial dynamics, hippocampal neurogenesis, and memory are restored by phosphodiesterase 7 inhibition , 2018, Alzheimer's Research & Therapy.
[7] J. Strosznajder,et al. Inhibition of poly(ADP-ribose) polymerase-1 alters expression of mitochondria-related genes in PC12 cells: relevance to mitochondrial homeostasis in neurodegenerative disorders. , 2018, Biochimica et biophysica acta. Molecular cell research.
[8] Yixin Li,et al. SIRT1/PGC-1α Signaling Promotes Mitochondrial Functional Recovery and Reduces Apoptosis after Intracerebral Hemorrhage in Rats , 2018, Front. Mol. Neurosci..
[9] W. Lukiw,et al. Up-regulated Pro-inflammatory MicroRNAs (miRNAs) in Alzheimer’s disease (AD) and Age-Related Macular Degeneration (AMD) , 2018, Cellular and Molecular Neurobiology.
[10] A. Adamczyk,et al. Inhibition of cyclin-dependent kinase 5 affects early neuroinflammatory signalling in murine model of amyloid beta toxicity , 2018, Journal of Neuroinflammation.
[11] R. Swerdlow. Mitochondria and Mitochondrial Cascades in Alzheimer’s Disease , 2017, Journal of Alzheimer's disease : JAD.
[12] P. Reddy,et al. Aqua-soluble DDQ reduces the levels of Drp1 and A&bgr; and inhibits abnormal interactions between A&bgr; and Drp1 and protects Alzheimer’s disease neurons from A&bgr;- and Drp1-induced mitochondrial and synaptic toxicities , 2017, Human molecular genetics.
[13] Maxim N. Artyomov,et al. TREM2 Maintains Microglial Metabolic Fitness in Alzheimer’s Disease , 2017, Cell.
[14] W. Lukiw,et al. Inhibition of Poly(ADP-ribose) Polymerase-1 Enhances Gene Expression of Selected Sirtuins and APP Cleaving Enzymes in Amyloid Beta Cytotoxicity , 2017, Molecular Neurobiology.
[15] A. Grimm,et al. Brain aging and neurodegeneration: from a mitochondrial point of view , 2017, Journal of neurochemistry.
[16] L. Saso,et al. Proteinopathy, oxidative stress and mitochondrial dysfunction: cross talk in Alzheimer’s disease and Parkinson’s disease , 2017, Drug design, development and therapy.
[17] Y. Zhao,et al. Alterations in micro RNA-messenger RNA (miRNA-mRNA) Coupled Signaling Networks in Sporadic Alzheimer’s Disease (AD) Hippocampal CA1 , 2017, Journal of Alzheimer's disease & Parkinsonism.
[18] K. Green,et al. Inflammation in Alzheimer’s disease: Lessons learned from microglia-depletion models , 2017, Brain, Behavior, and Immunity.
[19] L. Polito,et al. Sirtuin Modulation as Novel Neuroprotective Strategy for Alzheimer’s Disease , 2017 .
[20] Ramesh Kandimalla,et al. Protective effects of reduced dynamin-related protein 1 against amyloid beta-induced mitochondrial dysfunction and synaptic damage in Alzheimer's disease. , 2016, Human molecular genetics.
[21] J. Strosznajder,et al. Sirtuins and Their Roles in Brain Aging and Neurodegenerative Disorders , 2016, Neurochemical Research.
[22] De-Pei Liu,et al. SIRT1 deacetylates the cardiac transcription factor Nkx2.5 and inhibits its transcriptional activity , 2016, Scientific Reports.
[23] R. Strosznajder,et al. Sirtuins and their interactions with transcription factors and poly(ADP-ribose) polymerases. , 2016, Folia neuropathologica.
[24] Ramesh Kandimalla,et al. Multiple faces of dynamin-related protein 1 and its role in Alzheimer's disease pathogenesis. , 2016, Biochimica et biophysica acta.
[25] A. Najafi,et al. Eliminating microglia in Alzheimer's mice prevents neuronal loss without modulating amyloid-β pathology. , 2016, Brain : a journal of neurology.
[26] J. Hardy,et al. The amyloid hypothesis of Alzheimer's disease at 25 years , 2016, EMBO molecular medicine.
[27] H. Lassmann,et al. Oxidative stress and its impact on neurons and glia in multiple sclerosis lesions. , 2016, Biochimica et biophysica acta.
[28] T. Ekblad,et al. Sirtuins are Unaffected by PARP Inhibitors Containing Planar Nicotinamide Bioisosteres , 2016, Chemical biology & drug design.
[29] Joseph E. Parisi,et al. Altered brain energetics induces mitochondrial fission arrest in Alzheimer’s Disease , 2016, Scientific Reports.
[30] M. Meyer-Luehmann,et al. Forebrain microglia from wild-type but not adult 5xFAD mice prevent amyloid-β plaque formation in organotypic hippocampal slice cultures , 2015, Scientific Reports.
[31] J. Strosznajder,et al. The Molecular Mechanism of Amyloid β42 Peptide Toxicity: The Role of Sphingosine Kinase-1 and Mitochondrial Sirtuins , 2015, PloS one.
[32] Burkhard Becher,et al. Immune attack: the role of inflammation in Alzheimer disease , 2015, Nature Reviews Neuroscience.
[33] S. Mori,et al. Sirtuin 1 activator SRT2104 protects Huntington's disease mice , 2014, Annals of clinical and translational neurology.
[34] F. Metzger,et al. Amyloid-β peptide induces mitochondrial dysfunction by inhibition of preprotein maturation. , 2014, Cell metabolism.
[35] R. Swerdlow,et al. The Alzheimer's disease mitochondrial cascade hypothesis: progress and perspectives. , 2014, Biochimica et biophysica acta.
[36] Weiwei Dang. The controversial world of sirtuins. , 2014, Drug discovery today. Technologies.
[37] B. Palmier,et al. Neurological and Histological Consequences Induced by In Vivo Cerebral Oxidative Stress: Evidence for Beneficial Effects of SRT1720, a Sirtuin 1 Activator, and Sirtuin 1-Mediated Neuroprotective Effects of Poly(ADP-ribose) Polymerase Inhibition , 2014, PloS one.
[38] Walter J. Lukiw,et al. Circular RNA (circRNA) in Alzheimer's disease (AD) , 2013, Front. Genet..
[39] E. Bossy‐Wetzel,et al. Forever young: SIRT3 a shield against mitochondrial meltdown, aging, and neurodegeneration , 2013, Front. Aging Neurosci..
[40] L. Guarente,et al. The NAD+/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling , 2013, Cell.
[41] R. Patel,et al. Interaction of Sirt3 with OGG1 contributes to repair of mitochondrial DNA and protects from apoptotic cell death under oxidative stress , 2013, Cell Death and Disease.
[42] N. Inestrosa,et al. Peroxisome Proliferator-Activated Receptor (PPAR) γ and PPARα Agonists Modulate Mitochondrial Fusion-Fission Dynamics: Relevance to Reactive Oxygen Species (ROS)-Related Neurodegenerative Disorders? , 2013, PloS one.
[43] David A Bennett,et al. Brain amyloid-β oligomers in ageing and Alzheimer's disease. , 2013, Brain : a journal of neurology.
[44] A. M. van der Bliek,et al. Mitochondrial Fission, Fusion, and Stress , 2012, Science.
[45] V. Pertegato,et al. Assessment of mitochondrial respiratory chain enzymatic activities on tissues and cultured cells , 2012, Nature Protocols.
[46] J. Götz,et al. Insights into mitochondrial dysfunction: aging, amyloid-β, and tau-A deleterious trio. , 2012, Antioxidants & redox signaling.
[47] A. Adamczyk,et al. Poly(ADP-ribose) Polymerase-1 in Amyloid Beta Toxicity and Alzheimer's Disease , 2012, Molecular Neurobiology.
[48] P. Reddy,et al. Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage. , 2011, Human molecular genetics.
[49] L. Guarente,et al. The SirT3 divining rod points to oxidative stress. , 2011, Molecular cell.
[50] T. Wenz. Mitochondria and PGC-1α in Aging and Age-Associated Diseases , 2011, Journal of aging research.
[51] J. Auwerx,et al. PARP-1 inhibition increases mitochondrial metabolism through SIRT1 activation. , 2011, Cell metabolism.
[52] E. Galea,et al. Frontiers in Aging Neuroscience Aging Neuroscience Epidemiological Data and Clinical Trials , 2022 .
[53] Nicholas T. Ingolia,et al. Mammalian microRNAs predominantly act to decrease target mRNA levels , 2010, Nature.
[54] A. Eckert,et al. Mitochondrial Dysfunction: Common Final Pathway in Brain Aging and Alzheimer’s Disease—Therapeutic Aspects , 2010, Molecular Neurobiology.
[55] G. Landreth,et al. Microglia and inflammation in Alzheimer's disease. , 2010, CNS & neurological disorders drug targets.
[56] V. Perry,et al. Systemic inflammation and disease progression in Alzheimer disease , 2009, Neurology.
[57] George Perry,et al. Impaired Balance of Mitochondrial Fission and Fusion in Alzheimer's Disease , 2009, The Journal of Neuroscience.
[58] George Perry,et al. The role of abnormal mitochondrial dynamics in the pathogenesis of Alzheimer’s disease , 2009, Journal of neurochemistry.
[59] D. Bennett,et al. Sirtuin 1 Reduction Parallels the Accumulation of Tau in Alzheimer Disease , 2009, Journal of neuropathology and experimental neurology.
[60] G. Small,et al. Cognitive and cerebral metabolic effects of celecoxib versus placebo in people with age-related memory loss: randomized controlled study. , 2008, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.
[61] C. Deng,et al. SIRT3 interacts with the daf-16 homolog FOXO3a in the Mitochondria, as well as increases FOXO3a Dependent Gene expression , 2008, International journal of biological sciences.
[62] Á. Simonyi,et al. Amyloid beta peptide and NMDA induce ROS from NADPH oxidase and AA release from cytosolic phospholipase A2 in cortical neurons , 2008, Journal of neurochemistry.
[63] J. McCaffery,et al. Mitochondrial Fusion Protects against Neurodegeneration in the Cerebellum , 2007, Cell.
[64] C. Masters,et al. Copper‐dependent inhibition of cytochrome c oxidase by Aβ1−42 requires reduced methionine at residue 35 of the Aβ peptide , 2006 .
[65] J. Quinn,et al. Mitochondria are a direct site of A beta accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression. , 2006, Human molecular genetics.
[66] M. Gallagher,et al. A specific amyloid-β protein assembly in the brain impairs memory , 2006, Nature.
[67] Michela Gallagher,et al. A specific amyloid-beta protein assembly in the brain impairs memory. , 2006, Nature.
[68] C. Masters,et al. Copper-dependent inhibition of cytochrome c oxidase by Abeta(1-42) requires reduced methionine at residue 35 of the Abeta peptide. , 2006, Journal of neurochemistry.
[69] L. Mucke,et al. SIRT1 Protects against Microglia-dependent Amyloid-β Toxicity through Inhibiting NF-κB Signaling* , 2005, Journal of Biological Chemistry.
[70] Y. Lyubchenko,et al. Physicochemical characteristics of soluble oligomeric Aβ and their pathologic role in Alzheimer's disease , 2005, Neurological research.
[71] C. Masters,et al. Copper-Dependent Inhibition of Human Cytochrome c Oxidase by a Dimeric Conformer of Amyloid-β1-42 , 2005, The Journal of Neuroscience.
[72] L. Mucke,et al. SIRT1 protects against microglia-dependent amyloid-beta toxicity through inhibiting NF-kappaB signaling. , 2005, The Journal of biological chemistry.
[73] A. Hilliker,et al. RNA interference-mediated silencing of Sod2 in Drosophila leads to early adult-onset mortality and elevated endogenous oxidative stress , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[74] Mark A. Smith,et al. Alzheimer Disease and Oxidative Stress , 2002, Journal of Biomedicine and Biotechnology.
[75] A. Nunomura,et al. Oxidative Damage Is the Earliest Event in Alzheimer Disease , 2001, Journal of neuropathology and experimental neurology.
[76] M. Smith,et al. Oxidative stress in Alzheimer's disease. , 2000, Biochimica et biophysica acta.
[77] H. Möller,et al. A selective defect of cytochrome c oxidase is present in brain of Alzheimer disease patients , 2000, Neurobiology of Aging.
[78] Y. Christen,et al. Oxidative stress and Alzheimer disease. , 2000, The American journal of clinical nutrition.
[79] A. Nunomura,et al. Oxidative stress in Alzheimers disease , 2000 .
[80] M. Matzuk,et al. Neurodegeneration, myocardial injury, and perinatal death in mitochondrial superoxide dismutase-deficient mice. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[81] M. Beal,et al. Cortical Cytochrome Oxidase Activity Is Reduced in Alzheimer's Disease , 1994, Journal of neurochemistry.
[82] J. Hardy,et al. Amyloid deposition as the central event in the aetiology of Alzheimer's disease. , 1991, Trends in pharmacological sciences.