Pregnancy with leiomyoma uteri and feto-maternal outcomes

Objective: Evaluation of fetal and maternal outcomes in pregnancy with leiomyoma uteri. Methods: Total 50 pregnant women with uterine myoma attending the department of Obstetrics and Gynecology of IPGME&R, Kolkata were followed during the antenatal, intranatal and postnatal period. Total 200 women of normal uncomplicated pregnancy were recruited as control and matched for age and parity. Results: The women were having 10% submucous, 74% intramural and 16% subserous type of uterine myoma. Highest incidence was in more than 30 yrs age group. Spontaneous miscarriage in 16%, malpresentation in 14%, fetal growth restriction (FGR) in 14%, intra uterine fetal demise (IUFD) in 8% and placental abruption in 8% cases were noted. During intranatal period preterm labour in 18%, prolonged labour in 22%, fetal distress in 22%, retained placenta in 6% and preterm premature rupture of membranes (PPROM) or premature rupture of membranes (PROM) in 16% cases were also seen. Postpartum hemorrhage (PPH) in 22% and subinvolution in 14% cases were found. APGAR score was less than seven in 18% babies and 46% babies weighed low birth weight. Conclusion: Pregnancies complicated with uterine myoma adversely affect fetal and maternal outcomes.

[1]  C. Allaire,et al.  The management of uterine leiomyomas. , 2015, Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC.

[2]  Y. Tan,et al.  Rare postpartum ruptured degenerated fibroid: A case report , 2014, The journal of obstetrics and gynaecology research.

[3]  Q. Ain,et al.  PREGNANCY WITH FIBROIDS AND ITS OBSTETRIC COMPLICATIONS , 2009 .

[4]  Naushaba Rizwan,et al.  Retained placenta still a continuing cause of maternal morbidity and mortality. , 2009, JPMA. The Journal of the Pakistan Medical Association.

[5]  A. Caughey,et al.  Fibroids and reproductive outcomes: a systematic literature review from conception to delivery. , 2008, American journal of obstetrics and gynecology.

[6]  A. Caughey,et al.  Obstetric Outcomes in Women With Sonographically Identified Uterine Leiomyomata , 2006, Obstetrics and gynecology.

[7]  J. Palmer,et al.  Age-Specific Incidence Rates for Self-Reported Uterine Leiomyomata in the Black Women's Health Study , 2005, Obstetrics and gynecology.

[8]  E. Wallach,et al.  Uterine Myomas: An Overview of Development, Clinical Features, and Management , 2004, Obstetrics and gynecology.

[9]  P. Doubilet,et al.  Outcome of pregnancies in women with uterine leiomyomas identified by sonography in the first trimester , 2001, Journal of clinical ultrasound : JCU.

[10]  W. Droegemueller,et al.  Complications of Uterine Leiomyomas in Pregnancy , 1989, Obstetrics and gynecology.

[11]  D. Muram,et al.  Myomas of the uterus in pregnancy: ultrasonographic follow-up. , 1980, American journal of obstetrics and gynecology.

[12]  K. Jayakrishnan,et al.  Submucous fibroids and infertility: Effect of hysteroscopic myomectomy and factors influencing outcome , 2013, Journal of human reproductive sciences.

[13]  C. Birch,et al.  The management of uterine leiomyomas. , 2003, Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC.