Intrathymic Parathyroid Adenoma

Introduction: Mediastinal parathyroid adenoma localization is a rare entity. We report a case of excision by manubriotomy of intrathymic parathyroid adenoma detected by Computed Tomography scan of the chest and neck and confirmed by Technetium-99 m-sestamibi scan (99 mTc-MIBI). Case Presentation: A 68 years old woman with history of hypercalcaemia, PTH elevation and operation for pathological fracture of the left femur 7 days before was presented to our service. The patient underwent manubriotomy and the adenoma was found within the right lobe of the thymus gland. Conclusion: The Technetium-99 m-sestamibi scan evaluation can be useful in the preoperative localization of ectopic parathyroid adenomas. The surgical approach by manubriotomy is privileged when the ectopic adenoma is in the upper part of anterior mediastinum.

[1]  V. Pantelidou,et al.  Gamma probe-assisted excision of an ectopic parathyroid adenoma located within the thymus: case report and review of the literature , 2014, Journal of Cardiothoracic Surgery.

[2]  N. Kawoosa,et al.  Intrathymic parathyroid adenoma , 2012, Indian Journal of Thoracic and Cardiovascular Surgery.

[3]  M. Iacobone,et al.  The results of surgery for mediastinal parathyroid tumors: a comparative study of 63 patients , 2010, Langenbeck's Archives of Surgery.

[4]  A. Sitges-Serra,et al.  Surgical strategy for sporadic primary hyperparathyroidism an evidence-based approach to surgical strategy, patient selection, surgical access, and reoperations , 2009, Langenbeck's Archives of Surgery.

[5]  M. Ghesani,et al.  Gamma Probe Detection of Ectopic Parathyroid Adenoma , 2015, Radiology case reports.

[6]  D. Moka,et al.  Thoracoscopic Removal of Mediastinal Hyperfunctioning Parathyroid Glands: Personal Experience and Review of the Literature , 2008, World Journal of Surgery.

[7]  M. Marzola,et al.  Technetium-99m sestamibi scintigraphy and helical CT together in patients with primary hyperparathyroidism: a prospective clinical study. , 2004, The British journal of radiology.

[8]  R. Malthaner,et al.  Intraoperative radioguided thoracoscopic removal of ectopic parathyroid adenoma. , 2001, The Annals of thoracic surgery.

[9]  R. Henkin,et al.  Resection of parathyroid tumor in the aorticopulmonary window without prior neck exploration. , 1988, Surgery.

[10]  O. Clark Mediastinal parathyroid tumors. , 1988, Archives of surgery.