Isoforms of protein 4.1 are differentially distributed in heart muscle cells: relation of 4.1R and 4.1G to components of the Ca2+ homeostasis system.

[1]  Norbert Frey,et al.  Cardiac Z-disc Signaling Network* , 2011, The Journal of Biological Chemistry.

[2]  Thomas J Hund,et al.  A β(IV)-spectrin/CaMKII signaling complex is essential for membrane excitability in mice. , 2010, The Journal of clinical investigation.

[3]  Y. Takakuwa,et al.  Two different unique cardiac isoforms of protein 4.1R in zebrafish, Danio rerio, and insights into their cardiac functions as related to their unique structures , 2010, Development, growth & differentiation.

[4]  A. Baines The spectrin–ankyrin–4.1–adducin membrane skeleton: adapting eukaryotic cells to the demands of animal life , 2010, Protoplasma.

[5]  R. Bloch,et al.  Characterization and expression of a heart-selective alternatively spliced variant of alpha II-spectrin, cardi+, during development in the rat. , 2010, Journal of molecular and cellular cardiology.

[6]  G. Debnath,et al.  Protein 4.1R links E-cadherin/beta-catenin complex to the cytoskeleton through its direct interaction with beta-catenin and modulates adherens junction integrity. , 2009, Biochimica et biophysica acta.

[7]  A. Baines,et al.  Protein 4.1 and the control of ion channels. , 2009, Blood cells, molecules & diseases.

[8]  E. Olson,et al.  Heterotrimeric G proteins regulate a noncanonical function of septate junction proteins to maintain cardiac integrity in Drosophila. , 2008, Developmental cell.

[9]  M. Yacoub,et al.  Cytoskeletal Protein 4.1r Affects Repolarization and Regulates Calcium Handling in the Cytoskeletal Protein 4.1r Affects Repolarization and Regulates Calcium Handling in the Heart Materials and Methods 4.1r-deficient Mice Cellular Studies Statistical Analysis Stagg Et Al Deficiency of Protein 4.1r a , 2022 .

[10]  D. Rossi,et al.  The Sarcoplasmic Reticulum: An Organized Patchwork of Specialized Domains , 2008, Traffic.

[11]  Yang Yang,et al.  Protein 4.1R-dependent multiprotein complex: New insights into the structural organization of the red blood cell membrane , 2008, Proceedings of the National Academy of Sciences.

[12]  O. Palygin,et al.  Voltage-gated Nav channel targeting in the heart requires an ankyrin-G–dependent cellular pathway , 2008, The Journal of cell biology.

[13]  W. Schilling,et al.  TRPC3 channels colocalize with Na+/Ca2+ exchanger and Na+ pump in axial component of transverse-axial tubular system of rat ventricle. , 2007, American journal of physiology. Heart and circulatory physiology.

[14]  G. Debnath,et al.  Phosphatidylinositol-4,5-biphosphate (PIP2) differentially regulates the interaction of human erythrocyte protein 4.1 (4.1R) with membrane proteins. , 2006, Biochemistry.

[15]  A. Baines,et al.  The transitional junction: a new functional subcellular domain at the intercalated disc. , 2006, Molecular biology of the cell.

[16]  Vann Bennett,et al.  Ankyrin-B Coordinates the Na/K ATPase, Na/Ca Exchanger, and InsP3 Receptor in a Cardiac T-Tubule/SR Microdomain , 2005, PLoS biology.

[17]  M. Nathanson,et al.  Protein 4.1N does not interact with the inositol 1,4,5-trisphosphate receptor in an epithelial cell line. , 2005, Cell calcium.

[18]  A. Baines,et al.  The spectrin-associated cytoskeleton in mammalian heart. , 2005, Frontiers in bioscience : a journal and virtual library.

[19]  G. Debnath,et al.  Identification and Functional Characterization of Protein 4.1R and Actin-Binding Sites in Erythrocyte β Spectrin: Regulation of the Interactions by Phosphatidylinositol-4,5-bisphosphate† , 2005 .

[20]  M. Yacoub,et al.  Cardiac muscle cell cytoskeletal protein 4.1: Analysis of transcripts and subcellular location—relevance to membrane integrity, microstructure, and possible role in heart failure , 2005, Mammalian Genome.

[21]  N. Mohandas,et al.  Phospholipid binding by proteins of the spectrin family: a comparative study. , 2005, Biochemical and biophysical research communications.

[22]  Carlo Napolitano,et al.  Nav1.5 E1053K mutation causing Brugada syndrome blocks binding to ankyrin-G and expression of Nav1.5 on the surface of cardiomyocytes. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[23]  K. Mikoshiba,et al.  Lateral Diffusion of Inositol 1,4,5-Trisphosphate Receptor Type 1 Is Regulated by Actin Filaments and 4.1N in Neuronal Dendrites* , 2004, Journal of Biological Chemistry.

[24]  J. Conboy,et al.  Differential domain evolution and complex RNA processing in a family of paralogous EPB41 (protein 4.1) genes facilitate expression of diverse tissue-specific isoforms. , 2004, Genomics.

[25]  E. F. Stanley,et al.  A Syntaxin 1, Gαo, and N-Type Calcium Channel Complex at a Presynaptic Nerve Terminal: Analysis by Quantitative Immunocolocalization , 2004, The Journal of Neuroscience.

[26]  P. Gallagher,et al.  Hereditary elliptocytosis: spectrin and protein 4.1R. , 2004, Seminars in hematology.

[27]  N. Mohandas,et al.  Phosphatidylserine binding sites in erythroid spectrin: location and implications for membrane stability. , 2004, Biochemistry.

[28]  Ole Petter Ottersen,et al.  Localization and function of the Na+/Ca2+-exchanger in normal and detubulated rat cardiomyocytes. , 2003, Journal of molecular and cellular cardiology.

[29]  J. Conboy,et al.  Distinct distribution of specific members of protein 4.1 gene family in the mouse nephron. , 2003, Kidney international.

[30]  A. Gramolini,et al.  Ankyrin-B mutation causes type 4 long-QT cardiac arrhythmia and sudden cardiac death , 2003, Nature.

[31]  I. Bezprozvanny,et al.  Association of the type 1 inositol (1,4,5)-trisphosphate receptor with 4.1N protein in neurons , 2003, Molecular and Cellular Neuroscience.

[32]  K. Keinänen,et al.  Surface Expression of GluR-D AMPA Receptor Is Dependent on an Interaction between Its C-Terminal Domain and a 4.1 Protein , 2003, The Journal of Neuroscience.

[33]  R. Levenson,et al.  D2 and D3 dopamine receptor cell surface localization mediated by interaction with protein 4.1N. , 2002, Molecular pharmacology.

[34]  J. A. Gimm,et al.  Functional characterization of spectrin-actin-binding domains in 4.1 family of proteins. , 2002, Biochemistry.

[35]  J. Camonis,et al.  Tyrosine Phosphorylation Regulates Alpha II Spectrin Cleavage by Calpain , 2002, Molecular and Cellular Biology.

[36]  N. Mohandas,et al.  Identification of a functional role for lipid asymmetry in biological membranes: Phosphatidylserine-skeletal protein interactions modulate membrane stability , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[37]  J. Zhang,et al.  Ultrastructural and biochemical localization of N-RAP at the interface between myofibrils and intercalated disks in the mouse heart. , 2001, Biochemistry.

[38]  A. Baines,et al.  Properties of the C-terminal domain of 4.1 proteins. , 2001, European journal of biochemistry.

[39]  A. Baines,et al.  Spectrin and ankyrin-based pathways: metazoan inventions for integrating cells into tissues. , 2001, Physiological reviews.

[40]  M. Shattock,et al.  Differential centrifugation separates cardiac sarcolemmal and endosomal membranes from Langendorff-perfused rat hearts. , 2001, Analytical biochemistry.

[41]  A. Baines,et al.  Protein 4.1 in forebrain postsynaptic density preparations: enrichment of 4.1 gene products and detection of 4.1R binding proteins. , 2001, European journal of biochemistry.

[42]  P. Dan,et al.  Distribution of proteins implicated in excitation-contraction coupling in rat ventricular myocytes. , 2000, Biophysical journal.

[43]  W. Koch,et al.  The effect of Gi‐protein inactivation on basal, and β1‐ and β2AR‐stimulated contraction of myocytes from transgenic mice overexpressing the β2‐adrenoceptor , 2000 .

[44]  B. Han,et al.  Protein 4.1R core domain structure and insights into regulation of cytoskeletal organization , 2000, Nature Structural Biology.

[45]  I. Correas,et al.  A constitutive region is responsible for nuclear targeting of 4.1R: modulation by alternative sequences results in differential intracellular localization. , 2000, Journal of cell science.

[46]  E. Heerkens,et al.  Identification of a novel C-terminal variant of beta II spectrin: two isoforms of beta II spectrin have distinct intracellular locations and activities. , 2000, Journal of cell science.

[47]  J. A. Gimm,et al.  Molecular and Functional Characterization of Protein 4.1B, a Novel Member of the Protein 4.1 Family with High Level, Focal Expression in Brain* , 2000, The Journal of Biological Chemistry.

[48]  G. Lanfranchi,et al.  ZASP: a new Z-band alternatively spliced PDZ-motif protein. , 1999, The Journal of cell biology.

[49]  O. Ohara,et al.  Molecular characterization of a new member of the protein 4.1 family (brain 4.1) in rat brain. , 1999, Brain research. Molecular brain research.

[50]  J. Conboy,et al.  Protein 4.1R-deficient mice are viable but have erythroid membrane skeleton abnormalities. , 1999, The Journal of clinical investigation.

[51]  J. Conboy The Role of Alternative Pre-mRNA Splicing in Regulating the Structure and Function of Skeletal Protein 4.1 , 1999, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

[52]  J. Conboy,et al.  Characterization of multiple isoforms of protein 4.1R expressed during erythroid terminal differentiation. , 1998, Blood.

[53]  R. Fehon,et al.  Drosophila coracle, a member of the protein 4.1 superfamily, has essential structural functions in the septate junctions and developmental functions in embryonic and adult epithelial cells. , 1998, Molecular biology of the cell.

[54]  S. Snyder,et al.  Cloning and characterization of 4.1G (EPB41L2), a new member of the skeletal protein 4.1 (EPB41) gene family. , 1998, Genomics.

[55]  J. Conboy,et al.  Mechanochemistry of protein 4.1's spectrin-actin-binding domain: ternary complex interactions, membrane binding, network integration, structural strengthening , 1995, The Journal of cell biology.

[56]  S. Artavanis-Tsakonas,et al.  A Drosophila homologue of membrane-skeleton protein 4.1 is associated with septate junctions and is encoded by the coracle gene. , 1994, Development.

[57]  J. Conboy,et al.  Mechanochemistry of the alternatively spliced spectrin-actin binding domain in membrane skeletal protein 4.1. , 1993, The Journal of biological chemistry.

[58]  J. Aten,et al.  Measurement of co‐localization of objects in dual‐colour confocal images , 1993, Journal of microscopy.

[59]  D. Speicher,et al.  Identification of the functional site of erythrocyte protein 4.1 involved in spectrin-actin associations. , 1986, The Journal of biological chemistry.

[60]  V. Lehto,et al.  Intermediate filament and associated proteins in the human heart: an immunofluorescence study of normal and pathological hearts. , 1984, European heart journal.

[61]  U. K. Laemmli,et al.  Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4 , 1970, Nature.

[62]  N. Mohandas,et al.  Marked difference in membrane-protein-binding properties of the two isoforms of protein 4.1R expressed at early and late stages of erythroid differentiation. , 2009, The Biochemical journal.

[63]  M. Yacoub,et al.  Expression of human membrane skeleton protein genes for protein 4.1 and betaIISigma2-spectrin assayed by real-time RT-PCR. , 2005, Cellular & molecular biology letters.

[64]  A. Baines,et al.  Not Just a Plasma Membrane Protein: in Cardiac Muscle Cells Alpha-II Spectrin also Shows a Close Association with Myofibrils , 2004, Journal of Muscle Research & Cell Motility.

[65]  N. Sperelakis,et al.  Intercalated discs of mammalian heart: a review of structure and function. , 1985, Tissue & cell.

[66]  S. Craig,et al.  Gamma actin, spectrin, and intermediate filament proteins colocalize with vinculin at costameres, myofibril-to-sarcolemma attachment sites. , 1983, Cell motility.