Membrane ERα attenuates myocardial fibrosis via RhoA/ROCK-mediated actin remodeling in ovariectomized female infarcted rats

[1]  N. Turner,et al.  The role of cardiac fibroblasts in the transition from inflammation to fibrosis following myocardial infarction. , 2013, Vascular pharmacology.

[2]  Gao-lin Liu,et al.  Inhibition of Rho-kinase ameliorates myocardial remodeling and fibrosis in pressure overload and myocardial infarction: role of TGF-β1-TAK1. , 2012, Toxicology letters.

[3]  J. Gustafsson,et al.  Estrogen receptor β represses Akt signaling in breast cancer cells via downregulation of HER2/HER3 and upregulation of PTEN: implications for tamoxifen sensitivity , 2011, Breast Cancer Research.

[4]  P. Micevych,et al.  Estradiol Rapidly Regulates Membrane Estrogen Receptor α Levels in Hypothalamic Neurons , 2010, The Journal of Neuroscience.

[5]  E. Goldsmith,et al.  Temporal alterations in cardiac fibroblast function following induction of pressure overload , 2010, Cell and Tissue Research.

[6]  Felix Chua,et al.  Passive Stiffness of Myocardium From Congenital Heart Disease and Implications for Diastole , 2010, Circulation.

[7]  V. Regitz-Zagrosek,et al.  Regression of Myocardial Hypertrophy After Aortic Valve Replacement: Faster in Women? , 2009, Circulation.

[8]  V. Regitz-Zagrosek,et al.  17β-Estradiol inhibits matrix metalloproteinase-2 transcription via MAP kinase in fibroblasts , 2009, Cardiovascular research.

[9]  G. Lynch,et al.  Cytoskeletal Changes Underlie Estrogen's Acute Effects on Synaptic Transmission and Plasticity , 2009, The Journal of Neuroscience.

[10]  J. Downey,et al.  Oestrogen plays a permissive role in cardioprotection. , 2008, Cardiovascular research.

[11]  C. Simmons,et al.  Cofilin is a marker of myofibroblast differentiation in cells from porcine aortic cardiac valves. , 2008, American journal of physiology. Heart and circulatory physiology.

[12]  N. Chang,et al.  Physiological concentration of 17beta-estradiol on sympathetic reinnervation in ovariectomized infarcted rats. , 2008, Endocrinology.

[13]  E. Stefani,et al.  Heart estrogen receptor alpha: distinct membrane and nuclear distribution patterns and regulation by estrogen. , 2006, Journal of molecular and cellular cardiology.

[14]  T. Imaizumi,et al.  Pressure Overload–Induced Transient Oxidative Stress Mediates Perivascular Inflammation and Cardiac Fibrosis through Angiotensin II , 2006, Hypertension Research.

[15]  J. Hartwig,et al.  Cell surface actin remodeling , 2006, Journal of Cell Science.

[16]  T. Simoncini,et al.  Estrogen Receptor α Interacts with Gα13 to Drive Actin Remodeling and Endothelial Cell Migration via the RhoA/Rho Kinase/Moesin Pathway , 2006 .

[17]  Michael D. Schneider,et al.  Targeted deletion of ROCK1 protects the heart against pressure overload by inhibiting reactive fibrosis , 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[18]  Mark A Sussman,et al.  The Rac and Rho Hall of Fame: A Decade of Hypertrophic Signaling Hits , 2006, Circulation research.

[19]  Maria Sjöberg,et al.  Mechanisms of estrogen receptor signaling: convergence of genomic and nongenomic actions on target genes. , 2005, Molecular endocrinology.

[20]  A. Maggi,et al.  17β-Estradiol Inhibits Inflammatory Gene Expression by Controlling NF-κB Intracellular Localization , 2005, Molecular and Cellular Biology.

[21]  Eric R. Prossnitz,et al.  A Transmembrane Intracellular Estrogen Receptor Mediates Rapid Cell Signaling , 2005, Science.

[22]  Z. Ying,et al.  Activation of Rho/Rho kinase signaling pathway by reactive oxygen species in rat aorta. , 2004, American journal of physiology. Heart and circulatory physiology.

[23]  K. Wennerberg,et al.  Serine Phosphorylation Negatively Regulates RhoA in Vivo* , 2003, Journal of Biological Chemistry.

[24]  S. Davidge,et al.  Estrogen modulation of left ventricular remodeling in the aged heart. , 2003, Cardiovascular research.

[25]  D. Gingras,et al.  Phosphorylation states of Cdc42 and RhoA regulate their interactions with Rho GDP dissociation inhibitor and their extraction from biological membranes. , 2002, The Biochemical journal.

[26]  Y. T. Lee,et al.  Cardioprotective effects of 17 beta-estradiol produced by activation ofmitochondrial ATP-sensitive K(+)Channels in canine hearts. , 2000, Journal of molecular and cellular cardiology.

[27]  S. Narumiya,et al.  Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase. , 1999, Science.

[28]  R. Karas,et al.  Modulation of hypertensive heart disease by estrogen , 1996, Steroids.

[29]  C. Nobes,et al.  Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia , 1995, Cell.

[30]  J. Rouleau,et al.  Markedly different effects on ventricular remodeling result in a decrease in inducibility of ventricular arrhythmias. , 1994, Journal of the American College of Cardiology.

[31]  K. Weber,et al.  Cardiac interstitium in health and disease: the fibrillar collagen network. , 1989, Journal of the American College of Cardiology.

[32]  H. Stegemann,et al.  Determination of hydroxyproline. , 1967, Clinica chimica acta; international journal of clinical chemistry.

[33]  T. Simoncini,et al.  Estrogen receptor alpha interacts with Galpha13 to drive actin remodeling and endothelial cell migration via the RhoA/Rho kinase/moesin pathway. , 2006, Molecular endocrinology.

[34]  A. Maggi,et al.  17beta-estradiol inhibits inflammatory gene expression by controlling NF-kappaB intracellular localization. , 2005, Molecular and cellular biology.

[35]  T. Pollard,et al.  Cellular Motility Driven by Assembly and Disassembly of Actin Filaments , 2003, Cell.

[36]  木村 光宏 The Obesity in Bilateral Ovariectomized Rats is Related to a Decrease in the Expression of Leptin Receptors in the Brain , 2001 .