Early radiotherapy after radical prostatectomy improves cancer‐specific survival only in patients with highly aggressive prostate cancer: Validation of recently released criteria

To test the effect of radiotherapy administered within 6 months after radical prostatectomy on cancer‐specific mortality in prostate cancer patients after stratification according to a risk score.

[1]  F. Burkhard,et al.  Good outcome for patients with few lymph node metastases after radical retropubic prostatectomy. , 2008, European urology.

[2]  U. Capitanio,et al.  Impact of adjuvant radiation therapy on urinary continence recovery after radical prostatectomy. , 2014, European urology.

[3]  F. Montorsi,et al.  Survival benefit of radical prostatectomy in patients with localized prostate cancer: estimations of the number needed to treat according to tumor and patient characteristics. , 2012, The Journal of urology.

[4]  L. Hendrix,et al.  Trends in the use of postprostatectomy therapies for patients with prostate cancer: A Surveillance, Epidemiology, and End Results Medicare analysis , 2013, Cancer.

[5]  A. Garden,et al.  Reduced feeding tube duration with intensity‐modulated radiation therapy for head and neck cancer: A Surveillance, Epidemiology, and End Results‐Medicare Analysis , 2017, Cancer.

[6]  R. Gray.  A Class of $K$-Sample Tests for Comparing the Cumulative Incidence of a Competing Risk , 1988 .

[7]  S. Goldenberg,et al.  Adjuvant and salvage radiotherapy after prostatectomy: AUA/ASTRO Guideline. , 2013, The Journal of urology.

[8]  A multi-institutional matched-control analysis of adjuvant and salvage postoperative radiation therapy for pT3-4N0 prostate cancer. , 2008, Urology.

[9]  R. Valicenti,et al.  The efficacy of early adjuvant radiation therapy for pT3N0 prostate cancer: a matched-pair analysis. , 1999, International journal of radiation oncology, biology, physics.

[10]  A. Haese*,et al.  Biochemical recurrence after radical prostatectomy: multiplicative interaction between surgical margin status and pathological stage. , 2010, The Journal of urology.

[11]  C. Perneel,et al.  A multi-institutional analysis comparing adjuvant and salvage radiation therapy for high-risk prostate cancer patients with undetectable PSA after prostatectomy. , 2010, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[12]  L. Holmberg,et al.  Fifteen-year survival in prostate cancer. A prospective, population-based study in Sweden. , 1997, JAMA.

[13]  S. Lipsitz,et al.  Patterns of care and outcomes of radiotherapy for lymph node positivity after radical prostatectomy , 2013, BJU international.

[14]  E. Messing,et al.  Adjuvant radiotherapy for pathological T3N0M0 prostate cancer significantly reduces risk of metastases and improves survival: long-term followup of a randomized clinical trial. , 2009, The Journal of urology.

[15]  E. B. Butler,et al.  Salvage radiotherapy for recurrent prostate cancer after radical prostatectomy. , 2004, JAMA.

[16]  U. Capitanio,et al.  Selecting the optimal candidate for adjuvant radiotherapy after radical prostatectomy for prostate cancer: a long-term survival analysis. , 2013, European urology.

[17]  L. Collette,et al.  Postoperative radiotherapy after radical prostatectomy for high-risk prostate cancer: long-term results of a randomised controlled trial (EORTC trial 22911) , 2012, The Lancet.

[18]  F. Montorsi,et al.  Early salvage radiation therapy does not compromise cancer control in patients with pT3N0 prostate cancer after radical prostatectomy: results of a match-controlled multi-institutional analysis. , 2012, European urology.

[19]  Robert Gray,et al.  A Proportional Hazards Model for the Subdistribution of a Competing Risk , 1999 .

[20]  J L Warren,et al.  Development of a comorbidity index using physician claims data. , 2000, Journal of clinical epidemiology.

[21]  Richard K Valicenti,et al.  Predicting the outcome of salvage radiation therapy for recurrent prostate cancer after radical prostatectomy. , 2007, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[22]  Misop Han,et al.  Predicting 15-year prostate cancer specific mortality after radical prostatectomy. , 2011, The Journal of urology.

[23]  N. Willich,et al.  Phase III postoperative adjuvant radiotherapy after radical prostatectomy compared with radical prostatectomy alone in pT3 prostate cancer with postoperative undetectable prostate-specific antigen: ARO 96-02/AUO AP 09/95. , 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[24]  Combination of adjuvant hormonal and radiation therapy significantly prolongs survival of patients with pT2-4 pn+ prostate cancer: Results of a matched analysis , 2011 .

[25]  M. Kattan,et al.  Location, extent and number of positive surgical margins do not improve accuracy of predicting prostate cancer recurrence after radical prostatectomy. , 2009, The Journal of urology.

[26]  F. Fazio,et al.  Long-term follow-up of patients with prostate cancer and nodal metastases treated by pelvic lymphadenectomy and radical prostatectomy: the positive impact of adjuvant radiotherapy. , 2009, European urology.

[27]  L. Lacombe,et al.  The impact of solitary and multiple positive surgical margins on hard clinical end points in 1712 adjuvant treatment-naive pT2-4 N0 radical prostatectomy patients. , 2013, European urology.

[28]  Deborah Schrag,et al.  Overview of the SEER-Medicare Data: Content, Research Applications, and Generalizability to the United States Elderly Population , 2002, Medical care.