Sugar Content of Popular Sweetened Beverages Based on Objective Laboratory Analysis: Focus on Fructose Content

The consumption of fructose, largely in the form of high fructose corn syrup (HFCS), has risen over the past several decades and is thought to contribute negatively to metabolic health. However, the fructose content of foods and beverages produced with HFCS is not disclosed and estimates of fructose content are based on the common assumption that the HFCS used contains 55% fructose. The objective of this study was to conduct an objective laboratory analysis of the sugar content and composition in popular sugar‐sweetened beverages with a particular focus on fructose content. Twenty‐three sugar‐sweetened beverages along with four standard solutions were analyzed for sugar profiles using high‐performance liquid chromatography (HPLC) in an independent, certified laboratory. Total sugar content was calculated as well as percent fructose in the beverages that use HFCS as the sole source of fructose. Results showed that the total sugar content of the beverages ranged from 85 to 128% of what was listed on the food label. The mean fructose content in the HFCS used was 59% (range 47–65%) and several major brands appear to be produced with HFCS that is 65% fructose. Finally, the sugar profile analyses detected forms of sugar that were inconsistent with what was listed on the food labels. This analysis revealed significant deviations in sugar amount and composition relative to disclosures from producers. In addition, the tendency for use of HFCS that is higher in fructose could be contributing to higher fructose consumption than would otherwise be assumed.

[1]  Steven L Gortmaker,et al.  Relation between consumption of sugar-sweetened drinks and childhood obesity: a prospective, observational analysis , 2001, The Lancet.

[2]  W. Horwitz Official Methods of Analysis , 1980 .

[3]  P. Havel,et al.  Endocrine and metabolic effects of consuming beverages sweetened with fructose, glucose, sucrose, or high-fructose corn syrup. , 2008, The American journal of clinical nutrition.

[4]  K. Helrich,et al.  Official methods of Analysis of the AOAC. Volume 2. , 1990 .

[5]  Takahiko Nakagawa,et al.  Potential role of sugar (fructose) in the epidemic of hypertension, obesity and the metabolic syndrome, diabetes, kidney disease, and cardiovascular disease. , 2007, The American journal of clinical nutrition.

[6]  E. Parks,et al.  Dietary sugars stimulate fatty acid synthesis in adults. , 2008, The Journal of nutrition.

[7]  B. Popkin,et al.  Shifts in Patterns and Consumption of Beverages Between 1965 and 2002 , 2007, Obesity.

[8]  J. Manson,et al.  Sugar-sweetened beverages, weight gain, and incidence of type 2 diabetes in young and middle-aged women , 2004 .

[9]  J. Manson,et al.  Sweetened beverage consumption and risk of coronary heart disease in women. , 2009, The American journal of clinical nutrition.

[10]  J. White,et al.  Manufacturing, composition, and applications of fructose. , 1993, The American journal of clinical nutrition.

[11]  G. Bray How bad is fructose? , 2007, The American journal of clinical nutrition.

[12]  G. Curhan,et al.  Fructose consumption and the risk of kidney stones. , 2008, Kidney international.

[13]  F. Hu,et al.  Intake of sugar-sweetened beverages and weight gain: a systematic review. , 2006, The American journal of clinical nutrition.

[14]  Jaimie N. Davis,et al.  The relation of sugar intake to β cell function in overweight Latino children , 2005 .

[15]  W. Nseir,et al.  Soft drink consumption linked with fatty liver in the absence of traditional risk factors. , 2008, Canadian journal of gastroenterology = Journal canadien de gastroenterologie.

[16]  K. Brownell,et al.  Effects of soft drink consumption on nutrition and health: a systematic review and meta-analysis. , 2007, American journal of public health.

[17]  R. Townsend,et al.  Endocrine and metabolic effects of consuming fructose- and glucose-sweetened beverages with meals in obese men and women: influence of insulin resistance on plasma triglyceride responses. , 2009, The Journal of clinical endocrinology and metabolism.

[18]  B. Popkin,et al.  High-fructose corn syrup: is this what's for dinner? , 2008, The American journal of clinical nutrition.

[19]  A. Gaby Adverse effects of dietary fructose. , 2005, Alternative medicine review : a journal of clinical therapeutic.

[20]  Takahiko Nakagawa,et al.  A causal role for uric acid in fructose-induced metabolic syndrome. , 2006, American journal of physiology. Renal physiology.

[21]  Wei Zhang,et al.  Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humans. , 2009, The Journal of clinical investigation.

[22]  J. Montani,et al.  Fructose ingestion acutely elevates blood pressure in healthy young humans. , 2008, American journal of physiology. Regulatory, integrative and comparative physiology.

[23]  C. Verkoelen,et al.  Fructose intake as a risk factor for kidney stone disease. , 2008, Kidney international.

[24]  G. Bray,et al.  Consumption of high-fructose corn syrup in beverages may play a role in the epidemic of obesity. , 2004, The American journal of clinical nutrition.

[25]  S. Babey,et al.  Bubbling over: soda consumption and its link to obesity in California. , 2009, Policy brief.

[26]  R. Ferraris,et al.  Regulation of the fructose transporter GLUT5 in health and disease. , 2008, American journal of physiology. Endocrinology and metabolism.

[27]  G. Dallal,et al.  The accuracy of stated energy contents of reduced-energy, commercially prepared foods. , 2010, Journal of the American Dietetic Association.

[28]  Bernadette P Marriott,et al.  National estimates of dietary fructose intake increased from 1977 to 2004 in the United States. , 2009, The Journal of nutrition.

[29]  Jaimie N. Davis,et al.  The relation of sugar intake to beta cell function in overweight Latino children. , 2005, The American journal of clinical nutrition.

[30]  Frank B Hu,et al.  Sugar-sweetened beverages and incidence of type 2 diabetes mellitus in African American women. , 2008, Archives of internal medicine.

[31]  L. Tappy,et al.  Metabolic effects of fructose and the worldwide increase in obesity. , 2010, Physiological reviews.

[32]  John S. White,et al.  Straight talk about high-fructose corn syrup: what it is and what it ain't. , 2008, The American journal of clinical nutrition.