Molecular mechanisms underlying the anti‐proliferative and anti‐migratory effects of folate on homocysteine‐challenged rat aortic smooth muscle cells

Homocysteine is an intermediate product formed during the metabolism of methionine, and is increased in cells with folate deficiency. Patients with hyperhomocysteinemia tend to develop cardiovascular disease. Here, we have examined the molecular mechanisms underlying the anti‐proliferative and anti‐migratory effects of folate on homocysteine‐challenged rat aortic smooth muscle cells (RASMCs).

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