Effects of Surface Charges on Dental Implants: Past, Present, and Future

Osseointegration is a major factor influencing the success of dental implantation. To achieve rapid and strong, durable osseointegration, biomaterial researchers have investigated various surface treatment methods for dental subgingival titanium (Ti) implants. This paper focuses on surface-charge modification on the surface of titanium dental implants, which is a relatively new and very promising methodology for improving the implants' osseointegration properties. We give an overview on both theoretical explanations on how surface-charge affects the implants' osseointegration, as well as a potential surface charge modification method using sandblasting. Additionally, we discuss insights on the important factors affecting effectiveness of surface-charge modification methods and point out several interesting directions for future investigations on this topic.

[1]  H. M. Kim,et al.  Preparation of bioactive Ti and its alloys via simple chemical surface treatment. , 1996, Journal of biomedical materials research.

[2]  T. Albrektsson,et al.  Histologic investigations on 33 retrieved Nobelpharma implants. , 1993, Clinical materials.

[3]  D. Puleo,et al.  Understanding and controlling the bone-implant interface. , 1999, Biomaterials.

[4]  Yunzhi Yang,et al.  The effect of titanium surface roughening on protein absorption, cell attachment, and cell spreading. , 2008, The International journal of oral & maxillofacial implants.

[5]  R. Miron,et al.  Osteoinduction , 2012 .

[6]  C. Y. Guo,et al.  Insights into surface treatment methods of titanium dental implants , 2012 .

[7]  S. Fujibayashi,et al.  Positively charged bioactive Ti metal prepared by simple chemical and heat treatments , 2010, Journal of The Royal Society Interface.

[8]  Roger Watson,et al.  Tissue-integrated prostheses , 1985 .

[9]  J. Matinlinna,et al.  Silane based concepts on bonding resin composite to metals. , 2007, The journal of contemporary dental practice.

[10]  T. Kokubo,et al.  Bioactive glass ceramics: properties and applications. , 1991, Biomaterials.

[11]  R. Clark The chemistry of titanium and vanadium : an introduction to the chemistry of the early transition elements , 1968 .

[12]  Larry L. Hench,et al.  Bioceramics: From Concept to Clinic , 1991 .

[13]  J. Kendall Inorganic Chemistry , 1944, Nature.

[14]  B D Boyan,et al.  Role of material surfaces in regulating bone and cartilage cell response. , 1996, Biomaterials.

[15]  Panjian Li,et al.  The electrochemistry of a glass surface and its application to bioactive glass in solution , 1990 .

[16]  W. Marsden I and J , 2012 .

[17]  Takashi Nakamura,et al.  Effect of HCl concentrations on apatite-forming ability of NaOH–HCl- and heat-treated titanium metal , 2009, Journal of materials science. Materials in medicine.

[18]  T. Albrektsson,et al.  Osteoinduction, osteoconduction and osseointegration , 2001, European Spine Journal.

[19]  J. Andrade Surface and Interfacial Aspects of Biomedical Polymers , 1985 .

[20]  M. Barbosa,et al.  Attachment, spreading and short-term proliferation of human osteoblastic cells cultured on chitosan films with different degrees of acetylation , 2007, Journal of biomaterials science. Polymer edition.

[21]  K. Hing Bone repair in the twenty–first century: biology, chemistry or engineering? , 2004, Philosophical Transactions of the Royal Society of London. Series A: Mathematical, Physical and Engineering Sciences.

[22]  T. Miyazaki,et al.  Proliferation and differentiation of bone marrow cells on titanium plates treated with a wire-type electrical discharge machine. , 2000, The Journal of oral implantology.

[23]  P Ducheyne,et al.  Bioactive ceramic prosthetic coatings. , 1992, Clinical orthopaedics and related research.

[24]  John L. Brash,et al.  Proteins at Interfaces: Current Issues and Future Prospects , 1987 .

[25]  J. Matinlinna,et al.  A Novel Effect of Sandblasting on Titanium Surface –Static Charges Generation , 2013 .

[26]  C. Bell,et al.  Modern approach to inorganic chemistry , 1972 .

[27]  K. Yamashita,et al.  Manipulation of selective cell adhesion and growth by surface charges of electrically polarized hydroxyapatite. , 2001, Journal of biomedical materials research.

[28]  Larry L. Hench,et al.  Biomaterials : an interfacial approach , 1982 .

[29]  George A. Zarb,et al.  Tissue-Integrated Prostheses: Osseointegration in Clinical Dentistry , 1985 .

[30]  Miss A.O. Penney (b) , 1974, The New Yale Book of Quotations.

[31]  Takashi Nakamura,et al.  Biology of alkali- and heat-treated titanium implants. , 2003, Journal of biomedical materials research. Part A.

[32]  J. Matinlinna,et al.  Characterization of siloxane films on titanium substrate derived from three aminosilanes , 2004 .

[33]  K Nakanishi,et al.  The role of hydrated silica, titania, and alumina in inducing apatite on implants. , 1994, Journal of biomedical materials research.

[34]  K. Anselme,et al.  Osteoblast adhesion on biomaterials. , 2000, Biomaterials.