Analysis of specific gene mutations in the transforming growth factor-beta signal transduction pathway in human ovarian cancer.
暂无分享,去创建一个
N. Wake | S. Takenoshita | T. Kanuma | D. Wang | H. Mizunuma | Y. Ibuki | D Wang | T Kanuma | H Mizunuma | F Takama | Y Ibuki | N Wake | A Mogi | Y Shitara | S Takenoshita | Dan Wang | Y. Shitara | F. Takama | A. Mogi | Hideki Mizunuma | Seiichi Takenoshita
[1] Scott E. Kern,et al. Evaluation of candidate tumour suppressor genes on chromosome 18 in colorectal cancers , 1996, Nature Genetics.
[2] C. J. Gimeno,et al. Vascular MADs: two novel MAD-related genes selectively inducible by flow in human vascular endothelium. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[3] C. Harris,et al. Absence of mutations in the transforming growth factor-beta type II receptor in sporadic lung cancers with microsatellite instability and rare H-ras1 alleles. , 1997, Carcinogenesis.
[4] Scott E. Kern,et al. DPC4, A Candidate Tumor Suppressor Gene at Human Chromosome 18q21.1 , 1996, Science.
[5] Irene L Andrulis,et al. MADR2 Maps to 18q21 and Encodes a TGFβ–Regulated MAD–Related Protein That Is Functionally Mutated in Colorectal Carcinoma , 1996, Cell.
[6] Chung Lee,et al. Genetic change in transforming growth factor β (TGF-β) receptor type I gene correlates with insensitivity to TGF-β1 in human prostate cancer cells , 1996 .
[7] Kathleen R. Cho,et al. DPC4 gene in various tumor types. , 1996, Cancer research.
[8] W Godolphin,et al. Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer. , 1989, Science.
[9] T. Enomoto,et al. Mutational analysis of the transforming growth factor beta receptor type II gene in human ovarian carcinoma. , 1998, Cancer research.
[10] J. Massagué. TGFβ Signaling: Receptors, Transducers, and Mad Proteins , 1996, Cell.
[11] C. Garrett,et al. Protooncogene amplification and tumor ploidy in human ovarian neoplasms. , 1990, Human pathology.
[12] P. Hoodless,et al. MADR1, a MAD-Related Protein That Functions in BMP2 Signaling Pathways , 1996, Cell.
[13] M. Reiss,et al. Mutant p53 tumor suppressor gene causes resistance to transforming growth factor beta 1 in murine keratinocytes. , 1993, Cancer research.
[14] J. Wrana,et al. The MAD-Related Protein Smad7 Associates with the TGFβ Receptor and Functions as an Antagonist of TGFβ Signaling , 1997, Cell.
[15] M. Garcia-Blanco,et al. A mutational analysis of the polypyrimidine tract of introns. Effects of sequence differences in pyrimidine tracts on splicing. , 1993, The Journal of biological chemistry.
[16] J. Manley,et al. The role of the polypyrimidine stretch at the SV40 early pre‐mRNA 3′ splice site in alternative splicing. , 1988, The EMBO journal.
[17] K. Kinzler,et al. Microsatellite instability and mutations of the transforming growth factor beta type II receptor gene in colorectal cancer. , 1995, Cancer research.
[18] R. Derynck,et al. Receptor-associated Mad homologues synergize as effectors of the TGF-β response , 1996, Nature.
[19] K. Miyazono,et al. Enhanced expression of transforming growth factor‐β and its type‐I and type‐II receptors in human glioblastoma , 1995, International journal of cancer.
[20] M. Modan,et al. Possible role of mumps virus in the etiology of ovarian cancer , 1979, Cancer.
[21] J. Massagué,et al. Partnership between DPC4 and SMAD proteins in TGF-β signalling pathways , 1996, Nature.
[22] R. Bast,et al. Overexpression of HER-2/neu is associated with poor survival in advanced epithelial ovarian cancer. , 1990, Cancer research.
[23] Medicine,et al. Overexpression and mutation of p53 in epithelial ovarian cancer. , 1991, Cancer research.
[24] E. Wynder,et al. International comparisons of mortality rates for cancer of the breast, ovary, prostate, and colon, and per capita food consumption , 1986 .
[25] S. Thorgeirsson,et al. Induction of p53 and Bax during TGF-beta 1 initiated apoptosis in rat liver epithelial cells. , 1998, Biochemical and biophysical research communications.
[26] P. Norton,et al. Polypyrimidine tract sequences direct selection of alternative branch sites and influence protein binding. , 1994, Nucleic acids research.
[27] J. Yokota,et al. Mutation analysis of coding sequences of the entire transforming growth factor beta type II receptor gene in sporadic human colon cancer using genomic DNA and Intron primers , 1997, Oncogene.
[28] P. Hoodless,et al. MADR2 Is a Substrate of the TGFβ Receptor and Its Phosphorylation Is Required for Nuclear Accumulation and Signaling , 1996, Cell.
[29] I. Andersson,et al. Reexamination of the Three-Dimensional Structure of the Small Subunit of RuBisCo from Higher Plants , 1989, Science.
[30] Robert F. RoscignoSBlI,et al. A Mutational Analysis of the Polypyrimidine Tract of Introns , 1993 .
[31] Kathleen R. Cho,et al. A transforming growth factor beta receptor type II gene mutation common in colon and gastric but rare in endometrial cancers with microsatellite instability. , 1995, Cancer research.
[32] A. Harris. Mutant p53—the commonest genetic abnormality in human cancer? , 1990, The Journal of pathology.
[33] D. Kingsley,et al. The TGF-beta superfamily: new members, new receptors, and new genetic tests of function in different organisms. , 1994, Genes & development.
[34] H. Yokozaki,et al. Expression of TGF‐β and procollagen type I and type III in human gastric carcinomas , 1989 .
[35] K. Hatch,et al. Oncogene alterations in endometrial carcinoma. , 1990, Gynecologic oncology.
[36] P Chambon,et al. Isolation of high-molecular-weight DNA from mammalian cells. , 1973, European journal of biochemistry.
[37] T. Moody,et al. Transforming growth factor-beta receptors in human cancer cell lines: analysis of transcript, protein and proliferation. , 1997, Anticancer research.
[38] K. Kinzler,et al. Frequency of Smad gene mutations in human cancers. , 1997, Cancer research.
[39] H. Lodish,et al. Loss of functional cell surface transforming growth factor β (TGF-β) type 1 receptor correlates with insensitivity to TGF-β in chronic lymphocytic leukemia , 1997 .
[40] K. Kinzler,et al. Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability. , 1995, Science.
[41] T. Mitsudomi,et al. Somatic in vivo alterations of the DPC4 gene at 18q21 in human lung cancers. , 1996, Cancer research.
[42] D. Longo,et al. COSMETIC TALC AND OVARIAN CANCER , 1979, The Lancet.
[43] R. Bast,et al. Regulation of apoptosis in normal and malignant ovarian epithelial cells by transforming growth factor beta. , 1995, Cancer research.
[44] S. Takenoshita,et al. Mutation of the transforming growth factor-beta type II receptor gene is a rare event in human sporadic gastric carcinomas. , 1998, International journal of oncology.
[45] J. Yokota,et al. Mutation analysis of the Smad2 gene in human colon cancers using genomic DNA and intron primers. , 1998, Carcinogenesis.