Homeobox genes and orofacial development.

The discovery of the homeobox as a highly conserved DNA-binding motif found in homeotic and other genes involved in the control of Drosophila development has dramatically changed developmental biology. It has now become clear that whereas morphologically Drosophila and mammalian embryos develop very differently, the genetic control of their development has many similarities.

[1]  R. Pedersen,et al.  Cell fate and cell lineage in the endoderm of the presomite mouse embryo, studied with an intracellular tracer. , 1986, Developmental biology.

[2]  M. Ferguson,et al.  Hox-7 expression during murine craniofacial development. , 1991, Development.

[3]  M. Gulisano,et al.  Nested expression domains of four homeobox genes in developing rostral brain , 1992, Nature.

[4]  T. Martin,et al.  Parathyroid hormone-related protein: biochemistry and molecular biology. , 1991, Critical reviews in biochemistry and molecular biology.

[5]  M. Capecchi,et al.  Regionally restricted developmental defects resulting from targeted disruption of the mouse homeobox gene hox-1.5 , 1991, Nature.

[6]  R. Krumlauf,et al.  Hoxb-4 (Hox-2.6) mutant mice show homeotic transformation of a cervical vertebra and defects in the closure of the sternal rudiments , 1993, Cell.

[7]  R. Pedersen,et al.  Cell fate, morphogenetic movement and population kinetics of embryonic endoderm at the time of germ layer formation in the mouse. , 1987, Development.

[8]  E. D. De Robertis,et al.  Expression of the mouse goosecoid gene during mid-embryogenesis may mark mesenchymal cell lineages in the developing head, limbs and body wall. , 1993, Development.

[9]  I. Thesleff,et al.  Identification of BMP-4 as a signal mediating secondary induction between epithelial and mesenchymal tissues during early tooth development , 1993, Cell.

[10]  J. Rubenstein,et al.  The mouse Dlx-2 (Tes-1) gene is expressed in spatially restricted domains of the forebrain, face and limbs in midgestation mouse embryos , 1993, Mechanisms of Development.

[11]  Pierre Chambon,et al.  A homeotic transformation is generated in the rostral branchial region of the head by disruption of Hoxa-2, which acts as a selector gene , 1993, Cell.

[12]  I. Thesleff,et al.  Cell surface proteoglycan expression correlates with epithelial-mesenchymal interaction during tooth morphogenesis. , 1988, Developmental biology.

[13]  D. Noden.  Interactions and fates of avian craniofacial mesenchyme. , 1988, Development.

[14]  E. Robertis,et al.  The homeobox gene goosecoid and the origin of organizer cells in the early chick blastoderm , 1993, Cell.

[15]  M. Ferguson,et al.  Epithelial-mesenchymal interactions are required for msx 1 and msx 2 gene expression in the developing murine molar tooth. , 1993, Development.

[16]  M. Ferguson,et al.  Expression patterns of the homeobox gene, Hox-8, in the mouse embryo suggest a role in specifying tooth initiation and shape. , 1992, Development.

[17]  B. Orban.  Dental histology and embryology , 1928 .

[18]  S. Fraser,et al.  Segmentation in the chick embryo hindbrain is defined by cell lineage restrictions , 1990, Nature.

[19]  W. McGinnis,et al.  Distal-less is a downstream gene of Deformed required for ventral maxillary identity. , 1993, Development.

[20]  S. Wray,et al.  Spatially restricted expression of a member of a new family of murine Distal-less homeobox genes in the developing forebrain. , 1991, The New biologist.

[21]  R. Maas,et al.  Msx1 deficient mice exhibit cleft palate and abnormalities of craniofacial and tooth development , 1994, Nature Genetics.

[22]  K. Kaestner,et al.  Postimplantation expression patterns indicate a role for the mouse forkhead/HNF-3 alpha, beta and gamma genes in determination of the definitive endoderm, chordamesoderm and neuroectoderm. , 1993, Development.

[23]  H. Jäckle,et al.  Distal-less encodes a homoeodomain protein required for limb development in Drosophila , 1989, Nature.

[24]  R. Krumlauf,et al.  Deciphering the Hox code: Clues to patterning branchial regions of the head , 1991, Cell.

[25]  Ken W. Y. Cho,et al.  Gastrulation in the mouse: The role of the homeobox gene goosecoid , 1992, Cell.

[26]  Luis Puelles,et al.  Expression patterns of homeobox and other putative regulatory genes in the embryonic mouse forebrain suggest a neuromeric organization , 1993, Trends in Neurosciences.

[27]  M. Justice,et al.  A new family of mouse homeo box-containing genes: molecular structure, chromosomal location, and developmental expression of Hox-7.1. , 1989, Genes & development.

[28]  D M Noden,et al.  Patterning of avian craniofacial muscles. , 1986, Developmental biology.

[29]  D. Duboule,et al.  The structural and functional organization of the murine HOX gene family resembles that of Drosophila homeotic genes. , 1989, The EMBO journal.

[30]  D. Duboule,et al.  A mouse gene related to Distal-less shows a restricted expression in the developing forebrain , 1991, Nature.

[31]  R. Krumlauf,et al.  Patterning the vertebrate head: murine Hox 2 genes mark distinct subpopulations of premigratory and migrating cranial neural crest. , 1991, Development.

[32]  M. Capecchi,et al.  Mice homozygous for a targeted disruption of Hoxd-3 (Hox-4.1) exhibit anterior transformations of the first and second cervical vertebrae, the atlas and the axis. , 1993, Development.

[33]  P. Chambon,et al.  Disruption of the Hox-1.6 homeobox gene results in defects in a region corresponding to its rostral domain of expression , 1991, Cell.

[34]  B. Jacq,et al.  Hox‐7, a mouse homeobox gene with a novel pattern of expression during embryogenesis. , 1989, The EMBO journal.

[35]  D. Duboule,et al.  Homoeobox gene expression in mouse embryos varies with position by the primitive streak stage , 1986, Nature.

[36]  Edoardo Boncinelli,et al.  A distinct Hox code for the branchial region of the vertebrate head , 1991, Nature.

[37]  V. Prince,et al.  Hoxa-2 expression in normal and transposed rhombomeres: independent regulation in the neural tube and neural crest. , 1994, Development.

[38]  P. Brûlet,et al.  Homeosis in the mouse induced by a null mutation in the Hox-3.1 gene , 1992, Cell.

[39]  P. Sharpe,et al.  Expression of a human homeobox-containing gene is regulated by 1,25(OH)2D3 in bone cells. , 1993, Biochimica et biophysica acta.

[40]  P. Holland.  Problems and paradigms: Hoemeobox genes in vertebrate evolution , 1992 .

[41]  M. Scott.  Vertebrate homeobox gene nomenclature , 1992, Cell.

[42]  R. Krumlauf,et al.  The murine and Drosophila homeobox gene complexes have common features of organization and expression , 1989, Cell.

[43]  D M Noden,et al.  The role of the neural crest in patterning of avian cranial skeletal, connective, and muscle tissues. , 1983, Developmental biology.

[44]  D. Jacobs,et al.  Deformed autoregulatory element from Drosophila functions in a conserved manner in transgenic mice , 1992, Nature.

[45]  Ken W. Y. Cho,et al.  Molecular nature of Spemann's organizer: the role of the Xenopus homeobox gene goosecoid , 1991, Cell.

[46]  M. Ferguson,et al.  The homeobox gene Hox 7.1 has specific regional and temporal expression patterns during early murine craniofacial embryogenesis, especially tooth development in vivo and in vitro. , 1991, Development.

[47]  J. Rossant,et al.  The formation and maintenance of the definitive endoderm lineage in the mouse: involvement of HNF3/forkhead proteins. , 1993, Development.

[48]  R. Balling,et al.  Craniofacial abnormalities induced by ectopic expression of the homeobox gene Hox-1.1 in transgenic mice , 1989, Cell.

[49]  Andrew P. McMahon,et al.  Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity , 1993, Cell.

[50]  C. Stern,et al.  Segmental organization of embryonic diencephalon , 1993, Nature.

[51]  J. Rubenstein,et al.  Isolation and characterization of a novel cDNA clone encoding a homeodomain that is developmentally regulated in the ventral forebrain , 1991, Neuron.

[52]  M. Capecchi,et al.  Developmental defects of the ear, cranial nerves and hindbrain resulting from targeted disruption of the mouse homeobox geneHox-#150;1.6 , 1992, Nature.

[53]  Moisés Mallo,et al.  Hoxa-2 mutant mice exhibit homeotic transformation of skeletal elements derived from cranial neural crest , 1993, Cell.