Spinocerebellar Ataxia Patient Perceptions Regarding Reproductive Options

In vitro fertilization with preimplantation genetic testing is a growing reproductive option for people who want to avoid passing a single‐gene condition on to their offspring. The spinocerebellar ataxias are a group of rare, autosomal‐dominant neurodegenerative disorders which are strong candidates for the use of this technology.

[1]  G. De Michele,et al.  The Multiple Faces of Spinocerebellar Ataxia type 2 , 2017, Annals of clinical and translational neurology.

[2]  S. Domchek,et al.  Reproductive Decision-Making in Women with BRCA1/2 Mutations , 2017, Journal of Genetic Counseling.

[3]  D. Gale,et al.  Attitudes in Patients with Autosomal Dominant Polycystic Kidney Disease Toward Prenatal Diagnosis and Preimplantation Genetic Diagnosis. , 2016, Genetic testing and molecular biomarkers.

[4]  P. Gong,et al.  Impact of Huntington Disease Gene-Positive Status on Pre-Symptomatic Young Adults and Recommendations for Genetic Counselors , 2016, Journal of Genetic Counseling.

[5]  P. Murali Doraiswamy,et al.  Preimplantation genetic diagnosis for inherited neurological disorders , 2014, Nature Reviews Neurology.

[6]  Paula Coutinho,et al.  The Global Epidemiology of Hereditary Ataxia and Spastic Paraplegia: A Systematic Review of Prevalence Studies , 2014, Neuroepidemiology.

[7]  K. Bushara.  We cannot cure ataxia,we can only eradicate it. , 2013, JAMA neurology.

[8]  S. C. Collins.  Preimplantation genetic diagnosis: technical advances and expanding applications , 2013, Current opinion in obstetrics & gynecology.

[9]  D. Rosenblatt,et al.  Experience over fifteen years with a protocol for predictive testing for Huntington disease. , 2011, Molecular genetics and metabolism.

[10]  H. Paulson,et al.  The spinocerebellar ataxias. , 2009, Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society.

[11]  N. Aaronson,et al.  Attitude towards pre-implantation genetic diagnosis for hereditary cancer , 2009, Familial Cancer.

[12]  Lindsey M. King,et al.  Attitudes of high-risk women toward preimplantation genetic diagnosis. , 2009, Fertility and sterility.

[13]  Z. Alfirevic,et al.  Procedure-Related Complications of Amniocentesis and Chorionic Villous Sampling: A Systematic Review , 2007, Obstetrics and gynecology.

[14]  E. Stoffel,et al.  Attitudes Toward Prenatal Genetic Testing in Patients With Familial Adenomatous Polyposis , 2007, The American Journal of Gastroenterology.

[15]  G. Rea,et al.  Reproductive decision making before and after predictive testing for Huntington's disease: an Australian perspective , 2005, Clinical genetics.

[16]  H. Hendriks,et al.  Age at onset variance analysis in spinocerebellar ataxias: A study in a Dutch–French cohort , 2005, Annals of neurology.

[17]  B. Fernandez,et al.  Predictive, pre‐natal and diagnostic genetic testing for Huntington's disease: the experience in Canada from 1987 to 2000 , 2003, Clinical genetics.

[18]  J. Savulescu,et al.  Issues and concerns of couples presenting for preimplantation genetic diagnosis (PGD) , 2002, Prenatal diagnosis.

[19]  P. Harper,et al.  Prenatal testing for Huntington's disease: experience within the UK 1994-1998 , 2001, Journal of medical genetics.

[20]  M. Losekoot,et al.  Experience in prenatal testing for Huntington's disease in The Netherlands: procedures, results and guidelines (1987–1997) , 1999, Prenatal diagnosis.

[21]  J. M. Green,et al.  Preimplantation diagnosis and other reproductive options: attitudes of male and female carriers of recessive disorders. , 1997, Human reproduction.

[22]  Í. Lopes-Cendes,et al.  Correlation between CAG repeat length and clinical features in Machado-Joseph disease. , 1995, American journal of human genetics.

[23]  J. Penney,et al.  At-risk persons' attitudes toward presymptomatic and prenatal testing of Huntington disease in Michigan. , 1987, American journal of medical genetics.

[24]  C. Moutou,et al.  ESHRE PGD Consortium data collection XIII: cycles from January to December 2010 with pregnancy follow-up to October 2011. , 2015, Human reproduction.

[25]  C. Moutou,et al.  ESHRE PGD Consortium data collection XII: cycles from January to December 2009 with pregnancy follow-up to October 2010. , 2014, Human reproduction.

[26]  C. Moutou,et al.  ESHRE PGD Consortium data collection XI: cycles from January to December 2008 with pregnancy follow-up to October 2009. , 2012, Human reproduction.

[27]  C. Moutou,et al.  ESHRE PGD Consortium data collection X: cycles from January to December 2007 with pregnancy follow-up to October 2008. , 2010, Human reproduction.

[28]  C. Moutou,et al.  ESHRE PGD Consortium data collection IX: cycles from January to December 2006 with pregnancy follow-up to October 2007. , 2009, Human reproduction.

[29]  C. Moutou,et al.  ESHRE PGD Consortium data collection VIII: cycles from January to December 2005 with pregnancy follow-up to October 2006. , 2008, Human reproduction.

[30]  C. Moutou,et al.  ESHRE PGD consortium data collection VII: cycles from January to December 2004 with pregnancy follow-up to October 2005. , 2008, Human reproduction.

[31]  K. Vesela,et al.  ESHRE PGD Consortium data collection VI: cycles from January to December 2003 with pregnancy follow-up to October 2004. , 2007, Human reproduction.

[32]  A. Dürr,et al.  Prenatal testing for Huntington's disease: a European collaborative study , 2002, European Journal of Human Genetics.