Real‐time confocal laser endomicroscopic evaluation of primary liver cancer based on human liver autofluorescence

Confocal laser endomicroscopy (CLE) is available for real‐time microscopic examination. This study aims to evaluate the usefulness of intraoperative CLE examination as a modality to evaluate surgical margins in surgery for primary liver cancer.

[1]  Y. Doki,et al.  A novel approach of optical biopsy using probe-based confocal laser endomicroscopy for peritoneal metastasis , 2016, Surgical Endoscopy.

[2]  B. Gayet,et al.  Usefulness of Intraoperative Real-Time Tissue Elastography During Laparoscopic Hepatectomy. , 2015, Journal of the American College of Surgeons.

[3]  N. Kokudo,et al.  Usefulness of indocyanine green‐fluorescence imaging during laparoscopic hepatectomy to visualize subcapsular hard‐to‐identify hepatic malignancy , 2015, Journal of surgical oncology.

[4]  B. Wiedenmann,et al.  Near-Infrared Confocal Laser Endomicroscopy Detects Colorectal Cancer via an Integrin αvβ3 Optical Probe , 2015, Molecular Imaging and Biology.

[5]  Guido Costamagna,et al.  Use of probe-based confocal laser endomicroscopy (pCLE) in gastrointestinal applications. A consensus report based on clinical evidence , 2015, United European gastroenterology journal.

[6]  S. Schmidt,et al.  Portal uptake function in veno-occlusive regions evaluated by real-time fluorescent imaging using indocyanine green , 2013 .

[7]  M. Wallace,et al.  Miami classification for probe-based confocal laser endomicroscopy , 2011, Endoscopy.

[8]  J. Belghiti,et al.  Oncologic Resection for Malignant Tumors of the Liver , 2011, Annals of surgery.

[9]  A. Mennone,et al.  Needle-based confocal laser endomicroscopy to assess liver histology in vivo. , 2011, Gastrointestinal endoscopy.

[10]  M. Wallace,et al.  Optimal fluorescein dose for intravenous application in miniprobe‐based confocal laser scanning microscopy in pigs , 2011, Journal of biophotonics.

[11]  Michael Vieth,et al.  Near-infrared confocal imaging during mini-laparoscopy: a novel rigid endomicroscope with increased imaging plane depth. , 2010, Journal of hepatology.

[12]  Giovanni Bottiroli,et al.  Human liver autofluorescence: An intrinsic tissue parameter discriminating normal and diseased conditions , 2010, Lasers in surgery and medicine.

[13]  Takeaki Ishizawa,et al.  Real‐time identification of liver cancers by using indocyanine green fluorescent imaging , 2009, Cancer.

[14]  Alexander Meining,et al.  Intravenous application of fluorescein for confocal laser scanning microscopy: evaluation of contrast dynamics and image quality with increasing injection-to-imaging time. , 2008, Gastrointestinal endoscopy.

[15]  R. Kiesslich,et al.  In vivo confocal laser endomicroscopy of the human liver: a novel method for assessing liver microarchitecture in real time. , 2008, Endoscopy.

[16]  Ken Hayashi,et al.  Image-Guided Liver Mapping Using Fluorescence Navigation System with Indocyanine Green for Anatomical Hepatic Resection , 2008, World Journal of Surgery.

[17]  A. Polglase,et al.  Confocal laser endoscopy for diagnosing intraepithelial neoplasias and colorectal cancer in vivo. , 2004, Gastroenterology.

[18]  S. Futagawa,et al.  Relationship between the histological degrees of hepatitis and the postoperative recurrence of hepatocellular carcinoma in patients with hepatitis C. , 2002, Hepatology research : the official journal of the Japan Society of Hepatology.

[19]  R. Kimura.  Hyperfluorescent dots in the ciliary body band in patients with granulomatous uveitis. , 1982, The British journal of ophthalmology.

[20]  Hiroshi Imamura,et al.  Intraoperative fluorescent cholangiography using indocyanine green: a biliary road map for safe surgery. , 2009, Journal of the American College of Surgeons.

[21]  Michael Vieth,et al.  In vivo confocal laser laparoscopy allows real time subsurface microscopy in animal models of liver disease. , 2008, Journal of hepatology.