Relocation of p25α/tubulin polymerization promoting protein from the nucleus to the perinuclear cytoplasm in the oligodendroglia of sporadic and COQ2 mutant multiple system atrophy

[1]  S. Archer Mitochondrial dynamics--mitochondrial fission and fusion in human diseases. , 2013, The New England journal of medicine.

[2]  G. López-Doménech,et al.  Mitochondrial trafficking in neurons and the role of the Miro family of GTPase proteins. , 2013, Biochemical Society transactions.

[3]  M. Iijima,et al.  Mitochondrial dynamics in neurodegeneration. , 2013, Trends in cell biology.

[4]  Q. Lu,et al.  Phosphorylated olig1 localizes to the cytosol of oligodendrocytes and promotes membrane expansion and maturation , 2012, Glia.

[5]  Y. Itoyama,et al.  Suppression of dynamin GTPase decreases α-synuclein uptake by neuronal and oligodendroglial cells: a potent therapeutic target for synucleinopathy , 2012, Molecular Neurodegeneration.

[6]  J. Ovádi,et al.  Zn²+-induced rearrangement of the disordered TPPP/p25 affects its microtubule assembly and GTPase activity. , 2011, Biochemistry.

[7]  J. Ovádi,et al.  Disordered TPPP/p25 binds GTP and displays Mg2+‐dependent GTPase activity , 2011, FEBS letters.

[8]  Y. Itoyama,et al.  Role of TPPP/p25 on α-synuclein-mediated oligodendroglial degeneration and the protective effect of SIRT2 inhibition in a cellular model of multiple system atrophy , 2010, Neurochemistry International.

[9]  H. Budka,et al.  Tubulin polymerization promoting protein (TPPP/p25) as a marker for oligodendroglial changes in multiple sclerosis , 2010, Glia.

[10]  J. Ovádi,et al.  Tubulin polymerization‐promoting protein (TPPP/p25) is critical for oligodendrocyte differentiation , 2010, Glia.

[11]  R. Dolmetsch,et al.  The carboxy-terminal fragment of α1A calcium channel preferentially aggregates in the cytoplasm of human spinocerebellar ataxia type 6 Purkinje cells , 2009, Acta Neuropathologica.

[12]  M. Tomita,et al.  Systematic identification of cell cycle-dependent yeast nucleocytoplasmic shuttling proteins by prediction of composite motifs (Proceedings of the National Academy of Sciences of the United States of America (2009) 106, (10171-10176) DOI: 10.1073/pnas.0900604106) , 2009 .

[13]  M. Tomita,et al.  Systematic identification of cell cycle-dependent yeast nucleocytoplasmic shuttling proteins by prediction of composite motifs , 2009, Proceedings of the National Academy of Sciences.

[14]  J. Ovádi,et al.  An unstructured protein with destructive potential: TPPP/p25 in neurodegeneration , 2009, BioEssays : news and reviews in molecular, cellular and developmental biology.

[15]  C. Richter-Landsberg,et al.  α-Synuclein Aggregation and Ser-129 Phosphorylation-dependent Cell Death in Oligodendroglial Cells* , 2009, Journal of Biological Chemistry.

[16]  G. Halliday,et al.  LRRK2 and parkin immunoreactivity in multiple system atrophy inclusions , 2008, Acta Neuropathologica.

[17]  K. Jellinger,et al.  Multiple system atrophy: A primary oligodendrogliopathy , 2008, Annals of neurology.

[18]  B. Sarcevic,et al.  The phosphorylation of p25/TPPP by LIM kinase 1 inhibits its ability to assemble microtubules. , 2007, Experimental cell research.

[19]  P. Højrup,et al.  p25α Relocalizes in Oligodendroglia from Myelin to Cytoplasmic Inclusions in Multiple System Atrophy , 2007 .

[20]  I. Kanazawa,et al.  Multiplex families with multiple system atrophy. , 2007, Archives of neurology.

[21]  Ryan E. Mills,et al.  Classical Nuclear Localization Signals: Definition, Function, and Interaction with Importin α* , 2007, Journal of Biological Chemistry.

[22]  H. Budka,et al.  The brain-specific protein TPPP/p25 in pathological protein deposits of neurodegenerative diseases , 2007, Acta Neuropathologica.

[23]  H. Budka,et al.  TPPP/p25 in brain tumours: expression in non-neoplastic oligodendrocytes but not in oligodendroglioma cells , 2007, Acta Neuropathologica.

[24]  J. Ovádi,et al.  Interaction of TPPP/p25 protein with glyceraldehyde‐3‐phosphate dehydrogenase and their co‐localization in Lewy bodies , 2006, FEBS letters.

[25]  T. Moos,et al.  P25α/Tubulin polymerization promoting protein expression by myelinating oligodendrocytes of the developing rat brain , 2006 .

[26]  J. Holton,et al.  PINK1 protein in normal human brain and Parkinson's disease. , 2006, Brain : a journal of neurology.

[27]  X. Shen,et al.  SUMO-1 marks subdomains within glial cytoplasmic inclusions of multiple system atrophy , 2005, Neuroscience Letters.

[28]  Daniel Otzen,et al.  p25α Stimulates α-Synuclein Aggregation and Is Co-localized with Aggregated α-Synuclein in α-Synucleinopathies* , 2005, Journal of Biological Chemistry.

[29]  H. Budka,et al.  Natively unfolded tubulin polymerization promoting protein TPPP/p25 is a common marker of alpha-synucleinopathies , 2004, Neurobiology of Disease.

[30]  J Ovádi,et al.  TPPP/p25 promotes tubulin assemblies and blocks mitotic spindle formation , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[31]  J. Kovács,et al.  Brain-specific p25 protein binds to tubulin and microtubules and induces aberrant microtubule assemblies at substoichiometric concentrations. , 2002, Biochemistry.

[32]  T. Littlewood,et al.  Molecular mechanism of translocation through nuclear pore complexes during nuclear protein import , 2001, FEBS letters.

[33]  J. Trojanowski,et al.  α‐synuclein is developmentally expressed in cultured rat brain oligodendrocytes , 2000, Journal of neuroscience research.

[34]  Shigeo Hirai,et al.  NACP/α-synuclein immunoreactivity in fibrillary components of neuronal and oligodendroglial cytoplasmic inclusions in the pontine nuclei in multiple system atrophy , 1998, Acta Neuropathologica.

[35]  J Q Trojanowski,et al.  Glial cytoplasmic inclusions in white matter oligodendrocytes of multiple system atrophy brains contain insoluble α‐synuclein , 1998, Annals of neurology.

[36]  P. Blumbergs,et al.  Multiple-system atrophy: a new α-synuclein disease? , 1998, The Lancet.

[37]  Nigel J. Cairns,et al.  Filamentous α-synuclein inclusions link multiple system atrophy with Parkinson's disease and dementia with Lewy bodies , 1998, Neuroscience Letters.

[38]  Hitoshi Takahashi,et al.  α-Synuclein immunoreactivity in glial cytoplasmic inclusions in multiple system atrophy , 1998, Neuroscience Letters.

[39]  M. Berry,et al.  Biochemical subtypes of oligodendrocyte in the anterior medullary velum of the rat as revealed by the monoclonal antibody rip , 1995, Glia.

[40]  K. Imahori,et al.  A novel brain‐specific 25 kDa protein (p25) is phosphorylated by a Ser/Thr‐Pro kinase (TPK II) from tau protein kinase fractions , 1991, FEBS letters.

[41]  H. Yamaguchi,et al.  Oligodendroglial Microtubular Tangles in Olivopontocerebellar Atrophy , 1990, Journal of neuropathology and experimental neurology.

[42]  Peter L. Lantos,et al.  Glial cytoplasmic inclusions in the CNS of patients with multiple system atrophy (striatonigral degeneration, olivopontocerebellar atrophy and Shy-Drager syndrome) , 1989, Journal of the Neurological Sciences.

[43]  太田 浄文 Relocation of p25α/tubulin polymerization promoting protein from the nucleus to the perinuclear cytoplasm in the oligodendroglia of sporadic and COQ2 mutant multiple system atrophy , 2014 .

[44]  J. Trojanowski,et al.  Mutations in COQ2 in familial and sporadic multiple-system atrophy. , 2013, The New England journal of medicine.

[45]  P. Højrup,et al.  p25alpha relocalizes in oligodendroglia from myelin to cytoplasmic inclusions in multiple system atrophy. , 2007, The American journal of pathology.

[46]  T. Moos,et al.  P25alpha/Tubulin polymerization promoting protein expression by myelinating oligodendrocytes of the developing rat brain. , 2006, Journal of neurochemistry.

[47]  P. Blumbergs,et al.  Multiple-system atrophy: a new alpha-synuclein disease? , 1998, Lancet.

[48]  R A Crowther,et al.  Filamentous alpha-synuclein inclusions link multiple system atrophy with Parkinson's disease and dementia with Lewy bodies. , 1998, Neuroscience letters.

[49]  K. Arima,et al.  NACP/alpha-synuclein immunoreactivity in fibrillary components of neuronal and oligodendroglial cytoplasmic inclusions in the pontine nuclei in multiple system atrophy. , 1998, Acta neuropathologica.

[50]  S. Tsuji,et al.  Alpha-synuclein immunoreactivity in glial cytoplasmic inclusions in multiple system atrophy. , 1998, Neuroscience letters.