A computer system to assist in the evaluation of the EEGs of epileptic patients

The specific EEG manifestations of epilepsy, seizures, and interictal spikes and sharp waves occur at unpredictable times and at variable frequencies. To obtain an adequate diagnosis, it is often necessary to record the EEG for several hours or several days. A computer system was developed to perform data reduction and quantification by continuously monitoring seizures and automatically recognizing interictal spikes and sharp waves. The past 2 min of EEG are kept on the computer disk at every instant. When an epileptic seizure occurs or when a spike is detected, a sample of EEG, including a section preceding the event itself, is written on the EEG polygraph and on magnetic tape. A continuous recording is thus replaced by samples of varying lengths, containing only the important aspects of the EEG, reducing considerably the original data. After the monitoring session, the spatial and temporal distributions of the interictal activity are presented in a quantified form on the terminal. The seizures are recorded on digital tape and are available for several types of processing. The patient is also monitored by a video system; EEG and video are synchronized by a time-of-day clock to allow electroclinical correlations.

[1]  M. Brazier Spread of seizure discharges in epilepsy: anatomical and electrophysiological considerations. , 1972, Experimental neurology.

[2]  A.S. Gevins,et al.  Automated analysis of the electrical activity of the human brain (EEG): A progress report , 1975, Proceedings of the IEEE.

[3]  J R Ives,et al.  Seizure moitoring: a new tool in electroencephalography. , 1976, Electroencephalography and clinical neurophysiology.

[4]  J Gotman,et al.  A quantitative comparison of traditional reading of the EEG and interpretation of computer-extracted features in patients with supratentorial brain lesions. , 1975, Electroencephalography and clinical neurophysiology.

[5]  W. R. Adey,et al.  Contamination of scalp EEG spectrum during contraction of cranio-facial muscles. , 1974, Electroencephalography and clinical neurophysiology.

[6]  J Gotman,et al.  Comparison of traditional reading of the EEG and automatic recognition of interictal epileptic activity. , 1978, Electroencephalography and clinical neurophysiology.

[7]  John S. Barlow,et al.  Computerized Clinical Electroencephalography in Perspective , 1979, IEEE Transactions on Biomedical Engineering.

[8]  J R Ives,et al.  Clinical applications of spectral analysis and extraction of features from electroencephalograms with slow waves in adult patients. , 1973, Electroencephalography and clinical neurophysiology.

[9]  J R Ives,et al.  Automatic recognition of inter-ictal epileptic activity in prolonged EEG recordings. , 1979, Electroencephalography and clinical neurophysiology.

[10]  J. R. Cox,et al.  Digital analysis of the electroencephalogram, the blood pressure wave, and the electrocardiogram , 1972 .

[11]  J. Gotman,et al.  Automatic recognition and quantification of interictal epileptic activity in the human scalp EEG. , 1976, Electroencephalography and clinical neurophysiology.

[12]  J R Ives,et al.  A long term time-lapse video system to document the patients spontaneous clinical seizure synchronized with the EEG. , 1978, Electroencephalography and clinical neurophysiology.