Probing the hepatotoxicity mechanisms of novel chlorinated polyfluoroalkyl sulfonates to zebrafish larvae: Implication of structural specificity.

[1]  Qianqian Cui,et al.  Subchronic Hepatotoxicity Effects of 6:2 Chlorinated Polyfluorinated Ether Sulfonate (6:2 Cl-PFESA), a Novel Perfluorooctanesulfonate (PFOS) Alternative, on Adult Male Mice. , 2018, Environmental science & technology.

[2]  Yi Wang,et al.  Suspect and Nontarget Screening of Per- and Polyfluoroalkyl Substances in Wastewater from a Fluorochemical Manufacturing Park. , 2018, Environmental science & technology.

[3]  Carla A. Ng,et al.  Predicting Relative Protein Affinity of Novel Per- and Polyfluoroalkyl Substances (PFASs) by An Efficient Molecular Dynamics Approach. , 2018, Environmental science & technology.

[4]  G. Jiang,et al.  Chlorinated Polyfluorinated Ether Sulfonates Exhibit Higher Activity toward Peroxisome Proliferator-Activated Receptors Signaling Pathways than Perfluorooctanesulfonate. , 2018, Environmental science & technology.

[5]  W. Liu,et al.  Bioaccumulation and effects of novel chlorinated polyfluorinated ether sulfonate in freshwater alga Scenedesmus obliquus. , 2018, Environmental pollution.

[6]  Jerzy Leszczynski,et al.  Endocrine-disrupting activity of per- and polyfluoroalkyl substances: Exploring combined approaches of ligand and structure based modeling. , 2017, Chemosphere.

[7]  G. Jiang,et al.  Identification of Novel Hydrogen-Substituted Polyfluoroalkyl Ether Sulfonates in Environmental Matrices near Metal-Plating Facilities. , 2017, Environmental science & technology.

[8]  F. Luo,et al.  Oryzanol Modifies High Fat Diet-Induced Obesity, Liver Gene Expression Profile, and Inflammation Response in Mice. , 2017, Journal of agricultural and food chemistry.

[9]  W. Liu,et al.  Atmospheric chlorinated polyfluorinated ether sulfonate and ionic perfluoroalkyl acids in 2006 to 2014 in Dalian, China , 2017, Environmental toxicology and chemistry.

[10]  Yong Guo,et al.  6:2 Chlorinated polyfluorinated ether sulfonate, a PFOS alternative, induces embryotoxicity and disrupts cardiac development in zebrafish embryos. , 2017, Aquatic toxicology.

[11]  Yawei Wang,et al.  Chlorinated Polyfluoroalkyl Ether Sulfonic Acids in Marine Organisms from Bohai Sea, China: Occurrence, Temporal Variations, and Trophic Transfer Behavior. , 2017, Environmental science & technology.

[12]  Ian T Cousins,et al.  Levels, Isomer Profiles, and Estimated Riverine Mass Discharges of Perfluoroalkyl Acids and Fluorinated Alternatives at the Mouths of Chinese Rivers. , 2016, Environmental science & technology.

[13]  Changjiang Huang,et al.  Chronic perfluorooctane sulfonate (PFOS) exposure induces hepatic steatosis in zebrafish. , 2016, Aquatic toxicology.

[14]  Chi-Tang Ho,et al.  Ginger Essential Oil Ameliorates Hepatic Injury and Lipid Accumulation in High Fat Diet-Induced Nonalcoholic Fatty Liver Disease. , 2016, Journal of agricultural and food chemistry.

[15]  Huimin Zhao,et al.  Effects of perfluorooctane sulfonate and its alternatives on long-term potentiation in the hippocampus CA1 region of adult rats in vivo. , 2016, Toxicology research.

[16]  Yong Liang,et al.  Human Exposure and Elimination Kinetics of Chlorinated Polyfluoroalkyl Ether Sulfonic Acids (Cl-PFESAs). , 2016, Environmental science & technology.

[17]  R. Dietz,et al.  Observation of emerging per- and polyfluoroalkyl substances (PFASs) in Greenland marine mammals. , 2016, Chemosphere.

[18]  Yali Shi,et al.  Tissue Distribution and Whole Body Burden of the Chlorinated Polyfluoroalkyl Ether Sulfonic Acid F-53B in Crucian Carp (Carassius carassius): Evidence for a Highly Bioaccumulative Contaminant of Emerging Concern. , 2015, Environmental science & technology.

[19]  Shuhong Fang,et al.  In Vivo and in Vitro Isomer-Specific Biotransformation of Perfluorooctane Sulfonamide in Common Carp (Cyprinus carpio). , 2015, Environmental science & technology.

[20]  G. Perdew,et al.  Metabolomics Reveals that Aryl Hydrocarbon Receptor Activation by Environmental Chemicals Induces Systemic Metabolic Dysfunction in Mice. , 2015, Environmental science & technology.

[21]  G. Jiang,et al.  Identification of Novel Polyfluorinated Ether Sulfonates as PFOS Alternatives in Municipal Sewage Sludge in China. , 2015, Environmental science & technology.

[22]  A. Glynn,et al.  Temporal changes (1997-2012) of perfluoroalkyl acids and selected precursors (including isomers) in Swedish human serum. , 2015, Environmental pollution.

[23]  G. Jiang,et al.  PFOS induced lipid metabolism disturbances in BALB/c mice through inhibition of low density lipoproteins excretion , 2014, Scientific Reports.

[24]  Liang-Hong Guo,et al.  Structure-based investigation on the interaction of perfluorinated compounds with human liver fatty acid binding protein. , 2013, Environmental science & technology.

[25]  G. Carlsson,et al.  Comparison of developmental toxicity of seven perfluoroalkyl acids to zebrafish embryos. , 2013, Environmental toxicology and pharmacology.

[26]  Yang Yang,et al.  First report of a Chinese PFOS alternative overlooked for 30 years: its toxicity, persistence, and presence in the environment. , 2013, Environmental science & technology.

[27]  D. Melzer,et al.  Associations between PFOA, PFOS and changes in the expression of genes involved in cholesterol metabolism in humans. , 2013, Environment international.

[28]  A. Lampen,et al.  In vitro toxicological characterization of perfluorinated carboxylic acids with different carbon chain lengths. , 2013, Toxicology letters.

[29]  W. Liu,et al.  Global liver proteome analysis using iTRAQ labeling quantitative proteomic technology to reveal biomarkers in mice exposed to perfluorooctane sulfonate (PFOS). , 2012, Environmental science & technology.

[30]  J. Giesy,et al.  Characterization of a bystander effect induced by the endocrine-disrupting chemical 6-propyl-2-thiouracil in zebrafish embryos. , 2012, Aquatic toxicology.

[31]  J. Giesy,et al.  PFOS-induced hepatic steatosis, the mechanistic actions on β-oxidation and lipid transport. , 2012, Biochimica et biophysica acta.

[32]  James Franklin,et al.  Perfluoroalkyl and Polyfluoroalkyl Substances in the Environment: Terminology, Classification, and Origins , 2011, Integrated environmental assessment and management.

[33]  Scott A Mabury,et al.  A pilot survey of legacy and current commercial fluorinated chemicals in human sera from United States donors in 2009. , 2011, Environmental science & technology.

[34]  Eun-Young Kim,et al.  Transactivation potencies of the Baikal seal (Pusa sibirica) peroxisome proliferator-activated receptor α by perfluoroalkyl carboxylates and sulfonates: estimation of PFOA induction equivalency factors. , 2011, Environmental science & technology.

[35]  S. Klein,et al.  Obesity and nonalcoholic fatty liver disease: Biochemical, metabolic, and clinical implications , 2010, Hepatology.

[36]  Bingsheng Zhou,et al.  Combined effects of polyfluorinated and perfluorinated compounds on primary cultured hepatocytes from rare minnow (Gobiocypris rarus) using toxicogenomic analysis. , 2009, Aquatic toxicology.

[37]  Gary Stern,et al.  Trophodynamics of some PFCs and BFRs in a western Canadian Arctic marine food web. , 2009, Environmental science & technology.

[38]  K. Yu,et al.  Chronic effects of water-borne PFOS exposure on growth, survival and hepatotoxicity in zebrafish: a partial life-cycle test. , 2009, Chemosphere.

[39]  Kevin C Jones,et al.  A first global production, emission, and environmental inventory for perfluorooctane sulfonate. , 2009, Environmental science & technology.

[40]  C. Lau,et al.  Perfluorooctane sulfonate-induced changes in fetal rat liver gene expression. , 2008, Toxicology.

[41]  D. Knapen,et al.  Toxicity evaluation of perfluorooctane sulfonate (PFOS) in the liver of common carp (Cyprinus carpio). , 2008, Aquatic toxicology.

[42]  B. Thisse,et al.  Spatio‐temporal distribution of fatty acid‐binding protein 6 (fabp6) gene transcripts in the developing and adult zebrafish (Danio rerio) , 2008, The FEBS journal.

[43]  C. Lau,et al.  Perfluoroalkyl acids: a review of monitoring and toxicological findings. , 2007, Toxicological sciences : an official journal of the Society of Toxicology.

[44]  D. Dix,et al.  Toxicogenomic study of triazole fungicides and perfluoroalkyl acids in rat livers predicts toxicity and categorizes chemicals based on mechanisms of toxicity. , 2007, Toxicological sciences : an official journal of the Society of Toxicology.

[45]  R. Geisler,et al.  Differential gene expression as a toxicant-sensitive endpoint in zebrafish embryos and larvae. , 2007, Aquatic toxicology.

[46]  Qinglin Yang,et al.  Roles of PPARs on regulating myocardial energy and lipid homeostasis , 2007, Journal of Molecular Medicine.

[47]  John P. Vanden Heuvel,et al.  Differential Activation of Nuclear Receptors by Perfluorinated Fatty Acid Analogs and Natural Fatty Acids: A Comparison of Human, Mouse, and Rat Peroxisome Proliferator-Activated Receptor-α, -β, and -γ, Liver X Receptor-β, and Retinoid X Receptor-α , 2006 .

[48]  Derek C G Muir,et al.  Biomagnification of perfluoroalkyl compounds in the bottlenose dolphin (Tursiops truncatus) food web. , 2006, Environmental science & technology.

[49]  Béatrice Desvergne,et al.  From molecular action to physiological outputs: peroxisome proliferator-activated receptors are nuclear receptors at the crossroads of key cellular functions. , 2006, Progress in lipid research.

[50]  M. Bradbury.  Lipid metabolism and liver inflammation. I. Hepatic fatty acid uptake: possible role in steatosis. , 2006, American journal of physiology. Gastrointestinal and liver physiology.

[51]  Z. Madar,et al.  Grapefruit and oroblanco enhance hepatic detoxification enzymes in rats: possible role in protection against chemical carcinogenesis. , 2005, Journal of agricultural and food chemistry.

[52]  S. Tittlemier,et al.  Fluorinated organic compounds in an eastern Arctic marine food web. , 2004, Environmental science & technology.

[53]  S. Mabury,et al.  Perfluoroalkyl contaminants in a food web from Lake Ontario. , 2004, Environmental science & technology.

[54]  Nancy Hopkins,et al.  Identification of 315 genes essential for early zebrafish development. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[55]  David J. Waxman,et al.  trans-Activation of PPARα and Induction of PPARα Target Genes by Perfluorooctane-Based Chemicals , 2004 .

[56]  Roger G Perkins,et al.  The Toxicology of Perfluorooctanoate , 2004, Critical reviews in toxicology.

[57]  Kurunthachalam Kannan,et al.  Neuroendocrine effects of perfluorooctane sulfonate in rats. , 2003, Environmental health perspectives.

[58]  C. Lau,et al.  Exposure to perfluorooctane sulfonate during pregnancy in rat and mouse. I: maternal and prenatal evaluations. , 2003, Toxicological sciences : an official journal of the Society of Toxicology.

[59]  C. Elcombe,et al.  Sub-chronic dietary toxicity of potassium perfluorooctanesulfonate in rats. , 2003, Toxicology.

[60]  Scott A Mabury,et al.  Bioconcentration and tissue distribution of perfluorinated acids in rainbow trout (Oncorhynchus mykiss) , 2003, Environmental toxicology and chemistry.

[61]  Nathan M. Bass,et al.  Interactions of flurochemicals with rat liver fatty acid-binding protein , 2002 .

[62]  P. Angulo,et al.  Nonalcoholic fatty liver disease. , 2002, Revista de gastroenterologia de Mexico.

[63]  Scott A Mabury,et al.  Monitoring perfluorinated surfactants in biota and surface water samples following an accidental release of fire-fighting foam into Etobicoke Creek. , 2002, Environmental science & technology.

[64]  Thomas D. Schmittgen,et al.  Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. , 2001, Methods.

[65]  Janardan K. Reddy,et al.  III. Peroxisomal β-oxidation, PPARα, and steatohepatitis , 2001 .

[66]  E. Kissa,et al.  Fluorinated Surfactants and Repellents , 2001 .

[67]  J. Giesy,et al.  Global distribution of perfluorooctane sulfonate in wildlife. , 2001, Environmental science & technology.

[68]  J. Trent,et al.  Microarrays and toxicology: The advent of toxicogenomics , 1999, Molecular carcinogenesis.

[69]  W. J. Johnson,et al.  Cholesterol transport between cells and high-density lipoproteins. , 1991, Biochimica et biophysica acta.

[70]  S. Eisenberg.  Metabolism of apolipoproteins and lipoproteins , 1990 .

[71]  G. Kennedy,et al.  Increase in mouse liver weight following feeding of ammonium perfluorooctanoate and related fluorochemicals. , 1987, Toxicology letters.

[72]  Jinghua Wang,et al.  Cytotoxicity of novel fluorinated alternatives to long-chain perfluoroalkyl substances to human liver cell line and their binding capacity to human liver fatty acid binding protein , 2017, Archives of Toxicology.

[73]  T. Kong,et al.  Tributyltin promoted hepatic steatosis in zebrafish (Danio rerio) and the molecular pathogenesis involved. , 2016, Aquatic toxicology.

[74]  D. Knapen,et al.  Structure-activity relationship assessment of four perfluorinated chemicals using a prolonged zebrafish early life stage test. , 2011, Chemosphere.

[75]  A. Bonen,et al.  Membrane fatty acid transporters as regulators of lipid metabolism: implications for metabolic disease. , 2010, Physiological reviews.

[76]  Wenyue Hu,et al.  Identification of genes responsive to PFOS using gene expression profiling. , 2005, Environmental toxicology and pharmacology.

[77]  T. Suga,et al.  Induction of Cytochrome P-450 and Peroxisome Proliferation in Rat Liver by Perfluorinated Octane Sulphonic Acid (PFOS) , 1987 .