Protective effects of Zishen Huoxue recipe against neuronal injury in the neurovascular unit of rats with vascular dementia by interfering with inflammatory cascade-induced pyroptosis

[1]  Zirui Zhu,et al.  Vascular dementia: A microglia's perspective , 2022, Ageing Research Reviews.

[2]  Zhanchun Li,et al.  Neuropeptide Y and receptors are associated with the pyroptosis of nucleus pulposus in aging and degenerative intervertebral discs of rats , 2022, Neuropeptides.

[3]  S. Jose,et al.  Mechanisms of NLRP3 activation and pathology during neurodegeneration. , 2022, The international journal of biochemistry & cell biology.

[4]  Yun Zhao,et al.  Tongluo Yishen Decoction Ameliorates Renal Fibrosis via NLRP3-Mediated Pyroptosis In Vivo and In Vitro , 2022, Frontiers in Pharmacology.

[5]  Jianning Zhang,et al.  NLRP1 Inflammasomes: A Potential Target for the Treatment of Several Types of Brain Injury , 2022, Frontiers in Immunology.

[6]  Hui Yang,et al.  Luteolin Induced Hippocampal Neuronal Pyroptosis Inhibition by Regulation of miR-124-3p/TNF-α/TRAF6 Axis in Mice Affected by Breast-Cancer-Related Depression , 2022, Evidence-based complementary and alternative medicine : eCAM.

[7]  A. Ahmadiani,et al.  MicroRNA modulation is a potential molecular mechanism for neuroprotective effects of intranasal insulin administration in amyloid βeta oligomer induced Alzheimer's like rat model , 2022, Experimental Gerontology.

[8]  Shuang He,et al.  Synergy of "Yiqi" and "Huoxue" components of QishenYiqi formula in Ischemic stroke protection via lysosomal/inflammatory mechanisms. , 2022, Journal of ethnopharmacology.

[9]  Jing Ji,et al.  Progress in the Mechanism of Autophagy and Traditional Chinese Medicine Herb Involved in Dementia , 2022, Frontiers in Pharmacology.

[10]  Liping Wang,et al.  Therapeutic targets of neuroprotection and neurorestoration in ischemic stroke: Applications for natural compounds from medicinal herbs. , 2022, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[11]  Wei-Ming Ren,et al.  Zhilong Huoxue Tongyu Capsule Alleviated the Pyroptosis of Vascular Endothelial Cells Induced by ox-LDL through miR-30b-5p/NLRP3 , 2022, Evidence-based complementary and alternative medicine : eCAM.

[12]  P. Vulto,et al.  Modeling ischemic stroke in a triculture neurovascular unit on-a-chip , 2021, Fluids and Barriers of the CNS.

[13]  Lu Wang,et al.  MiR-124 Prevents the Microglial Proinflammatory Response by Inhibiting the Activities of TLR4 and Downstream NLRP3 in Palmitic Acid-Treated BV2 Cells , 2021, Journal of Molecular Neuroscience.

[14]  Liuting Zeng,et al.  Systems Biology and Chemoinformatics-Based Strategies to Explore the Biological Mechanism of Fugui Wenyang Decoction in Treating Vascular Dementia Rats , 2021, Oxidative medicine and cellular longevity.

[15]  Gege Chen,et al.  Huoxue Jiedu Huayu Formula Alleviates Cell Pyroptosis in Contralateral Kidneys of 6-Month-Old UUO Rats through the NLRP3/Caspase-1/IL-1β Pathway , 2021, Evidence-based complementary and alternative medicine : eCAM.

[16]  Clément Brunner,et al.  Location Matters: Navigating Regional Heterogeneity of the Neurovascular Unit , 2021, Frontiers in Cellular Neuroscience.

[17]  X. Bai,et al.  Traditional Chinese Medicine Intervenes in Vascular Dementia: Traditional Medicine Brings New Expectations , 2021, Frontiers in Pharmacology.

[18]  A. Strasser,et al.  Molecular mechanisms of cell death in neurological diseases , 2021, Cell Death & Differentiation.

[19]  Xinsheng Han,et al.  Inhibition of long non-coding RNA HOXA11-AS against neuroinflammation in Parkinson's disease model via targeting miR-124-3p mediated FSTL1/NF-κB axis , 2021, Aging.

[20]  Daling Zhu,et al.  Circular RNA Calm4 Regulates Hypoxia-Induced Pulmonary Arterial Smooth Muscle Cells Pyroptosis via the Circ-Calm4/miR-124-3p/PDCD6 Axis , 2021, Arteriosclerosis, thrombosis, and vascular biology.

[21]  Li Zhao,et al.  Network Pharmacology Reveals the Mechanism of Activity of Tongqiao Huoxue Decoction Extract Against Middle Cerebral Artery Occlusion-Induced Cerebral Ischemia-Reperfusion Injury , 2021, Frontiers in Pharmacology.

[22]  Chao Li,et al.  Pathological changes in neurovascular units: Lessons from cases of vascular dementia , 2021, CNS neuroscience & therapeutics.

[23]  Ming-yu Chen,et al.  Long non-coding RNA nuclear enriched abundant transcript 1 (NEAT1) sponges microRNA-124-3p to up-regulate phosphodiesterase 4B (PDE4B) to accelerate the progression of Parkinson’s disease , 2021, Bioengineered.

[24]  Pravir Kumar,et al.  An integrated approach to unravel a putative crosstalk network in Alzheimer’s disease and Parkinson’s disease , 2020, Neuropeptides.

[25]  X. Chang,et al.  Zishen Huoxue Recipe Protecting Mitochondrial Function of Hypoxic/Reoxygenated Myocardial Cells through mTORC1 Signaling Pathway , 2020, Evidence-based complementary and alternative medicine : eCAM.

[26]  Jin Fan,et al.  Neuron-derived exosomes-transmitted miR-124-3p protect traumatically injured spinal cord by suppressing the activation of neurotoxic microglia and astrocytes , 2020, Journal of Nanobiotechnology.

[27]  W. Liang,et al.  Systematic Understanding of Mechanism of Yi-Qi-Huo-Xue Decoction Against Intracerebral Hemorrhagic Stroke Using a Network Pharmacology Approach , 2020, Medical science monitor : international medical journal of experimental and clinical research.

[28]  W. Gong,et al.  Mincle/Syk signaling promotes intestinal mucosal inflammation through induction of macrophage pyroptosis in Crohn's disease. , 2020, Journal of Crohn's & colitis.

[29]  K. Bettermann,et al.  Current status and future prospects of pathophysiology-based neuroprotective drugs for the treatment of vascular dementia. , 2020, Drug discovery today.

[30]  Yihui Deng,et al.  The Potential Role of MicroRNA-124 in Cerebral Ischemia Injury , 2019, International journal of molecular sciences.

[31]  Jing-jing Xu,et al.  Oxiracetam ameliorates cognitive deficits in vascular dementia rats by regulating the expression of neuronal apoptosis/autophagy-related genes associated with the activation of the Akt/mTOR signaling pathway , 2019, Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.

[32]  Xiao-Lan Fan,et al.  Possible mechanisms of lycopene amelioration of learning and memory impairment in rats with vascular dementia , 2019, Neural regeneration research.

[33]  Shijie Jin,et al.  Exosome reporter mice reveal the involvement of exosomes in mediating neuron to astroglia communication in the CNS , 2019, Nature Communications.

[34]  C. Toro,et al.  Emerging molecular mechanisms of vascular dementia , 2019, Current opinion in hematology.

[35]  Ravi S Muddashetty,et al.  Emerging Role of microRNAs in Dementia. , 2019, Journal of molecular biology.

[36]  Hui Yang,et al.  Structural and functional damage to the hippocampal neurovascular unit in diabetes-related depression , 2019, Neural regeneration research.

[37]  A. Ghorani-Azam,et al.  Herbal medicine as a promising therapeutic approach for the management of vascular dementia: A systematic literature review , 2018, Phytotherapy research : PTR.

[38]  Shu-Qun Liu,et al.  Suppression of MIF-induced neuronal apoptosis may underlie the therapeutic effects of effective components of Fufang Danshen in the treatment of Alzheimer's disease , 2018, Acta Pharmacologica Sinica.

[39]  A. Tolkovsky,et al.  Neuronal Cell Death. , 2018, Physiological reviews.

[40]  Jinwen Yu,et al.  Increased miR‐124‐3p in microglial exosomes following traumatic brain injury inhibits neuronal inflammation and contributes to neurite outgrowth via their transfer into neurons , 2018, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[41]  Miao‐kun Sun,et al.  Potential Therapeutics for Vascular Cognitive Impairment and Dementia , 2017, Current neuropharmacology.

[42]  C. Iadecola The Neurovascular Unit Coming of Age: A Journey through Neurovascular Coupling in Health and Disease , 2017, Neuron.

[43]  Shao-Hua Yang,et al.  Aquaporin 4-Mediated Glutamate-Induced Astrocyte Swelling Is Partially Mediated through Metabotropic Glutamate Receptor 5 Activation , 2017, Front. Cell. Neurosci..

[44]  A. Cardoso,et al.  miRNAs: New Biomarkers and Therapeutic Targets in Dementia. , 2017, Current pharmaceutical design.

[45]  Ding-Feng Su,et al.  miRNA-124 in Immune System and Immune Disorders , 2016, Front. Immunol..

[46]  Shixia Wang,et al.  Identification of QS-21 as an Inflammasome-activating Molecular Component of Saponin Adjuvants* , 2015, The Journal of Biological Chemistry.

[47]  Quan Xia,et al.  Tongqiao Huoxue Decoction ameliorates learning and memory defects in rats with vascular dementia by up-regulating the Ca(2+)-CaMKII-CREB pathway. , 2015, Chinese journal of natural medicines.

[48]  John T O'Brien,et al.  Vascular dementia , 2015, The Lancet.

[49]  M. Chopp,et al.  Models and mechanisms of vascular dementia , 2015, Experimental Neurology.

[50]  Jing Cai,et al.  Bushen Huoxue decoction improves cognitive decline in rats with cerebral hypoperfusion. , 2014, Molecular medicine reports.

[51]  Yuwu Zhao,et al.  Role of Post-Transcriptional Control of Calpain by miR-124-3p in the Development of Alzheimer's Disease. , 2019, Journal of Alzheimer's disease : JAD.