Critical role for conversion of glu-plasminogen to Lys-plasminogen for optimal stimulation of plasminogen activation on cell surfaces.

[1]  M. Ranson,et al.  The topology of plasminogen binding and activation on the surface of human breast cancer cells , 2001, British Journal of Cancer.

[2]  F. Castellino,et al.  Conversion of Glu-Plasminogen to Lys-Plasminogen Is Necessary for Optimal Stimulation of Plasminogen Activation on the Endothelial Cell Surface* , 2001, The Journal of Biological Chemistry.

[3]  L. Miles,et al.  Purification, Cloning, and Characterization of a Profibrinolytic Plasminogen-binding Protein, TIP49a* , 2001, The Journal of Biological Chemistry.

[4]  D. O'Connor,et al.  Processing of chromogranin A by plasmin provides a novel mechanism for regulating catecholamine secretion. , 2000, The Journal of clinical investigation.

[5]  M. Boyle,et al.  The interaction of pathogens with humans. , 2000, Methods.

[6]  Jordi Félez,et al.  Characterization of cell-associated plasminogen activation catalyzed by urokinase-type plasminogen activator, but independent of urokinase receptor (uPAR, CD87). , 1999, Blood.

[7]  V. Sinniger,et al.  Regulation of Tissue Plasminogen Activator Activity by Cells , 1999, The Journal of Biological Chemistry.

[8]  V. Fischetti,et al.  α-Enolase, a Novel Strong Plasmin(ogen) Binding Protein on the Surface of Pathogenic Streptococci* , 1998, The Journal of Biological Chemistry.

[9]  F. Castellino,et al.  Activation of human plasminogen by staphylokinase. Direct evidence that preformed plasmin is necessary for activation to occur. , 1997, Blood.

[10]  P. Ganz,et al.  ENDOTHELIAL CELL SURFACE ACTIN SERVES AS A BINDING SITE FOR PLASMINOGEN, TISSUE PLASMINOGEN ACTIVATOR AND LIPOPROTEIN(a) , 1996, British journal of haematology.

[11]  R. Lottenberg,et al.  The plasmin-binding protein Plr of group A streptococci is identified as glyceraldehyde-3-phosphate dehydrogenase. , 1996, Microbiology.

[12]  A. Horrevoets,et al.  The Activation-resistant Conformation of Recombinant Human Plasminogen Is Stabilized by Basic Residues in the Amino-terminal Hinge Region (*) , 1995, The Journal of Biological Chemistry.

[13]  S. L. Gonias,et al.  A cytokeratin 8-like protein with plasminogen-binding activity is present on the external surfaces of hepatocytes, HepG2 cells and breast carcinoma cell lines. , 1995, Journal of cell science.

[14]  Kanefusa Kato,et al.  Plasminogen Binds Specifically to α‐Enolase on Rat Neuronal Plasma Membrane , 1994 .

[15]  M. Parmely,et al.  Regulation of plasminogen activation by human U937 promonocytic cells. , 1994, The Journal of biological chemistry.

[16]  K. Hajjar,et al.  An endothelial cell receptor for plasminogen/tissue plasminogen activator. I. Identity with annexin II. , 1994, The Journal of biological chemistry.

[17]  R. López-Alemany,et al.  Purification of the plasmin receptor from human carcinoma cells and comparison to α-enolase , 1994 .

[18]  H. Rauvala,et al.  Amphoterin, the 30-kDa protein in a family of HMG1-type polypeptides. Enhanced expression in transformed cells, leading edge localization, and interactions with plasminogen activation. , 1993, The Journal of biological chemistry.

[19]  M. Nesheim,et al.  Lys-plasminogen is a significant intermediate in the activation of Glu-plasminogen during fibrinolysis in vitro. , 1992, The Journal of biological chemistry.

[20]  B. Schwartz,et al.  Single chain urokinase. Augmentation of enzymatic activity upon binding to monocytes. , 1991, The Journal of biological chemistry.

[21]  K. Danø,et al.  Plasminogen activation by receptor-bound urokinase. A kinetic study with both cell-associated and isolated receptor. , 1991, The Journal of biological chemistry.

[22]  K. Danø,et al.  Plasminogen Activation by Receptor-Bound Urokinase , 1991, Seminars in thrombosis and hemostasis.

[23]  S. Pizzo,et al.  Plasmin binding to the plasminogen receptor enhances catalytic efficiency and activates the receptor for subsequent ligand binding. , 1991, Archives of biochemistry and biophysics.

[24]  Jordi Félez,et al.  Role of cell-surface lysines in plasminogen binding to cells: identification of alpha-enolase as a candidate plasminogen receptor. , 1991, Biochemistry.

[25]  T. Rapoport,et al.  A novel pathway for secretory proteins? , 1990, Trends in biochemical sciences.

[26]  E. Plow,et al.  Gangliosides interact directly with plasminogen and urokinase and may mediate binding of these fibrinolytic components to cells. , 1989, Biochemistry.

[27]  M. Scully,et al.  Plasminogen activation initiated by single-chain urokinase-type plasminogen activator. Potentiation by U937 monocytes. , 1989, The Journal of biological chemistry.

[28]  K. Hajjar,et al.  Endothelial cell-mediated conversion of Glu-plasminogen to Lys-plasminogen. Further evidence for assembly of the fibrinolytic system on the endothelial cell surface. , 1988, The Journal of clinical investigation.

[29]  S. Thorsen,et al.  The course and prerequisites of Lys-plasminogen formation during fibrinolysis. , 1988, Biochemistry.

[30]  J. Piatigorsky,et al.  Recruitment of enzymes as lens structural proteins. , 1987, Science.

[31]  J. Loscalzo,et al.  Tissue plasminogen activator promotes platelet disaggregation in plasma. , 1987, The Journal of clinical investigation.

[32]  J. Plescia,et al.  The plasminogen system and cell surfaces: evidence for plasminogen and urokinase receptors on the same cell type , 1986, The Journal of cell biology.

[33]  E. Jaffe,et al.  Binding of plasminogen to cultured human endothelial cells. , 1986, The Journal of biological chemistry.

[34]  D. T. Shiu,et al.  Activation of plasminogen by tissue plasminogen activator on normal and thrombasthenic platelets: effects on surface proteins and platelet aggregation. , 1986, Blood.

[35]  J. White,et al.  Plasminogen interacts with human platelets through two distinct mechanisms. , 1986, The Journal of clinical investigation.

[36]  D. Collen,et al.  A monoclonal antibody specific for Lys-plasminogen. Application to the study of the activation pathways of plasminogen in vivo. , 1985, The Journal of biological chemistry.

[37]  E. Plow,et al.  Binding and activation of plasminogen on the platelet surface. , 1985, The Journal of biological chemistry.

[38]  M. Hoylaerts,et al.  Kinetics of the activation of plasminogen by human tissue plasminogen activator. Role of fibrin. , 1982, The Journal of biological chemistry.

[39]  R. Priore,et al.  The binding of tranexamic acid to native (Glu) and modified (Lys) human plasminogen and its effect on conformation. , 1979, The Journal of biological chemistry.

[40]  G. Markus,et al.  Comparison of some properties of native (Glu) and modified (Lys) human plasminogen. , 1978, The Journal of biological chemistry.

[41]  G. Markus,et al.  Quantitative determination of the binding of epsilon-aminocaproic acid to native plasminogen. , 1978, The Journal of biological chemistry.

[42]  B. Violand,et al.  Mechanism of the urokinase-catalyzed activation of human plasminogen. , 1976, The Journal of biological chemistry.

[43]  T. Astrup,et al.  Reversible and Irreversible Alterations of Human Plasminogen Indicated by Changes in Susceptibility to Plasminogen Activators and in Response to ∈-Aminocaproic Acid , 1974, Thrombosis and Haemostasis.

[44]  T. Astrup,et al.  Substrate Composition and the Effect of ε-Aminocaproic Acid on Tissue Plasminogen Activator and Urokinase-induced Fibrinolysis , 1974, Thrombosis and Haemostasis.

[45]  S. Thorsen,et al.  Rate of activation and electrophoretic mobility of unmodified and partially degraded plasminogen. Effects of 6-aminohexanoic acid and related compounds. , 1974, Scandinavian journal of clinical and laboratory investigation.

[46]  J. Vermylen,et al.  Physico-chemical and proenzyme properties of NH2-terminal glutamic acid and NH2-terminal lysine human plasminogen. Influence of 6-aminohexanoic acid. , 1974, Biochimica et biophysica acta.

[47]  B. Wiman Primary structure of peptides released during activation of human plasminogen by urokinase. , 1973, European journal of biochemistry.

[48]  B. Wiman,et al.  Activation of human plasminogen by an insoluble derivative of urokinase. Structural changes of plasminogen in the course of activation to plasmin and demonstration of a possible intermediate compound. , 1973, European journal of biochemistry.

[49]  Jordi Félez,et al.  Characterization of Cellular Binding Sites and Interactive Regions within Reactants Required for Enhancement of Plasminogen Activation by tPA on the Surface of Leukocytic Cells , 1996, Thrombosis and Haemostasis.

[50]  E. Plow,et al.  The role of an enolase-related molecule in plasminogen binding to cells. , 1995, European journal of biochemistry.

[51]  B. Wiman,et al.  Structural relationship between "glutamic acid" and "lysine" forms of human plasminogen and their interaction with the NH2-terminal activation peptide as studied by affinity chromatography. , 1975, European journal of biochemistry.

[52]  B. Violand,et al.  The effect of ϵ-amino caproic acid on the gross conformation of plasminogen and plasmin , 1975 .