Iris and ciliary body melanocytomas are defined by solitary GNAQ mutation without additional oncogenic alterations.

[1]  L. Dalvin,et al.  Genetic Alterations in Melanocytoma Associated with Oculodermal Melanocytosis: Molecular Characteristics. , 2021, Ophthalmic plastic and reconstructive surgery.

[2]  J. Swensen,et al.  Prognostic Values of G-Protein Mutations in Metastatic Uveal Melanoma , 2021, Cancers.

[3]  B. Bastian,et al.  Functional characterization of uveal melanoma oncogenes , 2020, Oncogene.

[4]  M. Madigan,et al.  Involvement of mutant and wild-type CYSLTR2 in the development and progression of uveal nevi and melanoma , 2020, BMC Cancer.

[5]  K. Covington,et al.  Gene Expression Profiling in Uveal Melanoma: Five-Year Prospective Outcomes and Meta-Analysis , 2020, Ocular Oncology and Pathology.

[6]  Shanshan Liu,et al.  The genetic evolution of metastatic uveal melanoma , 2019, Nature Genetics.

[7]  A. Olshen,et al.  Next-Generation Sequencing of Uveal Melanoma for Detection of Genetic Alterations Predicting Metastasis , 2019, Translational Vision Science & Technology.

[8]  D. Schadendorf,et al.  Integrated Genomic Classification of Melanocytic Tumors of the Central Nervous System Using Mutation Analysis, Copy Number Alterations, and DNA Methylation Profiling , 2018, Clinical Cancer Research.

[9]  A. de Klein,et al.  Genetic Background of Iris Melanomas and Iris Melanocytic Tumors of Uncertain Malignant Potential. , 2018, Ophthalmology.

[10]  M. Madigan,et al.  GNAQ and GNA11 mutations and downstream YAP activation in choroidal nevi , 2017, British Journal of Cancer.

[11]  Joshua M. Stuart,et al.  Integrative Analysis Identifies Four Molecular and Clinical Subsets in Uveal Melanoma. , 2018, Cancer cell.

[12]  D. Schadendorf,et al.  Frequent GNAQ, GNA11, and EIF1AX Mutations in Iris Melanoma. , 2017, Investigative ophthalmology & visual science.

[13]  H. Heimann,et al.  Prognostic biopsy of choroidal melanoma: an optimised surgical and laboratory approach , 2017, British Journal of Ophthalmology.

[14]  Arie Perry,et al.  Targeted next-generation sequencing of pediatric neuro-oncology patients improves diagnosis, identifies pathogenic germline mutations, and directs targeted therapy , 2016, Neuro-oncology.

[15]  B. Taylor,et al.  Recurrent activating mutations of G-protein-coupled receptor CYSLTR2 in uveal melanoma , 2016, Nature Genetics.

[16]  M. Berger,et al.  Investigation of Somatic GNAQ, GNA11, BAP1 and SF3B1 Mutations in Ophthalmic Melanocytomas , 2016, Ocular Oncology and Pathology.

[17]  P. Wesseling,et al.  SF3B1 and EIF1AX mutations occur in primary leptomeningeal melanocytic neoplasms; yet another similarity to uveal melanomas , 2016, Acta neuropathologica communications.

[18]  D. Schadendorf,et al.  Targeted next generation sequencing reveals unique mutation profile of primary melanocytic tumors of the central nervous system , 2016, Journal of Neuro-Oncology.

[19]  N. Hayward,et al.  Deep sequencing of uveal melanoma identifies a recurrent mutation in PLCB4 , 2015, Oncotarget.

[20]  Volker Hovestadt,et al.  Melanotic Tumors of the Nervous System are Characterized by Distinct Mutational, Chromosomal and Epigenomic Profiles , 2015, Brain pathology.

[21]  David T. W. Jones,et al.  Signatures of mutational processes in human cancer , 2013, Nature.

[22]  N. Naus,et al.  Patient survival in uveal melanoma is not affected by oncogenic mutations in GNAQ and GNA11 , 2013, British Journal of Cancer.

[23]  I. Rennie,et al.  Immunohistochemical and molecular pathology of ocular uveal melanocytoma: evidence for somatic GNAQ mutations , 2013, British Journal of Ophthalmology.

[24]  Pratima Kathil,et al.  Characteristics of anterior uveal melanocytomas in 17 cases. , 2011, Ophthalmology.

[25]  J. O'Brien,et al.  Mutations in GNA11 in uveal melanoma. , 2010, The New England journal of medicine.

[26]  R. Scolyer,et al.  Blue Nevi and Related Lesions: A Review Highlighting Atypical and Newly Described Variants, Distinguishing Features and Diagnostic Pitfalls , 2009, Advances in anatomic pathology.

[27]  E. Simpson,et al.  Frequent somatic mutations of GNAQ in uveal melanoma and blue nevi , 2008, Nature.

[28]  C. Shields,et al.  MELANOCYTOMA (HYPERPIGMENTED MAGNOCELLULAR NEVUS) OF THE UVEAL TRACT: The 34th G. Victor Simpson Lecture , 2007, Retina.

[29]  R. L. Font,et al.  Melanocytoma of the ciliary body diagnosed by fine‐needle aspiration biopsy , 2000, Diagnostic cytopathology.

[30]  R. L. Font,et al.  Melanocytoma (magnocellular nevus) of the ciliary body: report of 10 cases and review of the literature. , 2000, Ophthalmology.

[31]  D. Char,et al.  Cytopathologic diagnosis of benign lesions simulating choroidal melanomas. , 1991, American journal of ophthalmology.

[32]  J. Reidy,et al.  Melanocytoma: nomenclature, pathogenesis, natural history and treatment. , 1985, Survey of ophthalmology.

[33]  Ivana K. Kim,et al.  Ocular Melanocytoma , 2009, International ophthalmology clinics.

[34]  C. Shields,et al.  Iris melanocytoma: clinical features and natural course in 47 cases. , 2005, American journal of ophthalmology.

[35]  L. Zimmerman.  MELANOCYTES, MELANOCYTIC NEVI, AND MELANOCYTOMAS. , 1965, Investigative ophthalmology.