Enantioselective Intramolecular C—H Amidation of Sulfamate Esters Catalyzed by Chiral Dirhodium(II) Carboxylates.
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The chiral dirhodium(II) carboxylate-catalyzed enantioselective intramolecular C-H amidation reaction of sulfamate esters via in situ generated iminoiodinanes is described. The use of dirhodium(II) tetrakis[N-tetrafluorophthaloyl-(S)-tert-leucinate], Rh 2 (S-TFPTTL) 4 , as a catalyst and PhI(OAc) 2 as an oxidant provides cyclic sulfamidates in up to 48% ee.
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