Itaconic Acid – An Emerging Building Block

[1]  Matthias G. Steiger,et al.  Characterizing MttA as a mitochondrial cis-aconitic acid transporter by metabolic engineering. , 2016, Metabolic engineering.

[2]  N. Wierckx,et al.  Ustilago maydis produces itaconic acid via the unusual intermediate trans‐aconitate , 2015, Microbial biotechnology.

[3]  H. Alper,et al.  Metabolic engineering of Yarrowia lipolytica for itaconic acid production. , 2015, Metabolic engineering.

[4]  J. Sanders,et al.  Metabolic engineering of the mixed-acid fermentation pathway of Escherichia coli for anaerobic production of glutamate and itaconate , 2015, AMB Express.

[5]  J. Sanders,et al.  Heterologous expression of Mus musculus immunoresponsive gene 1 (irg1) in Escherichia coli results in itaconate production , 2015, Front. Microbiol..

[6]  A. Michelucci,et al.  Itaconic Acid: The Surprising Role of an Industrial Compound as a Mammalian Antimicrobial Metabolite. , 2015, Annual review of nutrition.

[7]  M. Bott,et al.  Metabolic engineering of Corynebacterium glutamicum for the production of itaconate. , 2015, Metabolic engineering.

[8]  C. Kubicek,et al.  A deficiency of manganese ions in the presence of high sugar concentrations is the critical parameter for achieving high yields of itaconic acid by Aspergillus terreus , 2015, Applied Microbiology and Biotechnology.

[9]  Shusuke Okamoto,et al.  Production of itaconic acid in Escherichia coli expressing recombinant α-amylase using starch as substrate. , 2015, Journal of bioscience and bioengineering.

[10]  T. Chin,et al.  Photosynthetic production of itaconic acid in Synechocystis sp. PCC6803. , 2015, Journal of biotechnology.

[11]  M. Sauer,et al.  Organic acids from lignocellulose: Candida lignohabitans as a new microbial cell factory , 2015, Journal of Industrial Microbiology & Biotechnology.

[12]  N. Wierckx,et al.  Prospecting the biodiversity of the fungal family Ustilaginaceae for the production of value-added chemicals , 2014, Fungal Biology and Biotechnology.

[13]  Jan Springer,et al.  Metabolic engineering of itaconate production in Escherichia coli , 2014, Applied Microbiology and Biotechnology.

[14]  Anja Kuenz,et al.  Influence of the pH on the itaconic acid production with Aspergillus terreus , 2014, Applied Microbiology and Biotechnology.

[15]  J. Sanders,et al.  Synthesis of bio-based methacrylic acid by decarboxylation of itaconic acid and citric acid catalyzed by solid transition-metal catalysts. , 2014, ChemSusChem.

[16]  D. Bogdał,et al.  Synthesis of hydrogels by polymerization of itaconic acid–choline chloride deep eutectic solvent , 2014 .

[17]  H. Alper,et al.  Metabolic engineering of Saccharomyces cerevisiae for itaconic acid production , 2014, Applied Microbiology and Biotechnology.

[18]  S. Ménage,et al.  Metabolism: pathogens love the poison. , 2014, Nature chemical biology.

[19]  I. Berg,et al.  Bacterial itaconate degradation promotes pathogenicity. , 2014, Nature chemical biology.

[20]  Anja Kuenz,et al.  Filamentous fungi in microtiter plates—an easy way to optimize itaconic acid production with Aspergillus terreus , 2014, Applied Microbiology and Biotechnology.

[21]  N. Wierckx,et al.  Influence of carbon and nitrogen concentration on itaconic acid production by the smut fungus Ustilago maydis , 2014 .

[22]  J. Cordewener,et al.  Expression of the Aspergillus terreus itaconic acid biosynthesis cluster in Aspergillus niger , 2014, Microbial Cell Factories.

[23]  P. Punt,et al.  A systems biology approach for the identification of target genes for the improvement of itaconic acid production in Aspergillus species , 2013, BMC Research Notes.

[24]  L. D. de Graaff,et al.  Overexpression of a modified 6-phosphofructo-1-kinase results in an increased itaconic acid productivity in Aspergillus niger , 2013, AMB Express.

[25]  Michael Sauer,et al.  Targeting enzymes to the right compartment: metabolic engineering for itaconic acid production by Aspergillus niger. , 2013, Metabolic engineering.

[26]  R. Balling,et al.  Immune-responsive gene 1 protein links metabolism to immunity by catalyzing itaconic acid production , 2013, Proceedings of the National Academy of Sciences.

[27]  P. Punt,et al.  Reduced by-product formation and modified oxygen availability improve itaconic acid production in Aspergillus niger , 2013, Applied Microbiology and Biotechnology.

[28]  Anja Kuenz,et al.  Microbial production of itaconic acid: developing a stable platform for high product concentrations , 2012, Applied Microbiology and Biotechnology.

[29]  Matthias G. Steiger,et al.  Six novel constitutive promoters for metabolic engineering of Aspergillus niger , 2012, Applied Microbiology and Biotechnology.

[30]  Philipp M. Grande,et al.  Biomass pretreatment affects Ustilago maydis in producing itaconic acid , 2012, Microbial Cell Factories.

[31]  Wenyun Lu,et al.  Itaconic acid is a mammalian metabolite induced during macrophage activation. , 2011, Journal of the American Chemical Society.

[32]  M. J. van der Werf,et al.  A clone-based transcriptomics approach for the identification of genes relevant for itaconic acid production in Aspergillus. , 2011, Fungal genetics and biology : FG & B.

[33]  Christoph Wittmann,et al.  Filamentous fungi in good shape: Microparticles for tailor-made fungal morphology and enhanced enzyme production , 2011, Bioengineered bugs.

[34]  Stefan Niemann,et al.  Mycobacterium tuberculosis wears what it eats. , 2010, Cell host & microbe.

[35]  M. Legiša,et al.  Enhancing itaconic acid production by Aspergillus terreus , 2010, Applied Microbiology and Biotechnology.

[36]  Christoph Wittmann,et al.  Morphology engineering of Aspergillus niger for improved enzyme production , 2010, Biotechnology and bioengineering.

[37]  Joseph J. Bozell,et al.  Technology development for the production of biobased products from biorefinery carbohydrates—the US Department of Energy’s “Top 10” revisited , 2010 .

[38]  M. Legiša,et al.  Highly active, citrate inhibition resistant form of Aspergillus niger 6-phosphofructo-1-kinase encoded by a modified pfkA gene. , 2009, Journal of biotechnology.

[39]  E. Park,et al.  Increased riboflavin production from activated bleaching earth by a mutant strain of Ashbya gossypii. , 2009, Journal of bioscience and bioengineering.

[40]  E. Park,et al.  Biotechnological production of itaconic acid and its biosynthesis in Aspergillus terreus , 2009, Applied Microbiology and Biotechnology.

[41]  E. Park,et al.  Cloning and functional characterization of the cis-aconitic acid decarboxylase (CAD) gene from Aspergillus terreus , 2008, Applied Microbiology and Biotechnology.

[42]  L. Dwiarti,et al.  Itaconic acid production using sago starch hydrolysate by Aspergillus terreus TN484-M1. , 2007, Bioresource technology.

[43]  M. Marahiel,et al.  A biosynthetic gene cluster for a secreted cellobiose lipid with antifungal activity from Ustilago maydis , 2007, Molecular microbiology.

[44]  G. Fuchs,et al.  Properties of R-Citramalyl-Coenzyme A Lyase and Its Role in the Autotrophic 3-Hydroxypropionate Cycle of Chloroflexus aurantiacus , 2007, Journal of bacteriology.

[45]  C. Kurtzman,et al.  Production of itaconic acid by Pseudozyma antarctica NRRL Y-7808 under nitrogen-limited growth conditions , 2006 .

[46]  M. Marahiel,et al.  Identification of a Gene Cluster for Biosynthesis of Mannosylerythritol Lipids in the Basidiomycetous Fungus Ustilago maydis , 2006, Applied and Environmental Microbiology.

[47]  Akiko Sakai,et al.  Itaconate reduces visceral fat by inhibiting fructose 2,6-bisphosphate synthesis in rat liver. , 2004, Nutrition.

[48]  Y. Tsai,et al.  Intracellular expression of Vitreoscilla hemoglobin in Aspergillus terreus to alleviate the effect of a short break in aeration during culture , 2004, Biotechnology Letters.

[49]  Christian P. Kubicek,et al.  Aspergillus niger citric acid accumulation: do we understand this well working black box? , 2003, Applied Microbiology and Biotechnology.

[50]  U. Völker,et al.  Oxidation of propionate to pyruvate in Escherichia coli. Involvement of methylcitrate dehydratase and aconitase. , 2002, European journal of biochemistry.

[51]  R. N. Ivanovsky,et al.  Inhibition of acetate and propionate assimilation by itaconate via propionyl-CoA carboxylase in isocitrate lyase-negative purple bacterium Rhodospirillum rubrum. , 2002, FEMS microbiology letters.

[52]  K. Vorlop,et al.  Biotechnological production of itaconic acid , 2001, Applied Microbiology and Biotechnology.

[53]  R. Jain The molecular cloning of genes specifying some enzymes of the 3,5-xylenol degradative pathway , 1996, Applied Microbiology and Biotechnology.

[54]  H. Sahm,et al.  Correlation of isocitrate lyase activity and riboflavin formation in the riboflavin overproducer Ashbya gossypii. , 1996, Microbiology.

[55]  P. Bonnarme,et al.  Itaconate biosynthesis in Aspergillus terreus , 1995, Journal of bacteriology.

[56]  C. Kubicek,et al.  Intracellular location of enzymes involved in citrate production by Aspergillus niger. , 1991, Canadian journal of microbiology.

[57]  C. Kubicek,et al.  The subcellular organization of itaconate biosynthesis in Aspergillus terreus , 1991 .

[58]  N. Winskillm Tricarboxylic Acid Cycle Activity in Relation to Itaconic Acid Biosynthesis by Aspergillus terreus , 1983 .

[59]  J. Adler,et al.  The metabolism of itaconic acid by liver mitochondria. , 1957, The Journal of biological chemistry.

[60]  R. Bentley,et al.  Biosynthesis of itaconic acid in Aspergillus terreus. I. Tracer studies with C14-labeled substrates. , 1957, The Journal of biological chemistry.

[61]  Albert N. Booth,et al.  The inhibitory effects of itaconic acid in vitro and in vivo. , 1952, The Journal of biological chemistry.

[62]  M. Friedkin,et al.  Itatartaric acid, a metabolic product of an ultravioletinduced mutant of Aspergillus terreus. , 1945, The Journal of biological chemistry.

[63]  C. T. Calam,et al.  Studies in the biochemistry of micro-organisms: Itaconic acid, a metabolic product of a strain of Aspergillus terreus Thom. , 1939 .

[64]  Shusuke Okamoto,et al.  Production of itaconic acid using metabolically engineered Escherichia coli. , 2014, The Journal of general and applied microbiology.

[65]  J. Adler,et al.  The pathway of itaconate metabolism by liver mitochondria. , 1961, The Journal of biological chemistry.

[66]  廣野 木下 麹菌族ノ一新種イタコン酸菌 (Aspergillus itaconicus nov. spec.) ニ就テ (豫報) , 1931 .

[67]  S. Baup Ueber eine neue Pyrogen‐Citronensäure, und über Benennung der Pyrogen‐Säuren überhaupt , 1836 .