Ground walk training improves functional exercise capacity more than cycle training in people with chronic obstructive pulmonary disease (COPD): a randomised trial.

QUESTIONS Does an eight-week program of walk training improve endurance walking capacity in people with COPD compared to cycle training? Does walk training improve peak walking capacity, cycle capacity, and quality of life compared to cycle training? Is the endurance shuttle walk test (ESWT) responsive to change in walking capacity elicited by exercise training? DESIGN Randomised trial with concealed allocation, assessor blinding, and intention-to-treat analysis. PARTICIPANTS 36 people with stable COPD recruited with four dropouts. INTERVENTION Participants were randomised into either a walk or cycle training group. Both groups trained indoors for 30 to 45 minutes per session, three times weekly over eight weeks at Concord Hospital. Training intensities were based on baseline peak exercise tests and progressed as able. OUTCOME MEASURES The primary outcome was endurance walking capacity measured by the ESWT. Secondary outcomes included peak walking capacity, peak and endurance cycle capacity, and health-related quality of life. Measures were taken at baseline (Week 0) and following training (Week 8). RESULTS The walk training group increased their endurance walking time by 279 seconds (95% CI 70 to 483) more than the cycle training group. No significant differences between the groups were found for any other outcome. CONCLUSION Ground walk training increased endurance walking capacity more than cycle training and was similar to cycle training in improving peak walking capacity, peak and endurance cycle capacity and quality of life. This study provides evidence for ground walking as a mode of exercise training in pulmonary rehabilitation programs.

[1]  A. Ries,et al.  Effects of Pulmonary Rehabilitation on Physiologic and Psychosocial Outcomes in Patients with Chronic Obstructive Pulmonary Disease , 1995, Annals of Internal Medicine.

[2]  A. Hardman,et al.  The endurance shuttle walk: a new field test for the assessment of endurance capacity in chronic obstructive pulmonary disease. , 1999, Thorax.

[3]  D. House,et al.  Chronic respiratory disease: in military inductees and parents of schoolchildren. , 1973, Archives of environmental health.

[4]  J. Hankinson,et al.  Standardisation of spirometry , 2005, European Respiratory Journal.

[5]  J. Hankinson,et al.  Standardisation of the single-breath determination of carbon monoxide uptake in the lung , 2005, European Respiratory Journal.

[6]  Sally J. Singh,et al.  How long should outpatient pulmonary rehabilitation be? A randomised controlled trial of 4 weeks versus 7 weeks , 2006, Thorax.

[7]  J E Cotes,et al.  Lung volumes and forced ventilatory flows. Report Working Party Standardization of Lung Function Tests, European Community for Steel and Coal. Official Statement of the European Respiratory Society. , 1993, The European respiratory journal. Supplement.

[8]  R. Casaburi,et al.  Comparison of effects of supervised versus self-monitored training programmes in patients with chronic obstructive pulmonary disease. , 2000, The European respiratory journal.

[9]  S. Brophy,et al.  Interventions for latent autoimmune diabetes (LADA) in adults. , 2011, The Cochrane database of systematic reviews.

[10]  G. Guyatt,et al.  Measurement of health status. Ascertaining the minimal clinically important difference. , 1989, Controlled clinical trials.

[11]  R. Klocke,et al.  THE AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE , 1994 .

[12]  G. Viegi,et al.  Standardisation of the measurement of lung volumes , 2005, European Respiratory Journal.

[13]  C. D. Mathers,et al.  Chronic obstructive pulmonary disease: current burden and future projections , 2006, European Respiratory Journal.

[14]  G. Guyatt,et al.  A measure of quality of life for clinical trials in chronic lung disease. , 1987, Thorax.

[15]  F. Maltais,et al.  Skeletal muscle adaptation to endurance training in patients with chronic obstructive pulmonary disease. , 1996, American journal of respiratory and critical care medicine.

[16]  F. Maltais,et al.  Intensity of training and physiologic adaptation in patients with chronic obstructive pulmonary disease. , 1997, American journal of respiratory and critical care medicine.

[17]  K. R. Chapman,et al.  Epidemiology and costs of chronic obstructive pulmonary disease , 2006, European Respiratory Journal.

[18]  R. Casaburi,et al.  Physiologic benefits of exercise training in rehabilitation of patients with severe chronic obstructive pulmonary disease. , 1997, American journal of respiratory and critical care medicine.

[19]  S. Hung,et al.  Efficacy of a cell phone-based exercise programme for COPD , 2008, European Respiratory Journal.

[20]  G. Guyatt,et al.  Randomised controlled trial of respiratory rehabilitation , 1994, The Lancet.

[21]  J. Maurer Effects of Home-Based Pulmonary Rehabilitation in Patients with Chronic Obstructive Pulmonary Disease: A Randomized Trial , 2010 .

[22]  J. Zieliński,et al.  Prevalence, severity and underdiagnosis of COPD in the primary care setting , 2008, Thorax.

[23]  M. S. Singh,et al.  Development of a shuttle walking test of disability in patients with chronic airways obstruction. , 1992, Thorax.

[24]  G. Borg Psychophysical bases of perceived exertion. , 1982, Medicine and science in sports and exercise.

[25]  Richard Casaburi,et al.  Pulmonary Rehabilitation: Joint ACCP/AACVPR Evidence-Based Clinical Practice Guidelines. , 2007, Chest.

[26]  P. Lange,et al.  Rehabilitation in COPD: the long-term effect of a supervised 7-week program succeeded by a self-monitored walking program , 2008, Chronic respiratory disease.

[27]  J E Cotes,et al.  Lung volumes and forced ventilatory flows , 1993, European Respiratory Journal.

[28]  R. Benzo,et al.  Optimal protocol selection for cardiopulmonary exercise testing in severe COPD. , 2007, Chest.

[29]  Brian Hutton,et al.  Effects of Home-Based Pulmonary Rehabilitation in Patients with Chronic Obstructive Pulmonary Disease , 2008, Annals of Internal Medicine.

[30]  M. Abdalla,et al.  SF 36 health survey questionnaire: II. Responsiveness to changes in health status in four common clinical conditions. , 1994, Quality in health care : QHC.

[31]  M. Decramer,et al.  Six minute walking distance in healthy elderly subjects. , 1999, The European respiratory journal.

[32]  J E Cotes,et al.  [Lung volumes and forced ventilatory flows. Work Group on Standardization of Respiratory Function Tests. European Community for Coal and Steel. Official position of the European Respiratory Society]. , 1994, Revue des maladies respiratoires.

[33]  R. Casaburi Factors Determining Constant Work Rate Exercise Tolerance in COPD and their Role in Dictating the Minimal Clinically Important Difference in Response to Interventions , 2005, COPD.

[34]  T. Rubio,et al.  Results of a home-based training program for patients with COPD. , 2000, Chest.

[35]  J. Alison,et al.  Relationship between field walking tests and incremental cycle ergometry in COPD , 2008, Respirology.

[36]  H. Folgering,et al.  Pulmonary rehabilitation in chronic obstructive pulmonary disease. , 1998, The European respiratory journal.

[37]  R. Casaburi,et al.  Reductions in exercise lactic acidosis and ventilation as a result of exercise training in patients with obstructive lung disease. , 1991, The American review of respiratory disease.