Clinically identified maternal depression before, during, and after pregnancies ending in live births.

OBJECTIVE This study estimated the prevalence of diagnosed depression and treatment among women before, during, and after pregnancies ending in live births. METHOD A previously validated algorithm identified health plan members with at least one pregnancy between Jan. 1, 1998, and Dec. 31, 2001. Women with a pregnancy ending in one or more live births and continuously enrolled from 39 weeks before pregnancy through 39 weeks after pregnancy were eligible. Maternal depression was identified from the medical records. Depression treatment included antidepressant medication and/or mental health visits. The authors examined the prevalence of depression and treatments received. RESULTS Among 4,398 continuously enrolled women with eligible pregnancies ending in live births, 678 (15.4%) had depression identified during at least one pregnancy phase; 8.7%, 6.9%, and 10.4% had depression identified before, during, and/or after pregnancy, respectively. Among women with identified depression during the 39 weeks before pregnancy, 56.4% also had a depression diagnosis during pregnancy. Of women identified with depression during the 39 weeks following pregnancy, 54.2% had depression diagnoses either during or preceding pregnancy. Most women diagnosed with depression received antidepressant medications and/or had at least one mental health visit. Having at least one mental health visit did not vary before, during, or after pregnancy; however, antidepressant use was lower during pregnancy than before or after pregnancy. CONCLUSIONS Approximately one in seven women was identified with and treated for depression during 39 weeks before through 39 weeks after pregnancy, and more than half of these women had recurring indicators for depression.

[1]  C. Berg,et al.  Development of an algorithm to identify pregnancy episodes in an integrated health care delivery system. , 2007, Health services research.

[2]  Simon Gilbody,et al.  Should we screen for depression? , 2006, BMJ : British Medical Journal.

[3]  S. Hernández-Díaz,et al.  Selective Serotonin-Reuptake Inhibitors and Risk of Persistent Pulmonary Hypertension of the Newborn , 2006, The New England journal of medicine.

[4]  T. Einarson,et al.  Newer antidepressants in pregnancy and rates of major malformations: a meta‐analysis of prospective comparative studies , 2005, Pharmacoepidemiology and drug safety.

[5]  K. Lohr,et al.  Perinatal Depression: A Systematic Review of Prevalence and Incidence , 2005, Obstetrics and gynecology.

[6]  K. Lohr,et al.  Perinatal depression: prevalence, screening accuracy, and screening outcomes. , 2005, Evidence report/technology assessment.

[7]  A. Rush,et al.  Onset and persistence of postpartum depression in an inner-city maternal health clinic system. , 2001, The American journal of psychiatry.

[8]  B. Yawn,et al.  Routine screening for postpartum depression. , 2001, The Journal of family practice.

[9]  M. Palta,et al.  Predictors, prodromes and incidence of postpartum depression , 2001, Journal of psychosomatic obstetrics and gynaecology.

[10]  Lisa V. Rubenstein,et al.  Who is at risk of nondetection of mental health problems in primary care? , 2000, Journal of General Internal Medicine.

[11]  A. Lane,et al.  Postnatal depression and elation among mothers and their partners: Prevalence and predictors , 1997, British Journal of Psychiatry.

[12]  M. O’Hara,et al.  Rates and risk of postpartum depression—a meta-analysis , 1996 .

[13]  Cheryl Tatano Beck The Effects of Postpartum Depression on Maternal‐Infant Interaction: A Meta‐Analysis , 1995, Nursing research.

[14]  Michael R. Hulsizer,et al.  Depression prevalence and incidence among inner-city pregnant and postpartum women. , 1995, Journal of consulting and clinical psychology.

[15]  L. Holland,et al.  Postnatal depression: a Christchurch study. , 1995, The New Zealand medical journal.

[16]  T. Field Infants of depressed mothers , 1992, Development and Psychopathology.

[17]  J. Cohn,et al.  Prevalence and correlates of postpartum depression in first-time mothers. , 1991, Journal of abnormal psychology.

[18]  D. Regier,et al.  Comparing age at onset of major depression and other psychiatric disorders by birth cohorts in five US community populations. , 1991, Archives of general psychiatry.

[19]  M. O’Hara,et al.  Prospective study of postpartum depression: 4 1/2-year follow-up of women and children. , 1991, Journal of abnormal psychology.

[20]  I. Gotlib,et al.  Prevalence rates and demographic characteristics associated with depression in pregnancy and the postpartum. , 1989, Journal of consulting and clinical psychology.

[21]  J. Ballenger Relapse of Major Depression During Pregnancy in Women Who Maintain or Discontinue Antidepressant Treatment , 2007 .

[22]  K. Kemper,et al.  Medical management of depression. , 2006, The New England journal of medicine.