Free radicals contribute to the reduction in peripheral vascular responses and the maintenance of thermal hyperalgesia in rats with chronic constriction injury

[1]  J. Garthwaite,et al.  The nitric oxide-cyclic GMP pathway is required for nociceptive signalling at specific loci within the somatosensory pathway , 1996, Neuroscience.

[2]  S. Raja,et al.  Neuropathic pain in rats is associated with altered nitric oxide synthase activity in neural tissue , 1996, Journal of the Neurological Sciences.

[3]  P. Chan,et al.  Role of oxidants in ischemic brain damage. , 1996, Stroke.

[4]  T. Dawson,et al.  Nitric oxide neurotoxicity , 1996, Journal of Chemical Neuroanatomy.

[5]  M. Tal.  A novel antioxidant alleviates heat hyperalgesia in rats with an experimental painful peripheral neuropathy. , 1996, Neuroreport.

[6]  R. Dubner,et al.  Application of nitric oxide synthase inhibitor, N ω-nitro-l-arginine methyl ester, on injured nerve attenuates neuropathy-induced thermal hyperalgesia in rats , 1996, Neuroscience Letters.

[7]  E. Hall,et al.  Protective effects of tirilazad mesylate in a cellular model of peroxynitrite toxicity. , 1996, Research communications in molecular pathology and pharmacology.

[8]  W. Alves,et al.  Randomized, double-blind, vehicle-controlled trial of tirilazad mesylate in patients with aneurysmal subarachnoid hemorrhage: a cooperative study in Europe, Australia, and New Zealand. , 1996, Journal of neurosurgery.

[9]  E. Hall.  Inhibition of lipid peroxidation in central nervous system trauma and ischemia , 1995, Journal of the Neurological Sciences.

[10]  R. Helme,et al.  Role of nitric oxide in the actions of substance P and other mediators of inflammation in rat skin microvasculature. , 1995, European journal of pharmacology.

[11]  J. D. Richardson,et al.  Glutamate participates in the peripheral modulation of thermal hyperalgesia in rats. , 1995, European journal of pharmacology.

[12]  S. Myers,et al.  Oxygen free radicals regulate splanchnic nitric oxide synthesis and blood flow. , 1995, Cardiovascular surgery.

[13]  J. K. Muir,et al.  Superoxide dismutase improves posttraumatic cortical blood flow in rats. , 1995, Journal of neurotrauma.

[14]  P. Manson,et al.  Free Radical Damage in Acute Nerve Compression , 1995, Annals of plastic surgery.

[15]  T. Mashimo,et al.  Intracerebroventricular administration of a nitric oxide-releasing compound, NOC-18, produces thermal hyperalgesia in rats , 1995, Neuroscience Letters.

[16]  L. Watkins,et al.  Illness-induced hyperalgesia is mediated by a spinal NMDA-nitric oxide cascade , 1994, Brain Research.

[17]  S. Maier,et al.  Illness-induced hyperalgesia is mediated by spinal neuropeptides and excitatory amino acids , 1994, Brain Research.

[18]  T. Feasby,et al.  Lewis rat EAN is suppressed by the 21–aminosteroid tirilazad mesylate (U–74006F) , 1994, Neuropathology and applied neurobiology.

[19]  T. Asano,et al.  Effects of new 21-aminosteroid tirilazad mesylate (U74006F) on chronic cerebral vasospasm in a "two-hemorrhage" model of beagle dogs. , 1994, Neurosurgery.

[20]  E. Hall,et al.  The use of salicylate hydroxylation to detect hydroxyl radical generation in ischemic and traumatic brain injury. Reversal by tirilazad mesylate (U-74006F). , 1993, Molecular and chemical neuropathology.

[21]  T. Schwartz,et al.  Chimeric NK1 (substance P)/NK3 (neurokinin B) receptors. Identification of domains determining the binding specificity of tachykinin agonists. , 1993, The Journal of biological chemistry.

[22]  R. Helme,et al.  Management of chronic pain , 1993, The Medical journal of Australia.

[23]  R. Helme,et al.  Skin vascular reactivity to the neuropeptide substance P in rats with peripheral mononeuropathy , 1993, Pain.

[24]  Jin Mo Chung,et al.  An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat , 1992, PAIN.

[25]  R. Helme,et al.  Nitric oxide and sensory nerves are involved in the vasodilator response to acetylcholine but not calcitonin gene‐related peptide in rat skin micro vasculature , 1992 .

[26]  F. Laurindo,et al.  Evidence for Superoxide Radical–Dependent Coronary Vasospasm After Angioplasty in Intact Dogs , 1991, Circulation.

[27]  C. G. Mellow,et al.  Secondary ischaemia in rabbit skin flaps: the roles played by thromboxane and free radicals. , 1991, Clinical science.

[28]  Ronald Dubner,et al.  A novel behavioral model of neuropathic pain disorders produced in rats by partial sciatic nerve injury , 1990, Pain.

[29]  R. Helme,et al.  Serotonin modulates substance P-induced plasma extravasation and vasodilatation in rat skin by an action through capsaicin-sensitive primary afferent nerves , 1990, Brain Research.

[30]  M. Mayer,et al.  Excitatory amino acid receptors, second messengers and regulation of intracellular Ca2+ in mammalian neurons. , 1990, Trends in pharmacological sciences.

[31]  N. Attal,et al.  Further evidence for ‘pain-related’ behaviours in a model of unilateral peripheral mononeuropathy , 1990, Pain.

[32]  B. Freeman,et al.  Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[33]  R. Helme,et al.  Sequence of events in substance P-mediated plasma extravasation in rat skin , 1989, Brain Research.

[34]  Y. Nishizuka.  The Family of Protein Kinase C for Signal Transduction , 1989 .

[35]  R. Helme,et al.  Tachykinin-induced vasodilatation in rat skin measured with a laser-Doppler flowmeter: evidence for receptor-mediated effects , 1989, Regulatory Peptides.

[36]  G. Gross,et al.  Oxygen free radicals abolish endothelium-dependent relaxation in diabetic rat aorta. , 1988, The American journal of physiology.

[37]  Gary J. Bennett,et al.  A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man , 1988, Pain.

[38]  A. Dickenson,et al.  Evidence for a role of the NMDA receptor in the frequency dependent potentiation of deep rat dorsal horn nociceptive neurones following c fibre stimulation. , 1987, Neuropharmacology.

[39]  W. Swartz,et al.  The Etiologic Role of Free Radicals in Hematoma-Induced Flap Necrosis , 1986, Plastic and reconstructive surgery.

[40]  S. Moncada,et al.  Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor , 1986, Nature.

[41]  J. McCord,et al.  Oxygen-derived free radicals in postischemic tissue injury. , 1985, The New England journal of medicine.

[42]  J. McCord,et al.  Free Radicals as Mediators of Tissue Injury , 1980 .