Design, synthesis, and evaluation of novel 3-amino-4-hydrazine-cyclobut-3-ene-1,2-diones as potent and selective CXCR2 chemokine receptor antagonists.
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Yongxin Han | S. Kargman | R. Lobell | R. Friesen | Yili Ding | D. Stout | Leanne Bédard | M. Chan | Hao Wu | N. Sawyer | Shilan Liu | F. Gervais | Martin Hénault | Ge Li | A. Wong | Jingchao Dong | Hongmei Wang | Shuhui Chen | Yin-hong Liu
[1] Akbar Ali,et al. Design and synthesis of HIV-1 protease inhibitors incorporating oxazolidinones as P2/P2' ligands in pseudosymmetric dipeptide isosteres. , 2007, Journal of medicinal chemistry.
[2] Younong Yu,et al. A new synthesis of 3,4-disubstituted 1,2,5-thiadiazoles , 2007 .
[3] Wei-Chang Fu,et al. 3-Arylamino-2H-1,2,4-benzothiadiazin-5-ol 1,1-dioxides as novel and selective CXCR2 antagonists. , 2007, Bioorganic & medicinal chemistry letters.
[4] M. Dwyer,et al. C(4)-alkyl substituted furanyl cyclobutenediones as potent, orally bioavailable CXCR2 and CXCR1 receptor antagonists. , 2007, Bioorganic & medicinal chemistry letters.
[5] K. Ward,et al. Comparison of N,N'-diarylsquaramides and N,N'-diarylureas as antagonists of the CXCR2 chemokine receptor. , 2007, Bioorganic & medicinal chemistry letters.
[6] M. Dwyer,et al. Discovery of 2-hydroxy-N,N-dimethyl-3-{2-[[(R)-1-(5- methylfuran-2-yl)propyl]amino]-3,4-dioxocyclobut-1-enylamino}benzamide (SCH 527123): a potent, orally bioavailable CXCR2/CXCR1 receptor antagonist. , 2006, Journal of medicinal chemistry.
[7] J. D. Elliott,et al. N,N'-Diarylcyanoguanidines as antagonists of the CXCR2 and CXCR1 chemokine receptors. , 2006, Bioorganic & medicinal chemistry letters.
[8] M. Dwyer,et al. Synthesis and structure-activity relationships of 3,4-diaminocyclobut-3-ene-1,2-dione CXCR2 antagonists. , 2006, Bioorganic & medicinal chemistry letters.
[9] J. Busch-Petersen. Small molecule antagonists of the CXCR2 and CXCR1 chemokine receptors as therapeutic agents for the treatment of inflammatory diseases. , 2006, Current topics in medicinal chemistry.
[10] John Unitt,et al. Hit-to-Lead studies: the discovery of potent, orally bioavailable thiazolopyrimidine CXCR2 receptor antagonists. , 2006, Bioorganic & medicinal chemistry letters.
[11] H. Sajiki,et al. Reductive and catalytic monoalkylation of primary amines using nitriles as an alkylating reagent. , 2004, Organic letters.
[12] E. Lescop,et al. Novel azapeptide inhibitors of hepatitis C virus serine protease. , 2004, Journal of medicinal chemistry.
[13] J. D. Elliott,et al. Evaluation of potent and selective small-molecule antagonists for the CXCR2 chemokine receptor. , 2004, Journal of medicinal chemistry.
[14] Marlene Wolf,et al. Chemokines: multiple levels of leukocyte migration control. , 2004, Trends in immunology.
[15] N. Iranpoor,et al. Selective N-nitrosation of amines, N-alkylamides and N-alkylureas by N2O4 supported on cross-linked polyvinylpyrrolidone (PVP-N2O4) , 2003 .
[16] Rolf Hilgenfeld,et al. Coronavirus Main Proteinase (3CLpro) Structure: Basis for Design of Anti-SARS Drugs , 2003, Science.
[17] D. Norbeck,et al. Inhibition of 3C protease from human rhinovirus strain 1B by peptidyl bromomethylketonehydrazides. , 1999, Archives of biochemistry and biophysics.
[18] J. Mestan,et al. New aza-dipeptide analogues as potent and orally absorbed HIV-1 protease inhibitors: candidates for clinical development. , 1998, Journal of medicinal chemistry.
[19] D. C. Iffland,et al. Oxidation of N,N-Disubstituted Ketohydrazones by Lead Tetraacetate. Carbon—Nitrogen Bond Cleavage1 , 1963 .