The anticonvulsive Phenhydan® suppresses extrinsic cell death
暂无分享,去创建一个
U. Kunzendorf | J. Bräsen | P. Meier | C. Günther | J. Schmitz | James M. Murphy | A. Jacobsen | Caroline Moerke | J. Fritsch | S. Krautwald | Christin Dewitz | I. Jaco | J. Gautheron | Tammo Müller
[1] Carlina Duan. Programmed , 2020, Pleiades: Literature in Context.
[2] U. Kunzendorf,et al. The anticonvulsive Phenhydan® suppresses extrinsic cell death , 2018, Cell Death & Differentiation.
[3] E. Bieberich. Sphingolipids and lipid rafts: Novel concepts and methods of analysis. , 2018, Chemistry and physics of lipids.
[4] Susan S. Taylor,et al. Kinase domain dimerization drives RIPK3-dependent necroptosis , 2018, Science Signaling.
[5] Brian J. Smith,et al. Conformational switching of the pseudokinase domain promotes human MLKL tetramerization and cell death by necroptosis , 2018, Nature Communications.
[6] Junying Yuan,et al. Small molecule probes for cellular death machines. , 2017, Current opinion in chemical biology.
[7] R. Kontermann,et al. Novel strategies to mimic transmembrane tumor necrosis factor-dependent activation of tumor necrosis factor receptor 2 , 2017, Scientific Reports.
[8] B. Stockwell,et al. Necroptosis and ferroptosis are alternative cell death pathways that operate in acute kidney failure , 2017, Cellular and Molecular Life Sciences.
[9] Michelle C. Schaeffer,et al. Discovery of a First-in-Class Receptor Interacting Protein 1 (RIP1) Kinase Specific Clinical Candidate (GSK2982772) for the Treatment of Inflammatory Diseases. , 2017, Journal of medicinal chemistry.
[10] Chuan-Qi Zhong,et al. RIP1 autophosphorylation is promoted by mitochondrial ROS and is essential for RIP3 recruitment into necrosome , 2017, Nature Communications.
[11] P. Vandenabeele,et al. The pseudokinase MLKL mediates programmed hepatocellular necrosis independently of RIPK3 during hepatitis. , 2016, The Journal of clinical investigation.
[12] Zhirong Shen,et al. Biomarkers for the detection of necroptosis , 2016, Cellular and Molecular Life Sciences.
[13] D. Vaux,et al. Evolutionary divergence of the necroptosis effector MLKL , 2016, Cell Death and Differentiation.
[14] James M. Murphy. Faculty Opinions recommendation of Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha. , 2015 .
[15] W. Alexander,et al. Necroptosis signalling is tuned by phosphorylation of MLKL residues outside the pseudokinase domain activation loop. , 2015, The Biochemical journal.
[16] G. Superti-Furga,et al. A cellular screen identifies ponatinib and pazopanib as inhibitors of necroptosis , 2015, Cell Death and Disease.
[17] F. Chan,et al. Programmed necrosis in the cross talk of cell death and inflammation. , 2015, Annual review of immunology.
[18] I. Parmryd,et al. Cholesterol depletion using methyl-β-cyclodextrin. , 2015, Methods in molecular biology.
[19] Kenta Moriwaki,et al. RIP3 induces apoptosis independent of pronecrotic kinase activity. , 2014, Molecular cell.
[20] S. Cullen,et al. RIPK1 can function as an inhibitor rather than an initiator of RIPK3‐dependent necroptosis , 2014, The FEBS journal.
[21] Qin Chen,et al. Direct activation of RIP3/MLKL-dependent necrosis by herpes simplex virus 1 (HSV-1) protein ICP6 triggers host antiviral defense , 2014, Proceedings of the National Academy of Sciences.
[22] M. Bertrand,et al. MLKL compromises plasma membrane integrity by binding to phosphatidylinositol phosphates. , 2014, Cell reports.
[23] Xiaodong Wang,et al. Mixed lineage kinase domain-like protein MLKL causes necrotic membrane disruption upon phosphorylation by RIP3. , 2014, Molecular cell.
[24] L. Komuves,et al. Activity of Protein Kinase RIPK3 Determines Whether Cells Die by Necroptosis or Apoptosis , 2014, Science.
[25] S. Sottini,et al. The β-Subunit of Cholera Toxin has a High Affinity for Ganglioside GM1 Embedded into Solid Supported Lipid Membranes with a Lipid Raft-Like Composition , 2014, Lipids.
[26] Toru Okamoto,et al. The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism. , 2013, Immunity.
[27] J. Bertin,et al. Toll-like Receptor 3-mediated Necrosis via TRIF, RIP3, and MLKL* , 2013, The Journal of Biological Chemistry.
[28] D. Green,et al. Two independent pathways of regulated necrosis mediate ischemia–reperfusion injury , 2013, Proceedings of the National Academy of Sciences.
[29] W. Schneider-Brachert,et al. Membrane Trafficking of Death Receptors: Implications on Signalling , 2013, International journal of molecular sciences.
[30] Chung Hyeok Kim,et al. Biomedical Importance of Indoles , 2013, Molecules.
[31] P. Vandenabeele,et al. Necrostatin-1 analogues: critical issues on the specificity, activity and in vivo use in experimental disease models , 2012, Cell Death and Disease.
[32] R. Dudani,et al. Type I interferon induces necroptosis in macrophages during infection with Salmonella enterica serovar Typhimurium , 2012, Nature Immunology.
[33] Xiaodong Wang,et al. Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase , 2012, Cell.
[34] Yuqiong Liang,et al. Toll-like receptors activate programmed necrosis in macrophages through a receptor-interacting kinase-3–mediated pathway , 2011, Proceedings of the National Academy of Sciences.
[35] H. Steller,et al. Programmed Cell Death in Animal Development and Disease , 2011, Cell.
[36] J. Bonventre,et al. Cellular pathophysiology of ischemic acute kidney injury. , 2011, The Journal of clinical investigation.
[37] D. Kabelitz,et al. Caspase‐8 and caspase‐7 sequentially mediate proteolytic activation of acid sphingomyelinase in TNF‐R1 receptosomes , 2011, The EMBO journal.
[38] Helgi I. Ingólfsson,et al. Gramicidin-based fluorescence assay; for determining small molecules potential for modifying lipid bilayer properties. , 2010, Journal of visualized experiments : JoVE.
[39] S. Johannessen,et al. Antiepileptic Drug Interactions - Principles and Clinical Implications , 2010, Current neuropharmacology.
[40] B. Beutler,et al. Intracellular toll-like receptors. , 2010, Immunity.
[41] Na Zhang,et al. RIP3, an Energy Metabolism Regulator That Switches TNF-Induced Cell Death from Apoptosis to Necrosis , 2009, Science.
[42] F. Chan,et al. Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation , 2009, Cell.
[43] Tao Wang,et al. Receptor Interacting Protein Kinase-3 Determines Cellular Necrotic Response to TNF-α , 2009, Cell.
[44] M. Toyota,et al. Identification of Flotillin-2, a Major Protein on Lipid Rafts, as a Novel Target of p53 Family Members , 2008, Molecular Cancer Research.
[45] F. Khuri,et al. Lipid rafts and nonrafts mediate tumor necrosis factor related apoptosis-inducing ligand induced apoptotic and nonapoptotic signals in non small cell lung carcinoma cells. , 2007, Cancer research.
[46] G. Nixon,et al. Spatial Compartmentalization of Tumor Necrosis Factor (TNF) Receptor 1-dependent Signaling Pathways in Human Airway Smooth Muscle Cells , 2006, Journal of Biological Chemistry.
[47] Alexei Degterev,et al. Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury , 2005, Nature chemical biology.
[48] T. Griffith,et al. Depsipeptide (FR901228) enhances the cytotoxic activity of TRAIL by redistributing TRAIL receptor to membrane lipid rafts. , 2005, Molecular therapy : the journal of the American Society of Gene Therapy.
[49] W. D. Dietrich,et al. Tumor Necrosis Factor Receptor 1 and Its Signaling Intermediates Are Recruited to Lipid Rafts in the Traumatized Brain , 2004, The Journal of Neuroscience.
[50] L. Chamberlain. Detergents as tools for the purification and classification of lipid rafts , 2004, FEBS letters.
[51] Hai-Tao He,et al. An essential role for membrane rafts in the initiation of Fas/CD95‐triggered cell death in mouse thymocytes , 2002, EMBO reports.
[52] J. Medin,et al. A neutral sphingomyelinase resides in sphingolipid-enriched microdomains and is inhibited by the caveolin-scaffolding domain: potential implications in tumour necrosis factor signalling. , 2001, The Biochemical journal.
[53] F. Pinguet,et al. Antiproliferative effect of methyl-beta-cyclodextrin in vitro and in human tumour xenografted athymic nude mice. , 1998, British Journal of Cancer.
[54] A. Wendel,et al. A T cell-dependent experimental liver injury in mice inducible by concanavalin A. , 1992, The Journal of clinical investigation.