Post-translational modifications by SIRT3 de-2-hydroxyisobutyrylase activity regulate glycolysis and enable nephrogenesis
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G. Remuzzi | A. Benigni | B. Imberti | C. Xinaris | M. Morigi | S. Conti | C. Zoja | Luca Perico | S. Tomasoni | F. Sangalli | C. Zanchi | A. Pezzotta | D. Corna | Valerio Brizi | P. Trionfini | Sara Buttò | Cristina Zanchi
[1] G. Azhar,et al. Alternative Splicing Increases Sirtuin Gene Family Diversity and Modulates Their Subcellular Localization and Function , 2021, International journal of molecular sciences.
[2] C. Scafoglio,et al. Metabolic Regulation of Epigenetic Modifications and Cell Differentiation in Cancer , 2020, Cancers.
[3] J. Locasale,et al. The evolving metabolic landscape of chromatin biology and epigenetics , 2020, Nature Reviews Genetics.
[4] Shai-hong Zhu,et al. Histone Acetyltransferase p300 Inhibitor Improves Coronary Flow Reserve in SIRT3 (Sirtuin 3) Knockout Mice , 2020, Journal of the American Heart Association.
[5] Z. Saifudeen,et al. The polycomb proteins EZH1 and EZH2 co-regulate chromatin accessibility and nephron progenitor cell lifespan in mice , 2020, The Journal of Biological Chemistry.
[6] G. Remuzzi,et al. Manipulating Sirtuin 3 pathway ameliorates renal damage in experimental diabetes , 2020, Scientific Reports.
[7] P. Carmeliet,et al. Amino acid levels determine metabolism and CYP450 function of hepatocytes and hepatoma cell lines , 2020, Nature Communications.
[8] Suowen Xu,et al. SIRT3 inhibits cardiac hypertrophy by regulating PARP-1 activity , 2020, Aging.
[9] Katherine Minter-Dykhouse,et al. Energy Metabolism Regulates Stem Cell Pluripotency , 2020, Frontiers in Cell and Developmental Biology.
[10] F. Villarroya,et al. SIRT3-mediated inhibition of FOS through histone H3 deacetylation prevents cardiac fibrosis and inflammation , 2020, Signal Transduction and Targeted Therapy.
[11] L. Zentilin,et al. Sirt3 deficiency shortens lifespan and impairs cardiac mitochondrial function rescued by Opa1 gene transfer. , 2019, Antioxidants & redox signaling.
[12] Haitao Li,et al. Molecular basis for hierarchical histone de-β-hydroxybutyrylation by SIRT3 , 2019, Cell Discovery.
[13] Deqing Hu,et al. Protein lysine de-2-hydroxyisobutyrylation by CobB in prokaryotes , 2019, Science Advances.
[14] Jiao Liu,et al. Von Hippel-Lindau Acts as a Metabolic Switch Controlling Nephron Progenitor Differentiation. , 2019, Journal of the American Society of Nephrology : JASN.
[15] K. Suszták,et al. DNMT1 in Six2 Progenitor Cells Is Essential for Transposable Element Silencing and Kidney Development. , 2019, Journal of the American Society of Nephrology : JASN.
[16] Mingzhou Chen,et al. SG formation relies on eIF4GI-G3BP interaction which is targeted by picornavirus stress antagonists , 2019, Cell Discovery.
[17] K. Cargill,et al. Metabolic requirements of the nephron , 2018, Pediatric Nephrology.
[18] Victor G. Puelles,et al. DNA Methyltransferase 1 Controls Nephron Progenitor Cell Renewal and Differentiation. , 2018, Journal of the American Society of Nephrology : JASN.
[19] P. Park,et al. EED, a member of the polycomb group, is required for nephron differentiation and the maintenance of nephron progenitor cells , 2018, Development.
[20] R. Roeder,et al. p300-Mediated Lysine 2-Hydroxyisobutyrylation Regulates Glycolysis. , 2018, Molecular cell.
[21] Yuwen Li,et al. Histone deacetylases 1 and 2 regulate the transcriptional programs of nephron progenitors and renal vesicles , 2018, Development.
[22] A. Benigni,et al. Sirtuins in Renal Health and Disease. , 2018, Journal of the American Society of Nephrology : JASN.
[23] Gary Siuzdak,et al. Metabolomics activity screening for identifying metabolites that modulate phenotype , 2018, Nature Biotechnology.
[24] Xiaoxi Meng,et al. Proteome-wide Analysis of Lysine 2-hydroxyisobutyrylation in Developing Rice (Oryza sativa) Seeds , 2017, Scientific Reports.
[25] Zhaohua Peng,et al. Proteome-wide Analysis of Lysine 2-hydroxyisobutyrylation in Developing Rice (Oryza sativa) Seeds , 2017, Scientific Reports.
[26] Jiao Liu,et al. Regulation of Nephron Progenitor Cell Self-Renewal by Intermediary Metabolism. , 2017, Journal of the American Society of Nephrology : JASN.
[27] G. Remuzzi,et al. Human mesenchymal stromal cells transplanted into mice stimulate renal tubular cells and enhance mitochondrial function , 2017, Nature Communications.
[28] James N. Hughes,et al. NAD Deficiency, Congenital Malformations, and Niacin Supplementation , 2017, The New England journal of medicine.
[29] Junbiao Dai,et al. 2-Hydroxyisobutyrylation on histone H4K8 is regulated by glucose homeostasis in Saccharomyces cerevisiae , 2017, Proceedings of the National Academy of Sciences.
[30] Clive Osmond,et al. A developmental approach to the prevention of hypertension and kidney disease: a report from the Low Birth Weight and Nephron Number Working Group , 2017, The Lancet.
[31] Jian Wang,et al. Landscape of the regulatory elements for lysine 2-hydroxyisobutyrylation pathway , 2017, Cell Research.
[32] B. Brenner,et al. The Impact of Kidney Development on the Life Course: A Consensus Document for Action , 2017, Nephron.
[33] Charles P. Lin,et al. Self-renewal of a purified Tie2+ hematopoietic stem cell population relies on mitochondrial clearance , 2016, Science.
[34] G. Schley,et al. The impact of hypoxia on nephrogenesis , 2016, Current opinion in nephrology and hypertension.
[35] P. Reynier,et al. Loss of functional OPA1 unbalances redox state: implications in dominant optic atrophy pathogenesis , 2016, Annals of clinical and translational neurology.
[36] G. Remuzzi,et al. Organoid Models and Applications in Biomedical Research , 2015, Nephron.
[37] S. Khochbin,et al. Histone Acylation beyond Acetylation: Terra Incognita in Chromatin Biology , 2015, Cell journal.
[38] B. Brenner,et al. Birth weight, malnutrition and kidney-associated outcomes—a global concern , 2015, Nature Reviews Nephrology.
[39] G. Remuzzi,et al. Sirtuin 3-dependent mitochondrial dynamic improvements protect against acute kidney injury. , 2015, The Journal of clinical investigation.
[40] Hening Lin,et al. Sirtuins in Epigenetic Regulation , 2015, Chemical reviews.
[41] Marco Craveiro,et al. Glucose and glutamine metabolism regulate human hematopoietic stem cell lineage specification. , 2014, Cell stem cell.
[42] Bing Ren,et al. Lysine 2-hydroxyisobutyrylation is a widely distributed active histone mark. , 2014, Nature chemical biology.
[43] N. Hamilton,et al. Global quantification of tissue dynamics in the developing mouse kidney. , 2014, Developmental cell.
[44] V. D’Agati,et al. The number of fetal nephron progenitor cells limits ureteric branching and adult nephron endowment. , 2014, Cell reports.
[45] Sean D. Mooney,et al. Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways , 2013, Proceedings of the National Academy of Sciences.
[46] M. Suematsu,et al. Distinct metabolic flow enables large-scale purification of mouse and human pluripotent stem cell-derived cardiomyocytes. , 2013, Cell stem cell.
[47] M. Suematsu,et al. Regulation of glycolysis by Pdk functions as a metabolic checkpoint for cell cycle quiescence in hematopoietic stem cells. , 2013, Cell stem cell.
[48] Jamie A Davies,et al. In vivo maturation of functional renal organoids formed from embryonic cell suspensions. , 2012, Journal of the American Society of Nephrology : JASN.
[49] D. Reinberg,et al. SIRT3 Functions in the Nucleus in the Control of Stress-Related Gene Expression , 2012, Molecular and Cellular Biology.
[50] P. Pandolfi,et al. A PML–PPAR-δ pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance , 2012, Nature Medicine.
[51] M. Hirschey,et al. Mitochondrial protein acetylation regulates metabolism. , 2012, Essays in biochemistry.
[52] M. Little,et al. Nephron formation adopts a novel spatial topology at cessation of nephrogenesis. , 2011, Developmental biology.
[53] Juan Carlos Izpisua Belmonte,et al. The metabolome of induced pluripotent stem cells reveals metabolic changes occurring in somatic cell reprogramming , 2011, Cell Research.
[54] Andre Terzic,et al. Somatic oxidative bioenergetics transitions into pluripotency-dependent glycolysis to facilitate nuclear reprogramming. , 2011, Cell metabolism.
[55] L. Guarente,et al. The SirT3 divining rod points to oxidative stress. , 2011, Molecular cell.
[56] S. Park,et al. Sirt3-mediated deacetylation of evolutionarily conserved lysine 122 regulates MnSOD activity in response to stress. , 2010, Molecular cell.
[57] Danica Chen,et al. Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation. , 2010, Cell metabolism.
[58] F. Alt,et al. SIRT3 deacetylates mitochondrial 3-hydroxy-3-methylglutaryl CoA synthase 2 and regulates ketone body production. , 2010, Cell metabolism.
[59] Huabing Zhang,et al. Sirtuin 3, a New Target of PGC-1α, Plays an Important Role in the Suppression of ROS and Mitochondrial Biogenesis , 2010, PloS one.
[60] J. McCoy,et al. Characterization of the murine SIRT3 mitochondrial localization sequence and comparison of mitochondrial enrichment and deacetylase activity of long and short SIRT3 isoforms , 2010, Journal of cellular biochemistry.
[61] S. Nigam,et al. How does the ureteric bud branch? , 2009, Journal of the American Society of Nephrology : JASN.
[62] N. Sundaresan,et al. SIRT3 Is a Stress-Responsive Deacetylase in Cardiomyocytes That Protects Cells from Stress-Mediated Cell Death by Deacetylation of Ku70 , 2008, Molecular and Cellular Biology.
[63] A. McMahon,et al. Six2 defines and regulates a multipotent self-renewing nephron progenitor population throughout mammalian kidney development. , 2008, Cell stem cell.
[64] W. C. Hallows,et al. Where in the cell is SIRT3?--functional localization of an NAD+-dependent protein deacetylase. , 2008, The Biochemical journal.
[65] J. N. Spelbrink,et al. The human SIRT3 protein deacetylase is exclusively mitochondrial. , 2008, The Biochemical journal.
[66] M. D. de Caestecker,et al. Fate mapping using Cited1-CreERT2 mice demonstrates that the cap mesenchyme contains self-renewing progenitor cells and gives rise exclusively to nephronic epithelia. , 2008, Developmental biology.
[67] H. A. Hartman,et al. Cessation of renal morphogenesis in mice. , 2007, Developmental biology.
[68] Eric Verdin,et al. Mammalian Sir2 Homolog SIRT3 Regulates Global Mitochondrial Lysine Acetylation , 2007, Molecular and Cellular Biology.
[69] D. Reinberg,et al. SirT3 is a nuclear NAD+-dependent histone deacetylase that translocates to the mitochondria upon cellular stress. , 2007, Genes & development.
[70] Andre Terzic,et al. Mitochondrial oxidative metabolism is required for the cardiac differentiation of stem cells , 2007, Nature Clinical Practice Cardiovascular Medicine.
[71] G. Dressler,et al. Six2 is required for suppression of nephrogenesis and progenitor renewal in the developing kidney , 2006, The EMBO journal.
[72] W. C. Hallows,et al. Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases , 2006, Proceedings of the National Academy of Sciences.
[73] S. Vainio,et al. Organogenesis: Coordinating early kidney development: lessons from gene targeting , 2002, Nature Reviews Genetics.
[74] S. Nigam,et al. In vitro branching tubulogenesis: implications for developmental and cystic disorders, nephron number, renal repair, and nephron engineering. , 1998, Kidney international.
[75] G. Géraud,et al. Early defect in branching morphogenesis of the ureteric bud in induced nephron deficit. , 1996, Kidney international.
[76] L. Cantley,et al. Regulation of mitogenesis, motogenesis, and tubulogenesis by hepatocyte growth factor in renal collecting duct cells. , 1994, The American journal of physiology.
[77] J. Bismuth,et al. Effects of birth on energy metabolism in the rat kidney. , 1988, The Biochemical journal.
[78] G. Striker,et al. Glomerulosclerosis and renal cysts in mice transgenic for the early region of SV40. , 1987, Kidney international.
[79] L. Saxén,et al. Early organogenesis of the kidney , 1987, Pediatric Nephrology.
[80] J. Ramalho-Santos,et al. Sirtuins in metabolism, stemness and differentiation. , 2017, Biochimica et biophysica acta. General subjects.
[81] A. McMahon. Development of the Mammalian Kidney. , 2016, Current topics in developmental biology.
[82] B. Schwer,et al. SIRT3 regulates mitochondrial protein acetylation and intermediary metabolism. , 2011, Cold Spring Harbor symposia on quantitative biology.