The utility of a ternary phase diagram in the discovery of new co-crystal forms

The construction of the ternary phase diagram urea–glutaric acid–water has led to the discovery of a new co-crystal form.

[1]  R. Davey,et al.  Making Co-crystals-The utility of ternary phase diagrams , 2007 .

[2]  W. Jones,et al.  Crystal Engineering of Organic Cocrystals by the Solid-State Grinding Approach , 2005 .

[3]  J. Bernstein,et al.  Solid-state nucleophilic aromatic substitution reaction of a carboxylic acid cocrystal , 1989 .

[4]  F. Toda,et al.  Charge-Transfer Complex Formation by Grinding Crystals of Donor and Acceptor , 1995 .

[5]  Koichi Tanaka,et al.  Host–guest complex formation by a solid–solid reaction , 1987 .

[6]  Sarah J. Nehm,et al.  Reaction crystallization of pharmaceutical molecular complexes. , 2006, Molecular pharmaceutics.

[7]  V. Videnova-Adrabińska.  Pre-designed structural building blocks of a (1:1) urea–glutaric acid co-crystal , 1995 .

[8]  M. C. Etter,et al.  Urea-glutaric acid (2∶1) structural aggregates as building blocks for crystal engineering , 1995 .

[9]  Sarah J. Nehm,et al.  Phase solubility diagrams of cocrystals are explained by solubility product and solution complexation , 2006 .

[10]  W. Jones,et al.  Mechanochemistry and co-crystal formation: effect of solvent on reaction kinetics. , 2002, Chemical communications.

[11]  Margaret C. Etter,et al.  Hydrogen-bond directed cocrystallization as a tool for designing acentric organic solids , 1989 .

[12]  William Jones,et al.  Selective polymorph transformation via solvent-drop grinding. , 2005, Chemical communications.

[13]  L. Fábián,et al.  Exploring cocrystal-cocrystal reactivity via liquid-assisted grinding: the assembling of racemic and dismantling of enantiomeric cocrystals. , 2006, Chemical communications.