Important non‐disease‐related determinants of exhaled nitric oxide levels in mild asthma – results from the Swedish GA2LEN study

Fractional exhaled nitric oxide (FeNO) has a potential clinical role in asthma management. Constitutive factors such as age, height and gender, as well as individual characteristics, such as IgE sensitization and smoking, affect the levels of FeNO in population‐based studies. However, their effect on FeNO in subjects with asthma has been scarcely studied.

[1]  J. Skripak Persistent Effects of Maternal Smoking During Pregnancy on Lung Function and Asthma in Adolescents , 2014, Pediatrics.

[2]  A. Malinovschi,et al.  FeNO as a predictor of asthma control improvement after starting inhaled steroid treatment. , 2014, Nitric oxide : biology and chemistry.

[3]  C. Janson,et al.  Alveolar and exhaled NO in relation to asthma characteristics – effects of correction for axial diffusion , 2014, Allergy.

[4]  I. Pavord,et al.  Current evidence and future research needs for FeNO measurement in respiratory diseases. , 2014, Respiratory medicine.

[5]  D. Jarvis,et al.  Geographical variation in the prevalence of sensitization to common aeroallergens in adults: the GA2LEN survey , 2014, Allergy.

[6]  Sang-Heon Cho,et al.  Reference Ranges and Determinant Factors for Exhaled Nitric Oxide in a Healthy Korean Elderly Population , 2014, Allergy, asthma & immunology research.

[7]  C. Janson,et al.  Asthma and physical activity--a population based study results from the Swedish GA(2)LEN survey. , 2013, Respiratory medicine.

[8]  M. Lekander,et al.  Anti-inflammatory treatment of atopic asthma guided by exhaled nitric oxide: a randomized, controlled trial. , 2013, The journal of allergy and clinical immunology. In practice.

[9]  C. Janson,et al.  Chronic rhinosinusitis in asthma is a negative predictor of quality of life: results from the Swedish GA2LEN survey , 2013, Allergy.

[10]  D. Youssef,et al.  The influence of leptin on Th1/Th2 balance in obese children with asthma* , 2013, Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia.

[11]  J. Donohue,et al.  Exhaled nitric oxide to predict corticosteroid responsiveness and reduce asthma exacerbation rates. , 2013, Respiratory medicine.

[12]  M. Mäkelä,et al.  Maternal smoking affects lung function and airway inflammation in young children with multiple-trigger wheeze. , 2013, The Journal of allergy and clinical immunology.

[13]  G. Roberts,et al.  Relationships between age of puberty onset and height at age 18 years in girls and boys , 2013, World Journal of Pediatrics.

[14]  A. Dozor,et al.  Relationship between Exhaled Nitric Oxide and Exposure to Low-Level Environmental Tobacco Smoke in Children with Asthma on Inhaled Corticosteroids , 2012, The Journal of asthma : official journal of the Association for the Care of Asthma.

[15]  C. Porsbjerg,et al.  The value of exhaled nitric oxide to identify asthma in smoking patients with asthma-like symptoms. , 2012, Respiratory Medicine.

[16]  R. Arens,et al.  Obesity-associated asthma in children: a distinct entity. , 2012, Chest.

[17]  D. Cook,et al.  Prenatal and Passive Smoke Exposure and Incidence of Asthma and Wheeze: Systematic Review and Meta-analysis , 2012, Pediatrics.

[18]  M. Thompson,et al.  Estrogen Increases Nitric-Oxide Production in Human Bronchial Epithelium , 2011, Journal of Pharmacology and Experimental Therapeutics.

[19]  Nicola A Hanania,et al.  Lebrikizumab treatment in adults with asthma. , 2011, The New England journal of medicine.

[20]  P. Gibson,et al.  Management of asthma in pregnancy guided by measurement of fraction of exhaled nitric oxide: a double-blind, randomised controlled trial , 2011, The Lancet.

[21]  Margaret W Leigh,et al.  An official ATS clinical practice guideline: interpretation of exhaled nitric oxide levels (FENO) for clinical applications. , 2011, American journal of respiratory and critical care medicine.

[22]  D. Jarvis,et al.  Reliability of EP3OS symptom criteria and nasal endoscopy in the assessment of chronic rhinosinusitis – a GA2LEN study , 2011, Allergy.

[23]  D. Jarvis,et al.  Early age at menarche, lung function, and adult asthma. , 2011, American journal of respiratory and critical care medicine.

[24]  J. Bousquet,et al.  Passive and active smoking and exhaled nitric oxide levels according to asthma and atopy in adults. , 2010, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

[25]  G. Roberts,et al.  Influence of atopy and asthma on exhaled nitric oxide in an unselected birth cohort study , 2010, Thorax.

[26]  M. Sears,et al.  Changes in exhaled nitric oxide related to estrogen and progesterone during the menstrual cycle. , 2009, Chest.

[27]  C. Janson,et al.  Both allergic and nonallergic asthma are associated with increased FENO levels, but only in never‐smokers , 2009, Allergy.

[28]  R. Hancox,et al.  Factors affecting exhaled nitric oxide measurements: the effect of sex , 2007, Respiratory research.

[29]  K. Torén,et al.  Height, age, and atopy are associated with fraction of exhaled nitric oxide in a large adult general population sample. , 2006, Chest.

[30]  S. Stick,et al.  Parental smoking increases exhaled nitric oxide in young children , 2006, European Respiratory Journal.

[31]  C. Janson,et al.  Effect of smoking on exhaled nitric oxide and flow-independent nitric oxide exchange parameters , 2006, European Respiratory Journal.

[32]  E. Vartiainen,et al.  Exhaled nitric oxide in healthy nonatopic school‐age children: Determinants and height‐adjusted reference values , 2006, Pediatric pulmonology.

[33]  C. Janson,et al.  IgE sensitisation in relation to flow-independent nitric oxide exchange parameters , 2006, Respiratory research.

[34]  D. Jarvis,et al.  Changes in active and passive smoking in the European Community Respiratory Health Survey , 2006, European Respiratory Journal.

[35]  J. Cowan,et al.  Use of exhaled nitric oxide measurements to guide treatment in chronic asthma. , 2005, The New England journal of medicine.

[36]  ATS/ERS recommendations for standardized procedures for the online and offline measurement of exhaled lower respiratory nitric oxide and nasal nitric oxide, 2005. , 2005, American journal of respiratory and critical care medicine.

[37]  Gert Folkerts,et al.  Nitric Oxide in Health and Disease of the Respiratory System , 2022 .

[38]  P. Montuschi,et al.  Dose-dependent onset and cessation of action of inhaled budesonide on exhaled nitric oxide and symptoms in mild asthma , 2002, Thorax.

[39]  D. Yates,et al.  Passive smoke inhalation decreases exhaled nitric oxide in normal subjects. , 2001, American journal of respiratory and critical care medicine.

[40]  A. Buist,et al.  Absence of relationship between tuberculin reactivity and atopy in BCG vaccinated young adults , 2000, Thorax.

[41]  G. Verleden,et al.  The effect of cigarette smoking on exhaled nitric oxide in mild steroid-naive asthmatics. , 1999, Chest.

[42]  J L Hankinson,et al.  Spirometric reference values from a sample of the general U.S. population. , 1999, American journal of respiratory and critical care medicine.

[43]  J. Kastner,et al.  Sex differences in concentrations of exhaled nitric oxide and plasma nitrate. , 1996, Life sciences.

[44]  John L. Hankinson,et al.  Standardization of Spirometry, 1994 Update. American Thoracic Society. , 1995, American journal of respiratory and critical care medicine.

[45]  O. Zetterström,et al.  Single-breath nitric oxide measurements in asthmatic patients and smokers , 1994, The Lancet.

[46]  J E Cotes,et al.  Lung volumes and forced ventilatory flows , 1993, European Respiratory Journal.

[47]  J E Cotes,et al.  Lung volumes and forced ventilatory flows. Report Working Party Standardization of Lung Function Tests, European Community for Steel and Coal. Official Statement of the European Respiratory Society. , 1993, The European respiratory journal. Supplement.

[48]  A. Buist Standardization of spirometry. , 1987, The American review of respiratory disease.