The correlation between alcohol consumption and reducing the age of cancer incidence in patients with this disease

Introduction: Cancer is one of the leading causes of death worldwide. Given that since 1988, the International Agency for Research on Cancer has identified alcohol as the first group of carcinogens that in the highest level of risk and in Khuzestan province there are limited studies on the relationship between alcohol and cancer. Therefore, the aim of this study was to determine the Correlation between alcohol consumption and reducing the age of cancer incidence in patients with this disease Resident in Khuzestan province from 2016 to 2018. Materials and Methods: This study is a retrospective cross-sectional analytical descriptive study. And included a survey of 2483 patients with various types of cancer Hospitalized in Shafa and Baghaei 2 Hospitals, resident of Ahwaz, Shoushtar, Abadan and Behbahan, which was conducted by nine researchers investigate their cases. Patients diagnosed with any cancer and referred to treatment centers in the aforementioned city from 2016 to 2018 were investigated and entered to study. All cancer patients were of different types in each age group and sexually diagnosed with the disease. Enter into the study and records that had medical diagnosis other than the disease, and files that were incompletely filled, were excluded. The data in this study included demographic, laboratory and clinical data of patients. Data were then entered into SPSS software version 20. Data were analyzed using descriptive, analytical, and significant level of P <0.05. Results: The study included 2483 cancer patients with an average 61.00±43.36 age of years of these, 1447 (58.2%) were female and the rest were male patients. In this study, 216 (8.6) had a history of alcohol consumption and the rest did not consume any. There was a significant relationship between sex with a history of alcohol consumption (p <0.0001). Also, there was a significant relationship between age and alcohol consumption (p = 0.001). Also, patients who consumed alcohol, compared to those who did not consume alcohol, had a lower average age, so we can say that alcohol reduces the age of incidence to cancer. Conclusion: In this study, a significant relationship was found between age and alcohol consumption. Also Patients who had consumed alcohol, compared to those who did not eat at all, they had a lower average age, so we can say that alcohol reduces the age of incidence to cancer. Therefore, it is necessary to follow up on the prevention of alcohol addiction and they should be treated after alcohol addiction, and it must be done preventive measures to prevent than incidence to cancer.

[1]  M. Madmoli,et al.  EVALUATION OF GI BLEEDING PREVALENCE AND ITS RELATED FACTORS IN DIABETIC PATIENTS HOSPITALIZED IN KHATAM-OL-ANBIA HOSPITAL DURING 2015-16: A RETROSPECTIVE STUDY , 2018 .

[2]  Moslem Moslemirad DIABETES AND THE RISK OF SUFFERING CARDIOVASCULAR DISEASES: A TWO-YEAR RETROSPECTIVE STUDY , 2018 .

[3]  M. Madmoli,et al.  THE RELATIONSHIP BETWEEN USING INSULIN AND SUFFERING ALZHEIMER'S DISEASE IN PATIENTS WITH DIABETES: A TWO-YEAR STUDY , 2018 .

[4]  S. Atashak,et al.  The Effect of High Intensity Interval Training on STAT-3 and Angiopoietin-1 Gene Expression, and tie-2 Protein in Mice with Breast Cancer , 2018 .

[5]  F. Rostami EVALUATION OF PREVALENCE OF DIABETIC FOOT ULCER AND ITS RELATED FACTORS IN DIABETIC PATIENTS ADMITTED TO KHATAM-OL-ANBIA HOSPITAL IN SHOUSHTAR DURING 2015-2016: A RETROSPECTIVE STUDY , 2018 .

[6]  Keeho Park,et al.  Type 1 diabetes mellitus and risk of cancer: a meta-analysis of observational studies , 2018, Japanese journal of clinical oncology.

[7]  W. Klein,et al.  Awareness of the Link between Alcohol Consumption and Cancer across the World: A Review , 2018, Cancer Epidemiology, Biomarkers & Prevention.

[8]  A. Feizi,et al.  A SURVEY ON THE FREQUENCY OF MODERATE AND SEVERE DRUG INTERACTIONS AND DURING OPERATION AMONG ELDERLY PATIENTS WITH CANCER UNDER CHEMOTHERAPY REFERRED TO IMAM KHOMEINI HOSPITAL, ARDEBIL 2015-16 , 2018 .

[9]  H. Boeing,et al.  Effect of diet on mortality and cancer recurrence among cancer survivors: a systematic review and meta-analysis of cohort studies , 2016, Nutrition reviews.

[10]  S. Chhatre,et al.  Association between age, substance use, and outcomes in Medicare enrollees with prostate cancer. , 2016, Journal of geriatric oncology.

[11]  M. Arefi,et al.  Prevalence of Death Anxiety in Patients with Breast Cancer in Kermanshah, 2015 , 2016 .

[12]  V. Budach,et al.  Patient and treatment-related risk factors for osteoradionecrosis of the jaw in patients with head and neck cancer. , 2016, Oral surgery, oral medicine, oral pathology and oral radiology.

[13]  A. Green,et al.  The mortality after surgery in primary lung cancer: results from the Danish Lung Cancer Registry. , 2016, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[14]  F. Pourfarzi,et al.  An Epidemiologic Study of Spatial and Temporal Patterns of Gastric Cancer in Ardabil )Years 2006- 2012( , 2015 .

[15]  M. Ehrenfeld,et al.  Osteoradionecrosis of the mandible: A ten year single-center retrospective study. , 2015, Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery.

[16]  G. O'leary,et al.  Impact of current smoking and alcohol consumption on gastrostomy duration in patients with head and neck cancer undergoing definitive chemoradiotherapy. , 2015, JAMA otolaryngology-- head & neck surgery.

[17]  S. Cai,et al.  Alcohol drinking and upper aerodigestive tract cancer mortality: a systematic review and meta-analysis. , 2014, Oral oncology.

[18]  A. Tjønneland,et al.  Pre‐diagnostic alcohol consumption and breast cancer recurrence and mortality: Results from a prospective cohort with a wide range of variation in alcohol intake , 2013, International journal of cancer.

[19]  C. Gourin,et al.  The effect of alcohol abuse and alcohol withdrawal on short‐term outcomes and cost of care after head and neck cancer surgery , 2012, The Laryngoscope.

[20]  J. Baron,et al.  Prediagnostic smoking history, alcohol consumption, and colorectal cancer survival , 2011, Cancer.

[21]  C. Sweeney,et al.  Alcohol consumption and breast cancer recurrence and survival among women with early-stage breast cancer: the life after cancer epidemiology study. , 2010, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[22]  P. Porter,et al.  Relationship between potentially modifiable lifestyle factors and risk of second primary contralateral breast cancer among women diagnosed with estrogen receptor-positive invasive breast cancer. , 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[23]  M. Chambers,et al.  Osteoradionecrosis of the mandible: treatment outcomes and factors influencing the progress of osteoradionecrosis. , 2009, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.

[24]  C. Dégi,et al.  Non-disclosure of cancer diagnosis: an examination of personal, medical, and psychosocial factors , 2009, Supportive Care in Cancer.

[25]  P. Rezaeifar,et al.  THE EPIDEMIOLOGY OF GASTROINTESTINAL CANCERS IN ELDERLY OF EAST-AZERBAIJAN PROVINCE (2006) , 2008 .

[26]  M. Spitz,et al.  Second primary tumors in patients with upper aerodigestive tract cancers: joint effects of smoking and alcohol (United States) , 2003, Cancer Causes & Control.

[27]  E. Feldman Modern Nutrition in Health and Disease , 1999 .

[28]  Moslem Moslemirad,et al.  Prevalence of Type 1 and Type 2 Diabetes and its Related Factors in Diabetic Patients Hospitalized in Khatam-ol-Anbia Hospital in Shoushtar, 2014-15: A Retrospective Study , 2018 .

[29]  Haider Saadoon Qasim Alhilfi,et al.  Epidemiological data of 1418 Cancer Cases of Inpatient in Al-Sadder Teaching Hospital, Misan Province from 2011-2018 (Surveillance Study) , 2018 .

[30]  Ryan S. Lee,et al.  The prevalence and risk factors associated with osteoradionecrosis of the jaw in oral and oropharyngeal cancer patients treated with intensity-modulated radiation therapy (IMRT): The Memorial Sloan Kettering Cancer Center experience. , 2017, Oral oncology.

[31]  H. Brenner,et al.  Alcohol consumption and survival of colorectal cancer patients : population-based study from Germany 1 , 2 , 2016 .

[32]  H. Hashemizadeh,et al.  RISK FACTORS AND THE MOST COMMON INITIAL SYMPTOMS OF ACUTE LYMPHOBLASTIC LEUKEMIA IN CHILDREN , 2011 .