Present status and perspectives of cell-based therapies for liver diseases.

[1]  T. Sugiyama,et al.  Human umbilical cord blood-derived cells differentiate into hepatocyte-like cells in the Fas-mediated liver injury model. , 2005, American journal of physiology. Gastrointestinal and liver physiology.

[2]  Toshio Miki,et al.  Stem Cell Characteristics of Amniotic Epithelial Cells , 2005, Stem cells.

[3]  R. Sarkar,et al.  Transplantation of endothelial cells corrects the phenotype in hemophilia A mice , 2005, Journal of thrombosis and haemostasis : JTH.

[4]  T. Cantz,et al.  Human cord blood stem cells generate human cytokeratin 18-negative hepatocyte-like cells in injured mouse liver. , 2005, The American journal of pathology.

[5]  M. Najimi,et al.  Cryopreserved Liver Cell Transplantation Controls Ornithine Transcarbamylase Deficient Patient While Awaiting Liver Transplantation , 2005, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[6]  A. Dhawan,et al.  Hepatocyte transplantation for metabolic liver disease: UK experience. , 2005, Journal of the Royal Society of Medicine.

[7]  Mei-jue Chen,et al.  Identification and characterization of engrafted human cells in human/goat xenogeneic transplantation chimerism. , 2005, DNA and cell biology.

[8]  N. Olson,et al.  Thromboelastography measurements of whole blood from factor VIII‐deficient mice supplemented with rFVIII , 2005, Haemophilia : the official journal of the World Federation of Hemophilia.

[9]  X. Chen,et al.  Diminution of toxic copper accumulation in toxic milk mice modeling Wilson disease by embryonic hepatocyte intrasplenic transplantation. , 2005, World journal of gastroenterology.

[10]  F. Oesch,et al.  Generation of human hepatocytes by stem cell technology: definition of the hepatocyte , 2005, Expert opinion on drug metabolism & toxicology.

[11]  James A. Hutchinson,et al.  Differentiation of in vitro-modified human peripheral blood monocytes into hepatocyte-like and pancreatic islet-like cells. , 2005, Gastroenterology.

[12]  M. Kusano,et al.  Intrasplenic Transplantation of Encapsulated Hepatocytes Decreases Mortality and Improves Liver Functions in Fulminant Hepatic Failure from 90% Partial Hepatectomy in Rats , 2005, Transplantation.

[13]  M. Manns,et al.  Acute liver failure: a message found under the skin , 2005, Postgraduate Medical Journal.

[14]  R. Jalan.  Acute liver failure: current management and future prospects. , 2005, Journal of hepatology.

[15]  Paolo Carraro,et al.  Isolated Hepatocyte Transplantation for Crigler-Najjar Syndrome Type 1 , 2005, Cell transplantation.

[16]  T. Kawaguchi,et al.  The Wilson disease protein ATP7B resides in the late endosomes with Rab7 and the Niemann-Pick C1 protein. , 2005, The American journal of pathology.

[17]  F. Oesch,et al.  Hepatocytes cultured in alginate microspheres: an optimized technique to study enzyme induction. , 2005, Toxicology.

[18]  S. Koenig,et al.  Liver Repopulation after Hepatocellular Transplantation: Integration and Interaction of Transplanted Hepatocytes in the Host , 2005, Cell transplantation.

[19]  N. Rosenthal,et al.  Human hepatocytes in mice receiving pre-immune injection with human cord blood cells. , 2004, Biochemical and biophysical research communications.

[20]  M. Rela,et al.  Hepatocyte transplantation for inherited factor VII deficiency. , 2004, Transplantation.

[21]  A. Reichenbach,et al.  In Vitro Cultured Islet‐Derived Progenitor Cells of Human Origin Express Human Albumin in Severe Combined Immunodeficiency Mouse Liver In Vivo , 2004, Stem cells.

[22]  M. Toner,et al.  Hepatic tissue engineering for adjunct and temporary liver support: Critical technologies , 2004 .

[23]  M. Manns,et al.  Regional and transient ischemia/reperfusion injury in the liver improves therapeutic efficacy of allogeneic intraportal hepatocyte transplantation in low-density lipoprotein receptor deficient Watanabe rabbits. , 2004, Journal of hepatology.

[24]  G. Almeida-Porada,et al.  Formation of human hepatocytes by human hematopoietic stem cells in sheep. , 2004, Blood.

[25]  M. Manns,et al.  Reevaluation of Bone Marrow-Derived Cells as a Source for Hepatocyte Regeneration , 2004, Cell transplantation.

[26]  P. Wernet,et al.  A New Human Somatic Stem Cell from Placental Cord Blood with Intrinsic Pluripotent Differentiation Potential , 2004, The Journal of experimental medicine.

[27]  M. Grompe,et al.  Myelomonocytic cells are sufficient for therapeutic cell fusion in liver , 2004, Nature Medicine.

[28]  M. Rela,et al.  ONE LIVER, THREE RECIPIENTS: SEGMENT IV FROM SPLIT-LIVER PROCEDURES AS A SOURCE OF HEPATOCYTES FOR CELL TRANSPLANTATION , 2004, Transplantation.

[29]  S. Baylin,et al.  Hematopoietic stem cells convert into liver cells within days without fusion , 2004, Nature Cell Biology.

[30]  A. Burlina.  Hepatocyte transplantation for inborn errors of metabolism , 2004, Journal of Inherited Metabolic Disease.

[31]  Klaus Pfeffer,et al.  Fusion of bone-marrow-derived cells with Purkinje neurons, cardiomyocytes and hepatocytes , 2003, Nature.

[32]  J. Seppen,et al.  Long-term correction of bilirubin UDPglucuronyltransferase deficiency in rats by in utero lentiviral gene transfer. , 2003, Molecular therapy : the journal of the American Society of Gene Therapy.

[33]  A. Edge,et al.  Route of hepatocyte delivery affects hepatocyte engraftment in the spleen. , 2003, Transplantation.

[34]  A. Moser,et al.  Hepatocyte transplantation in a 4-year-old girl with peroxisomal biogenesis disease: technique, safety, and metabolic follow-up. , 2003, Transplantation.

[35]  A. Nagler,et al.  HGF, SDF-1, and MMP-9 are involved in stress-induced human CD34+ stem cell recruitment to the liver. , 2003, The Journal of clinical investigation.

[36]  P. Hayes,et al.  Human cord blood-derived cells can differentiate into hepatocytes in the mouse liver with no evidence of cellular fusion. , 2003, Gastroenterology.

[37]  S. Strom,et al.  Isolated hepatocyte transplantation in an infant with a severe urea cycle disorder. , 2003, Pediatrics.

[38]  George McNamara,et al.  Albumin-expressing hepatocyte-like cells develop in the livers of immune-deficient mice that received transplants of highly purified human hematopoietic stem cells. , 2003, Blood.

[39]  J. Wingard,et al.  Transplanted Human Cord Blood Cells Give Rise to Hepatocytes in Engrafted Mice , 2003, Annals of the New York Academy of Sciences.

[40]  G. Vassilopoulos,et al.  Transplanted bone marrow regenerates liver by cell fusion , 2003, Nature.

[41]  C. Fuentealba,et al.  Animal models of copper-associated liver disease , 2003, Comparative hepatology.

[42]  S. Kakinuma,et al.  Human Umbilical Cord Blood as a Source of Transplantable Hepatic Progenitor Cells , 2003, Stem Cells.

[43]  J. Platt,et al.  Treatment of cirrhosis and liver failure in rats by hepatocyte xenotransplantation. , 2003, Gastroenterology.

[44]  S. Strom,et al.  Hepatocyte transplantation: new possibilities for therapy. , 2003, Gastroenterology.

[45]  E. Laconi,et al.  Principles of hepatocyte repopulation. , 2002, Seminars in cell & developmental biology.

[46]  M. Grompe,et al.  Kinetics of liver repopulation after bone marrow transplantation. , 2002, The American journal of pathology.

[47]  Masahiro Ito,et al.  Treatment of liver failure in rats with end‐stage cirrhosis by transplantation of immortalized hepatocytes , 2002, Hepatology.

[48]  M. Simon,et al.  C1qRp defines a new human stem cell population with hematopoietic and hepatic potential , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[49]  Catherine M. Verfaillie,et al.  Pluripotency of mesenchymal stem cells derived from adult marrow , 2002, Nature.

[50]  F. Oesch,et al.  Downregulation of beta2-microglobulin in human cord blood somatic stem cells after transplantation into livers of SCID-mice: an escape mechanism of stem cells? , 2002, Biochemical and biophysical research communications.

[51]  A. Granato,et al.  Hepatocyte transplantation as a treatment for glycogen storage disease type 1a , 2002, The Lancet.

[52]  F. Weizsäcker,et al.  Zelltherapie in der Hepatologie , 2001 .

[53]  N. Kobayashi,et al.  A reversibly immortalized human hepatocyte cell line as a source of hepatocyte‐based biological support , 2001, Addiction biology.

[54]  J F Elliott,et al.  Clinical outcomes and insulin secretion after islet transplantation with the Edmonton protocol. , 2001, Diabetes.

[55]  B. Vikram,et al.  Liver irradiation: a potential preparative regimen for hepatocyte transplantation. , 2001, International journal of radiation oncology, biology, physics.

[56]  A J Smith,et al.  Correction of liver disease by hepatocyte transplantation in a mouse model of progressive familial intrahepatic cholestasis. , 2000, Gastroenterology.

[57]  M. Manns,et al.  Emerging Therapies in Hepatology: Liver-Directed Gene Transfer and Hepatocyte Transplantation , 2000, Cells Tissues Organs.

[58]  I. Fox,et al.  Hepatocyte transplantation in rats with decompensated cirrhosis , 2000, Hepatology.

[59]  L. Mcgavran,et al.  Hepatocyte transplantation in acute liver failure , 2000, Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.

[60]  W. Mars,et al.  Bone marrow as a potential source of hepatic oval cells. , 1999, Science.

[61]  R. Fisher,et al.  Defining hepatocellular chimerism in a liver failure patient bridged with hepatocyte infusion. , 1999, Transplantation.

[62]  H. Esumi,et al.  Suppression of the 5' splice site mutation in the Nagase analbuminemic rat with mutated U1snRNA. , 1998, Biochemical and biophysical research communications.

[63]  S. Strom,et al.  Treatment of the Crigler-Najjar syndrome type I with hepatocyte transplantation. , 1998, The New England journal of medicine.

[64]  J. Goss,et al.  Adult liver transplantation for metabolic liver disease. , 1998, Clinics in liver disease.

[65]  R. McKay,et al.  In vitro-generated neural precursors participate in mammalian brain development. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[66]  P. Carmeliet,et al.  Mice lacking factor VII develop normally but suffer fatal perinatal bleeding , 1997, Nature.

[67]  M. Charron,et al.  Transplantation of human hepatocytes. , 1997, Transplantation proceedings.

[68]  R. Fisher,et al.  Hepatocyte transplantation as a bridge to orthotopic liver transplantation in terminal liver failure. , 1997, Transplantation.

[69]  A. Demetriou,et al.  Long-term correction of albumin levels in the Nagase analbuminemic rat: repopulation of the liver by transplanted normal hepatocytes under a regeneration response. , 1996, Cell transplantation.

[70]  J. Miyazaki,et al.  Correction of ornithine transcarbamylase deficiency in adult spf(ash) mice and in OTC-deficient human hepatocytes with recombinant adenoviruses bearing the CAG promoter. , 1996, Human gene therapy.

[71]  I. Nasonkin,et al.  In vivo gene therapy for hyperlipidemia: phenotypic correction in Watanabe rabbits by hepatic delivery of the rabbit LDL receptor gene. , 1995, The Journal of clinical investigation.

[72]  C. Habibullah,et al.  Human fetal hepatocyte transplantation in patients with fulminant hepatic failure. , 1994, Transplantation.

[73]  M. Kusano,et al.  Hepatocyte Transplantation in Man , 1992, Transplantation proceedings.

[74]  J. Wilson,et al.  Long-term improvement of hypercholesterolemia after ex vivo gene therapy in LDLR-deficient rabbits. , 1991, Science.

[75]  T. Starzl,et al.  Studies on mechanisms of augmentation of liver regeneration by cyclosporine and FK 506 , 1991, Hepatology.

[76]  S. Levenson,et al.  Transplantation of microcarrier‐attached hepatocytes into 90% partially hepatectomized rats , 1988, Hepatology.

[77]  B. Sundberg,et al.  Correction of hyperbilirubinemia in the glucuronyltransferase-deficient rat by intraportal hepatocyte transplantation. , 1977, Transplantation proceedings.

[78]  S. Strom,et al.  Hepatocyte transplantation for the treatment of human disease. , 1999, Seminars in liver disease.