Comparison of CGS 15943, ZM 241385 and SCH 58261 as antagonists at human adenosine receptors

[1]  B. Fredholm,et al.  Differences in the order of potency for agonists but not antagonists at human and rat adenosine A2A receptors. , 1999, Biochemical pharmacology.

[2]  K. Jacobson,et al.  Adenosine A3 receptors: novel ligands and paradoxical effects. , 1998, Trends in pharmacological sciences.

[3]  E. Ongini,et al.  [3H]‐SCH 58261 labelling of functional A2A adenosine receptors in human neutrophil membranes , 1998, British journal of pharmacology.

[4]  E. Ongini,et al.  Cardiovascular pharmacology of the A2A adenosine receptor antagonist, SCH 58261, in the rat. , 1998, The Journal of pharmacology and experimental therapeutics.

[5]  I. Biaggioni,et al.  Pharmacological characterization of adenosine A2B receptors: studies in human mast cells co-expressing A2A and A2B adenosine receptor subtypes. , 1998, Biochemical pharmacology.

[6]  B. Fredholm,et al.  Comparative pharmacology of human adenosine receptor subtypes – characterization of stably transfected receptors in CHO cells , 1997, Naunyn-Schmiedeberg's Archives of Pharmacology.

[7]  B. Fredholm,et al.  Characterization of human A2A adenosine receptors with the antagonist radioligand [3H]‐SCH 58261 , 1997, British journal of pharmacology.

[8]  Stephen P. H. Alexander,et al.  Characterization of the human brain putative A2B adenosine receptor expressed in Chinese hamster ovary (CHO.A2B4) cells , 1996, British journal of pharmacology.

[9]  K. Jacobson,et al.  Derivatives of the triazoloquinazoline adenosine antagonist (CGS15943) are selective for the human A3 receptor subtype. , 1996, Journal of medicinal chemistry.

[10]  B. Fredholm,et al.  Pharmacology of adenosine A2A receptors. , 1996, Trends in pharmacological sciences.

[11]  E. Ongini,et al.  Labeling of A2A adenosine receptors in human platelets by use of the new nonxanthine antagonist radioligand [3H]SCH 58261. , 1996, The Journal of pharmacology and experimental therapeutics.

[12]  S. Poucher,et al.  Pharmacodynamics of ZM 241385, a Potent A2a Adenosine Receptor Antagonist, after Enteric Administration in Rat, Cat and Dog , 1996, The Journal of pharmacy and pharmacology.

[13]  E. Ongini,et al.  The non-xanthine heterocyclic compound SCH 58261 is a new potent and selective A2a adenosine receptor antagonist. , 1996, The Journal of pharmacology and experimental therapeutics.

[14]  T. Palmer,et al.  Adenosine receptors , 1995, Neuropharmacology.

[15]  P. Singh,et al.  The in vitro pharmacology of ZM 241385, a potent, non‐xanthine, A2a selective adenosine receptor antagonist , 1995, British journal of pharmacology.

[16]  G. Stiles,et al.  Adenosine receptor subtypes: characterization and therapeutic regulation. , 1995, Annual review of pharmacology and toxicology.

[17]  Stefano Manfredini,et al.  Synthesis of new pyrazolo[4,3-e]1,2,4-triazolo[1,5-c] pyrimidine and 1,2,3-triazolo[4,5-e]1,2,4-triazolo[1,5-c] pyrimidine displaying potent and selective activity as A2a adenosine receptor antagonists. , 1994 .

[18]  J. Linden.  Cloned adenosine A3 receptors: pharmacological properties, species differences and receptor functions. , 1994, Trends in pharmacological sciences.

[19]  J. Linden,et al.  Molecular Cloning and Characterization of the Human A_3 Adenosine Receptor , 1993 .

[20]  M. Williams,et al.  Characterization of the binding of a novel nonxanthine adenosine antagonist radioligand, [3H]CGS 15943, to multiple affinity states of the adenosine A1 receptor in the rat cortex. , 1991, Molecular pharmacology.

[21]  B. Fredholm,et al.  A modification of a protein-binding method for rapid quantification of cAMP in cell-culture supernatants and body fluid. , 1990, Analytical biochemistry.

[22]  D Rodbard,et al.  Ligand: a versatile computerized approach for characterization of ligand-binding systems. , 1980, Analytical biochemistry.

[23]  Y. Cheng,et al.  Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction. , 1973, Biochemical pharmacology.

[24]  O. H. Lowry,et al.  Protein measurement with the Folin phenol reagent. , 1951, The Journal of biological chemistry.