Livedoid vasculopathy (LV) associated with sticky platelets syndrome type 3 (SPS type 3) and enhanced activity of plasminogen activator inhibitor (PAI‐1) anomalies

We report the case of a 12-year-old girl Mexican mestizo, who had for the past six months a red linear pattern with several painful ulcerations in both extremities and subsequent white porcelain-like atrophy of the skin (Fig. 1a). A clinical diagnosis of atrophy blanche was made, and on histology grounds thrombosis of dermal arterioles, with only scattered mononuclear cells near the affected arterioles. The absence of polymorphonuclear cells, as well as the lack of leukocytoclasia in the blood vessels, was noteworthy (Fig. 2). Routine laboratory work was unremarkable, and a thrombophilia profile was performed (Table 1). Two anomalies were found, leading to permanent anti-aggregation therapy with acetylsalicylic acid (81 mg) daily, obtaining a full recovery after four months (Fig. 1b). There was no family history of thrombotic events. Discussion