From Anatomic Standardization Analysis of Perfusion SPECT Data to Perfusion Pattern Modelling

Our objective being to model SPECT brain perfusion patterns, the purpose of this study was to characterize inter-individual functional variability among a population of SPECT data. From perfusion measurements performed on anatomically standardized SPECT, we proposed to use correspondence analysis and hierarchical clustering to explore the structure of statistical dependencies among these measurements. The method was applied to study two perfusion patterns, namely normal perfusion and ictal perfusion as observed in temporal lobe epilepsy.

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