Mdr1 Transfection Causes Enhanced Apoptosis by Paclitaxel: An Effect Independent of Drug Efflux Function of P-Glycoprotein
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[1] J. Au,et al. Apoptosis: A New Pharmacodynamic Endpoint , 1997, Pharmaceutical Research.
[2] N. Millenbaugh,et al. Cytostatic and Apoptotic Effects of Paclitaxel in Human Ovarian Tumors , 2004, Pharmaceutical Research.
[3] L. Kèlland,et al. Comparative in vitro cytotoxicity of taxol and Taxotere against cisplatin-sensitive and-resistant human ovarian carcinoma cell lines , 2004, Cancer Chemotherapy and Pharmacology.
[4] M. Wientjes,et al. Computational model of intracellular pharmacokinetics of paclitaxel. , 2000, The Journal of pharmacology and experimental therapeutics.
[5] M. Wientjes,et al. Relationship between paclitaxel activity and pathobiology of human solid tumors. , 1998, Clinical cancer research : an official journal of the American Association for Cancer Research.
[6] Jie Lu,et al. Cytostatic and apoptotic effects of paclitaxel in human breast tumors , 1998, Cancer Chemotherapy and Pharmacology.
[7] M. Wientjes,et al. Pharmacodynamics of immediate and delayed effects of paclitaxel: role of slow apoptosis and intracellular drug retention. , 1998, Cancer research.
[8] G. Giaccone,et al. Effects of tubulin-inhibiting agents in human lung and breast cancer cell lines with different multidrug resistance phenotypes. , 1998, Oncology reports.
[9] J. L. Au,et al. Differential time dependency of antiproliferative and apoptotic effects of taxol in human prostate tumors. , 1997, Urologic oncology.
[10] John Calvin Reed,et al. Co-expression of several molecular mechanisms of multidrug resistance and their significance for paclitaxel cytotoxicity in human AML HL-60 cells , 1997, Leukemia.
[11] A. Monks,et al. Resistance to paclitaxel mediated by P-glycoprotein can be modulated by changes in the schedule of administration , 1997, Cancer Chemotherapy and Pharmacology.
[12] Jessie L.-S. Au,et al. Pharmacologic effects of paclitaxel in human bladder tumors , 1997, Cancer Chemotherapy and Pharmacology.
[13] M. Wientjes,et al. Pharmacodynamics of taxol in human head and neck tumors. , 1996, Cancer research.
[14] T. Skovsgaard,et al. Cellular resistance to anthracyclines. , 1996, General pharmacology.
[15] W. B. Derry,et al. Mitotic block induced in HeLa cells by low concentrations of paclitaxel (Taxol) results in abnormal mitotic exit and apoptotic cell death. , 1996, Cancer research.
[16] F. Nathan,et al. Gene therapy for human cancer: an essay for clinicians. , 1996, Seminars in oncology.
[17] G. Hortobagyi,et al. Single-agent paclitaxel for the treatment of breast cancer: an overview. , 1996, Seminars in oncology.
[18] M. Haber,et al. Altered Expression of M2, the Class II -Tubulin Isotype, in a Murine J774.2 Cell Line with a High Level of Taxol Resistance (*) , 1995, The Journal of Biological Chemistry.
[19] M. Relling,et al. Clinical Pharmacokinetics of Paclitaxel , 1994, Clinical pharmacokinetics.
[20] K. Bhalla,et al. Characterization of a human myeloid leukemia cell line highly resistant to taxol. , 1994, Leukemia.
[21] M. Jordan,et al. Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[22] O. Fardel,et al. Expression of the multidrug resistance-associated P-glycoprotein (P-170) in 59 cases of de novo acute lymphoblastic leukemia: prognostic implications. , 1993, Blood.
[23] W. Mellado,et al. Taxol: Mechanisms of Action and Resistance a , 1986, Journal of the National Cancer Institute. Monographs.
[24] B. Monsarrat,et al. Taxol: pharmacology, metabolism and clinical implications. , 1993, Cancer surveys.
[25] G. Peters,et al. Growth, morphology and chemosensitivity studies on postconfluent cells cultured in 'V'-bottomed microtiter plates. , 1992, British Journal of Cancer.
[26] K. Danenberg,et al. Quantitation of thymidylate synthase, dihydrofolate reductase, and DT-diaphorase gene expression in human tumors using the polymerase chain reaction. , 1992, Cancer research.
[27] S. Horwitz,et al. Mechanism of action of taxol. , 1992, Trends in pharmacological sciences.
[28] K. Cowan,et al. Multidrug resistance in cells transfected with human genes encoding a variant P-glycoprotein and glutathione S-transferase-pi. , 1990, Molecular pharmacology.
[29] M. Tanimoto,et al. Increased P‐glycoprotein expression and multidrug‐resistant gene (mdr1) amplification are infrequently found in fresh acute leukemia cells. Sequential analysis of 15 cases at initial presentation and relapsed stage , 1989, Cancer.
[30] 伊藤 良則. Increased P-glycoprotein expression and multidrug-resistant gene (mdr1) amplification are infrequently found in fresh acute leukemia cells sequential analysis of 15 cases at initial presentation and relapsed stage , 1989 .
[31] I. Ringel,et al. Taxol is converted to 7-epitaxol, a biologically active isomer, in cell culture medium. , 1987, The Journal of pharmacology and experimental therapeutics.
[32] W. Mellado,et al. Taxol: mechanisms of action and resistance. , 1986, Annals of the New York Academy of Sciences.
[33] P. Schiff,et al. Taxol assembles tubulin in the absence of exogenous guanosine 5'-triphosphate or microtubule-associated proteins. , 1981, Biochemistry.