Optimal control of heart rate during treadmill exercise

Summary Feedback control of heart rate (HR) for treadmills is important for exercise intensity specification and prescription. This work aimed to formulate HR control within a stochastic optimal control framework and to experimentally evaluate controller performance. A quadratic cost function is developed and linked to quantitative performance outcome measures, namely, root-mean-square tracking error and average control signal power. An optimal polynomial systems design is combined with frequency-domain analysis of feedback loop properties, with focus on the input sensitivity function, which governs the response to broad-spectrum HR variability disturbances. These, in turn, are modelled using stochastic process theory. A simple and approximate model of HR dynamics was used for the linear time-invariant controller design. Twelve healthy male subjects were recruited for comparative experimental evaluation of 3 controllers, giving 36 tests in total. The mean root-mean-square tracking error for the optimal controllers was around 2.2 beats per minute. Significant differences were observed in average control signal power for 2 different settings of the control weighting (mean power 22.6 vs 62.5×10−4 m2/s2, high vs low setting, p=2.3×10−5). The stochastic optimal control framework provides a suitable method for attainment of high-precision, stable, and robust control of HR during treadmill exercise. The control weighting can be used to set the balance between regulation accuracy and control signal intensity, and it has a clear and systematic influence on the shape of the input sensitivity function. Future work should extend the problem formulation to encompass low-pass compensator and input sensitivity characteristics.

[1]  Karl Johan Åström,et al.  Computer-Controlled Systems: Theory and Design , 1984 .

[2]  Will G. Hopkins,et al.  Effects of Low-Volume High-Intensity Interval Training (HIT) on Fitness in Adults: A Meta-Analysis of Controlled and Non-Controlled Trials , 2014, Sports Medicine.

[3]  Michael J. Grimble,et al.  Optimal Control and Stochastic Estimation: Theory and Applications , 1988 .

[4]  B. Franklin,et al.  American College of Sports Medicine position stand. Quantity and quality of exercise for developing and maintaining cardiorespiratory, musculoskeletal, and neuromotor fitness in apparently healthy adults: guidance for prescribing exercise. , 2011, Medicine and science in sports and exercise.

[5]  Kenneth J. Hunt,et al.  Feedback control of heart rate during outdoor running: A smartphone implementation , 2016, Biomed. Signal Process. Control..

[6]  Andrey V. Savkin,et al.  Nonlinear Modeling and Control of Human Heart Rate Response During Exercise With Various Work Load Intensities , 2008, IEEE Transactions on Biomedical Engineering.

[7]  A. Malliani,et al.  Heart rate variability. Standards of measurement, physiological interpretation, and clinical use , 1996 .

[8]  Cristiano Maria Verrelli,et al.  Nonlinear Control Techniques for the Heart Rate Regulation in Treadmill Exercises , 2012, IEEE Transactions on Biomedical Engineering.

[9]  J. Coombes,et al.  The Impact of High-Intensity Interval Training Versus Moderate-Intensity Continuous Training on Vascular Function: a Systematic Review and Meta-Analysis , 2015, Sports Medicine.

[10]  Mark A Williams,et al.  Aerobic Exercise Intensity Assessment and Prescription in Cardiac Rehabilitation: A JOINT POSITION STATEMENT OF THE EUROPEAN ASSOCIATION FOR CARDIOVASCULAR PREVENTION AND REHABILITATION, THE AMERICAN ASSOCIATION OF CARDIOVASCULAR AND PULMONARY REHABILITATION, AND THE CANADIAN ASSOCIATION OF CARDIAC , 2012, Journal of cardiopulmonary rehabilitation and prevention.

[11]  T Shishido,et al.  Development of a servo-controller of heart rate using a treadmill. , 1999, Japanese circulation journal.

[12]  G. Tenenbaum,et al.  Age-related maximal heart rate: examination and refinement of prediction equations. , 2015, The Journal of sports medicine and physical fitness.

[13]  Kenneth J. Hunt Stochastic Optimal Control Theory with Application in Self-Tuning Control , 1989 .

[14]  Bruce A. Francis,et al.  The internal model principle of control theory , 1976, Autom..

[15]  Kenneth J. Hunt,et al.  Heart rate control during treadmill exercise using input-sensitivity shaping for disturbance rejection of very-low-frequency heart rate variability , 2016, Biomed. Signal Process. Control..

[16]  P. Thompson,et al.  ACSM's Guidelines for Exercise Testing and Prescription , 1995 .

[17]  K. Hunt,et al.  Identification of heart rate dynamics during moderate-to-vigorous treadmill exercise , 2015, BioMedical Engineering OnLine.

[18]  Kenneth J. Hunt,et al.  Comparison of linear and nonlinear feedback control of heart rate for treadmill running , 2016 .

[19]  S. Cerutti,et al.  Advances in heart rate variability signal analysis: joint position statement by the e-Cardiology ESC Working Group and the European Heart Rhythm Association co-endorsed by the Asia Pacific Heart Rhythm Society. , 2015, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

[20]  Andrew M Jones,et al.  Aerobic exercise intensity assessment and prescription in cardiac rehabilitation: a joint position statement of the European Association for Cardiovascular Prevention and Rehabilitation, the American Association of Cardiovascular and Pulmonary Rehabilitation and the Canadian Association of Cardiac R , 2013, European journal of preventive cardiology.

[21]  Andrey V. Savkin,et al.  Optimizing Heart Rate Regulation for Safe Exercise , 2010, Annals of Biomedical Engineering.