The liquid/liquid-waveguide-based absorption sensor

A light absorption sensor is based on phenomena of light absorption between in two flow stream layers with different refractive index in liquid/liquid (L2) waveguide in this letter. The diffusion between the core and the cladding forms the tapered L2 waveguide sensor. The taper can be controlled by the flow rates of the core and the cladding layers. The absorption sensor is fabricated using PDMS onto a microfluidic chip, which chip size is 3.5cm × 3cm and the absorption length is 2cm. Two different aqueous dye solutions such as rhodamin 6G and methylene blue are measured and approved by the experimental results of the absorption sensor. The limitation of detection is 0.5ng/mL for rhodamin 6G and 0.16ng/mL for methylene blue. The L2 waveguide absorption sensor has high potential usage for the biological, chemical and medical measurement applications.

[1]  J. Murphy,et al.  Evanescent wave absorption spectroscopy using multimode fibers , 1990 .

[2]  Ai Qun Liu,et al.  A liquid waveguide based evanescent wave sensor integrated onto a microfluidic chip , 2008 .

[3]  B. Packard,et al.  Resolution of absorption spectra of rhodamine 6G aggregates in aqueous solution using the law of mass action , 1997 .

[4]  W. M. Haynes CRC Handbook of Chemistry and Physics , 1990 .

[5]  Kathleen Richardson,et al.  Fabrication and testing of planar chalcogenide waveguide integrated microfluidic sensor. , 2007, Optics express.

[6]  R. Gauthier,et al.  Theoretical and experimental considerations for a single-mode fiber-optic bend-type sensor. , 1997, Applied optics.

[7]  Sindy K. Y. Tang,et al.  Dynamically reconfigurable liquid-core liquid-cladding lens in a microfluidic channel. , 2008, Lab on a chip.

[8]  G. Whitesides,et al.  Dynamic control of liquid-core/liquid-cladding optical waveguides , 2004, (CLEO). Conference on Lasers and Electro-Optics, 2005..

[9]  A. Mignani,et al.  Evanescent Wave Absorption Spectroscopy by Means of Bi-Tapered Multimode Optical Fibers , 1998 .

[10]  A. Liu,et al.  Label-free detection with micro optical fluidic systems (MOFS): a review , 2008, Analytical and bioanalytical chemistry.

[11]  Clifford R. Pollock Fundamentals of Optoelectronics , 1994 .

[12]  Larry L Hench,et al.  Effect of taper geometries and launch angle on evanescent wave penetration depth in optical fibers. , 2005, Biosensors & bioelectronics.

[13]  George M. Whitesides,et al.  Integrated fluorescent light source for optofluidic applications , 2005 .

[14]  George M Whitesides,et al.  Arrays and cascades of fluorescent liquid-liquid waveguides: broadband light sources for spectroscopy in microchannels. , 2005, Analytical chemistry.