Non-coding RNA-Mediated N6-Methyladenosine (m6A) deposition: A pivotal regulator of cancer, impacting key signaling pathways in carcinogenesis and therapy response

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[2]  Guo Ji,et al.  METTL3-mediated m6A modification of lncRNA SNHG3 accelerates gastric cancer progression by modulating miR-186-5p/cyclinD2 axis , 2023, International journal of immunopathology and pharmacology.

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[7]  Yi-Juan Zhang,et al.  N 6‐methyladenosine‐modified circFUT8 competitively interacts with YTHDF2 and miR‐186‐5p to stabilize FUT8 mRNA to promote malignant progression in lung adenocarcinoma , 2023, Thoracic cancer.

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[10]  Yan Lin,et al.  m6A-Mediated Biogenesis of circDDIT4 Inhibits Prostate Cancer Progression by Sequestrating ELAVL1/HuR , 2023, Molecular cancer research : MCR.

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[18]  Yanqing Huang,et al.  METTL3‐mediated m6A modification of pri‐miR‐148a‐3p affects prostate cancer progression by regulating TXNIP , 2023, Environmental toxicology.

[19]  Shou-Ching Tang,et al.  Enhancement of TKI sensitivity in lung adenocarcinoma through m6A-dependent translational repression of Wnt signaling by circ-FBXW7 , 2023, Molecular Cancer.

[20]  Jingting Jiang,et al.  ALKBH5/YTHDF2‐mediated m6A modification of circAFF2 enhances radiosensitivity of colorectal cancer by inhibiting Cullin neddylation , 2023, Clinical and translational medicine.

[21]  Chun-Peng Zhang,et al.  Circular RNA circ_KIAA1429 accelerates hepatocellular carcinoma progression via the miR-133a-3p/high mobility group AT-hook 2 (HMGA2) axis in an m6A-dependent manner , 2023, Human Cell.

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[27]  Yihang Guo,et al.  METTL3-Modulated circUHRF2 Promotes Colorectal Cancer Stemness and Metastasis through Increasing DDX27 mRNA Stability by Recruiting IGF2BP1 , 2023, Cancers.

[28]  Feng Qi,et al.  CSNK1D-mediated phosphorylation of HNRNPA2B1 induces miR-25-3p/miR-93-5p maturation to promote prostate cancer cell proliferation and migration through m6A-dependent manner , 2023, Cellular and Molecular Life Sciences.

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[30]  Fei Wang,et al.  N6-methyladenine-mediated aberrant activation of the lncRNA SOX2OT-GLI1 loop promotes non-small-cell lung cancer stemness , 2023, Cell death discovery.

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[32]  Ying Sun,et al.  m6A-enriched lncRNA LINC00839 promotes tumor progression by enhancing TAF15-mediated transcription of amine oxidase AOC1 in nasopharyngeal carcinoma , 2023, The Journal of biological chemistry.

[33]  E. Zhang,et al.  LncRNA LINC00969 promotes acquired gefitinib resistance by epigenetically suppressing of NLRP3 at transcriptional and posttranscriptional levels to inhibit pyroptosis in lung cancer , 2023, Cell death & disease.

[34]  Lirong Liu,et al.  LncRNA GAS5 regulated by FTO-mediated m6A demethylation promotes autophagic cell death in NSCLC by targeting UPF1/BRD4 axis , 2023, Molecular and cellular biochemistry.

[35]  Shusen Zheng,et al.  m6A-modification regulated circ-CCT3 acts as the sponge of miR-378a-3p to promote hepatocellular carcinoma progression , 2023, Epigenetics.

[36]  Xiu-ming Lu,et al.  LncRNA CACNA1G-AS1 up-regulates FTH1 to inhibit ferroptosis and promote malignant phenotypes in ovarian cancer cells , 2023, Oncology research.

[37]  Fengjuan Wu,et al.  LncRNA DGUOK-AS1 facilitates non-small cell lung cancer growth and metastasis through increasing TRPM7 stability via m6A modification. , 2023, Translational oncology.

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[40]  Junjie Xiao,et al.  RNA m6A-Regulated circ-ZNF609 Suppression Ameliorates Doxorubicin-Induced Cardiotoxicity by Upregulating FTO , 2023, JACC. Basic to translational science.

[41]  Weihua Luo,et al.  m6A-modified circRNA MYO1C participates in the tumor immune surveillance of pancreatic ductal adenocarcinoma through m6A/PD-L1 manner , 2023, Cell Death & Disease.

[42]  Wei Cui,et al.  HNRNPA2B1-Mediated MicroRNA-92a Upregulation and Section Acts as a Promising Noninvasive Diagnostic Biomarker in Colorectal Cancer , 2023, Cancers.

[43]  Yang Zhao,et al.  METTL3-mediated Hsa_circ_0000390 downregulation enhances the proliferation, migration, and invasion of colorectal cancer cells by increasing Notch1 expression , 2023, Human Cell.

[44]  Chengan Xu,et al.  Establishment and evaluation of an early prediction model of hepatorenal syndrome in patients with decompensated hepatitis B cirrhosis , 2023, BMC Gastroenterology.

[45]  Chuan Wang,et al.  Characterization of circSCL38A1 as a novel oncogene in bladder cancer via targeting ILF3/TGF-β2 signaling axis , 2023, Cell Death & Disease.

[46]  Langqing Sheng,et al.  WTAP-mediated m6A modification on circCMTM3 inhibits hepatocellular carcinoma ferroptosis by recruiting IGF2BP1 to increase PARK7 stability. , 2022, Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.

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[48]  Shoubin Cui.  METTL3‐mediated m6A modification of lnc RNA RHPN1‐AS1 enhances cisplatin resistance in ovarian cancer by activating PI3K/AKT pathway , 2022, Journal of clinical laboratory analysis.

[49]  Zehua Wang,et al.  Identification of miR‐30c‐5p as a tumor suppressor by targeting the m6A reader HNRNPA2B1 in ovarian cancer , 2022, Cancer medicine.

[50]  Jintao Wang,et al.  Prediction of prognosis, immune infiltration and immunotherapy response with N6-methyladenosine-related lncRNA clustering patterns in cervical cancer , 2022, Scientific Reports.

[51]  Hong-Hui Liu,et al.  Bioinformatics analysis of markers based on m6A related to prognosis combined with immune invasion of renal clear cell carcinoma , 2022, Cell biology international.

[52]  Zhang Zhaofeng,et al.  METTL3/LINC00662/miR-186-5p feedback loop regulates docetaxel resistance in triple negative breast cancer , 2022, Scientific Reports.

[53]  D. Zheng,et al.  N6-methyladenosine-modified circular RNA QSOX1 promotes colorectal cancer resistance to anti-CTLA-4 therapy through induction of intratumoral regulatory T cells. , 2022, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.

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[56]  Jingwen Liu,et al.  m^6A-modified circFOXK2 targets GLUT1 to accelerate oral squamous cell carcinoma aerobic glycolysis , 2022, Cancer Gene Therapy.

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[59]  Quanjiao Chen,et al.  N6-methyladenosine modification of circ_0003215 suppresses the pentose phosphate pathway and malignancy of colorectal cancer through the miR-663b/DLG4/G6PD axis , 2022, Cell Death & Disease.

[60]  X. Zu,et al.  m6A-induced lncDBET promotes the malignant progression of bladder cancer through FABP5-mediated lipid metabolism , 2022, Theranostics.

[61]  Jia Zeng,et al.  ALKBH5-mediated m6A modification of circCCDC134 facilitates cervical cancer metastasis by enhancing HIF1A transcription , 2022, Journal of Experimental & Clinical Cancer Research.

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[63]  E. Nice,et al.  Hypoxia-induced lncRNA STEAP3-AS1 activates Wnt/β-catenin signaling to promote colorectal cancer progression by preventing m6A-mediated degradation of STEAP3 mRNA , 2022, Molecular cancer.

[64]  Xiao Huang,et al.  m6A-Related lncRNA Signature Is Involved in Immunosuppression and Predicts the Patient Prognosis of the Age-Associated Ovarian Cancer , 2022, Journal of immunology research.

[65]  Hai Hu,et al.  m6A-Related lncRNAs Predict Overall Survival of Patients and Regulate the Tumor Immune Microenvironment in Osteosarcoma , 2022, Computational intelligence and neuroscience.

[66]  A. Fatica,et al.  Multiple Roles of m6A RNA Modification in Translational Regulation in Cancer , 2022, International journal of molecular sciences.

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[71]  Y. Wang,et al.  CircGPR137B/miR-4739/FTO feedback loop suppresses tumorigenesis and metastasis of hepatocellular carcinoma , 2022, Molecular cancer.

[72]  Q. Zhan,et al.  The m6A-induced lncRNA CASC8 promotes proliferation and chemoresistance via upregulation of hnRNPL in esophageal squamous cell carcinoma , 2022, International journal of biological sciences.

[73]  Weizhang Xu,et al.  Circular RNA circPOLR2A promotes clear cell renal cell carcinoma progression by facilitating the UBE3C-induced ubiquitination of PEBP1 and, thereby, activating the ERK signaling pathway , 2022, Molecular cancer.

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[76]  Linfeng Li,et al.  m6A methyltransferase METTL3-induced lncRNA SNHG17 promotes lung adenocarcinoma gefitinib resistance by epigenetically repressing LATS2 expression , 2022, Cell Death & Disease.

[77]  Yongquan Wang,et al.  Circular RNA circ‐TNPO3 inhibits clear cell renal cell carcinoma metastasis by binding to IGF2BP2 and destabilizing SERPINH1 mRNA , 2022, Clinical and translational medicine.

[78]  F. An,et al.  CircEZH2/miR-133b/IGF2BP2 aggravates colorectal cancer progression via enhancing the stability of m6A-modified CREB1 mRNA , 2022, Molecular cancer.

[79]  Shujuan Wang,et al.  Tumor-suppressive MEG3 induces microRNA-493-5p expression to reduce arabinocytosine chemoresistance of acute myeloid leukemia cells by downregulating the METTL3/MYC axis , 2022, Journal of translational medicine.

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[83]  Han Yan,et al.  Construction of m6A-Related lncRNA Prognostic Signature Model and Immunomodulatory Effect in Glioblastoma Multiforme , 2022, Frontiers in Oncology.

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[85]  Minmin Shi,et al.  LncRNA-PACERR induces pro-tumour macrophages via interacting with miR-671-3p and m6A-reader IGF2BP2 in pancreatic ductal adenocarcinoma , 2022, Journal of Hematology & Oncology.

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[95]  Hua Xiao,et al.  The N6-methyladenosine modification of circALG1 promotes the metastasis of colorectal cancer mediated by the miR-342-5p/PGF signalling pathway , 2022, Molecular cancer.

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[100]  Xiaoyu Chen,et al.  METTL14-mediated m6A modification of circORC5 suppresses gastric cancer progression by regulating miR-30c-2-3p/AKT1S1 axis , 2022, Molecular cancer.

[101]  Xue Bai,et al.  LncRNA UCA1 Promotes the Progression of AML by Upregulating the Expression of CXCR4 and CYP1B1 by Affecting the Stability of METTL14 , 2022, Journal of oncology.

[102]  Hao Yu,et al.  MicroRNA-135 inhibits initiation of epithelial-mesenchymal transition in breast cancer by targeting ZNF217 and promoting m6A modification of NANOG , 2022, Oncogene.

[103]  Jing Liu,et al.  m6A-related lncRNAs predict prognosis and indicate immune microenvironment in acute myeloid leukemia , 2022, Scientific Reports.

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[106]  Wanying Fu,et al.  piRNA-14633 promotes cervical cancer cell malignancy in a METTL14-dependent m6A RNA methylation manner , 2022, Journal of translational medicine.

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[117]  Sumei Li,et al.  Effect of m6A methyltransferase METTL3 ‐mediated MALAT1/E2F1/AGR2 axis on adriamycin resistance in breast cancer , 2021, Journal of biochemical and molecular toxicology.

[118]  Yong Wang,et al.  EIF4A3-induced circARHGAP29 promotes aerobic glycolysis in docetaxel-resistant prostate cancer through IGF2BP2/c-Myc/LDHA signaling. , 2021, Cancer research.

[119]  W. Xia,et al.  METTL3 Is Suppressed by Circular RNA circMETTL3/miR-34c-3p Signaling and Limits the Tumor Growth and Metastasis in Triple Negative Breast Cancer , 2021, Frontiers in Oncology.

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[121]  Jiyao Sheng,et al.  m6A Modification-Mediated DUXAP8 Regulation of Malignant Phenotype and Chemotherapy Resistance of Hepatocellular Carcinoma Through miR-584-5p/MAPK1/ERK Pathway Axis , 2021, Frontiers in Cell and Developmental Biology.

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[132]  Juan Wang,et al.  Comprehensive Pan-Cancer Analysis of the Prognostic and Immunological Roles of the METTL3/lncRNA-SNHG1/miRNA-140-3p/UBE2C Axis , 2021, Frontiers in Cell and Developmental Biology.

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[134]  Zhengming Zhu,et al.  Construction of an N6-methyladenosine lncRNA- and immune cell infiltration-related prognostic model in colorectal cancer , 2021, Protoplasma.

[135]  Yidong Fan,et al.  FTO promotes tumour proliferation in bladder cancer via the FTO/miR-576/CDK6 axis in an m6A-dependent manner , 2021, Cell death discovery.

[136]  Yuan Zhang,et al.  Long non-coding RNAs: Biogenesis, functions, and clinical significance in gastric cancer , 2021, Molecular therapy oncolytics.

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[138]  Yun-long Pan,et al.  Comprehensive Analysis of N6-Methyladenosine-Related lncRNA Signature for Predicting Prognosis and Immune Cell Infiltration in Patients with Colorectal Cancer , 2021, Disease markers.

[139]  Chao Huang,et al.  Circ0008399 Interaction with WTAP Promotes Assembly and Activity of the m6A Methyltransferase Complex and Promotes Cisplatin Resistance in Bladder Cancer , 2021, Cancer Research.

[140]  Xuanfu Xu,et al.  M6A-mediated up-regulation of LncRNA LIFR-AS1 enhances the progression of pancreatic cancer via miRNA-150-5p/ VEGFA/Akt signaling , 2021, Cell cycle.

[141]  Tie Liu,et al.  A positive feedback loop of lncRNA-RMRP/ZNRF3 axis and Wnt/β-catenin signaling regulates the progression and temozolomide resistance in glioma , 2021, Cell Death & Disease.

[142]  Yuan Lin,et al.  M6A RNA methylation-mediated RMRP stability renders proliferation and progression of non-small cell lung cancer through regulating TGFBR1/SMAD2/SMAD3 pathway , 2021, Cell Death & Differentiation.

[143]  Ran Ma,et al.  lncRNA THAP7-AS1, transcriptionally activated by SP1 and post-transcriptionally stabilized by METTL3-mediated m6A modification, exerts oncogenic properties by improving CUL4B entry into the nucleus , 2021, Cell Death & Differentiation.

[144]  Shugeng Gao,et al.  Comprehensive Analysis of Clinical Significance, Immune Infiltration and Biological Role of m6A Regulators in Early-Stage Lung Adenocarcinoma , 2021, Frontiers in Immunology.

[145]  E. Zhao,et al.  Long Non-Coding RNA NRON promotes Tumor Proliferation by regulating ALKBH5 and Nanog in Gastric Cancer , 2021, Journal of Cancer.

[146]  Xi-lin Zhang,et al.  Crosstalk between N6-methyladenosine modification and circular RNAs: current understanding and future directions , 2021, Molecular cancer.

[147]  Sanyuan Hu,et al.  Identification of N6-Methyladenosine-Associated Long Non-coding RNAs for Immunotherapeutic Response and Prognosis in Patients With Pancreatic Cancer , 2021, Frontiers in Cell and Developmental Biology.

[148]  Jianquan Hou,et al.  METTL3-mediated m6A modification of KIF3C-mRNA promotes prostate cancer progression and is negatively regulated by miR-320d , 2021, Aging.

[149]  Xuehao Wang,et al.  m6A modification of circHPS5 and hepatocellular carcinoma progression through HMGA2 expression , 2021, Molecular therapy. Nucleic acids.

[150]  Yuqin Qiu,et al.  Integrated analysis on the N6‐methyladenosine‐related long noncoding RNAs prognostic signature, immune checkpoints, and immune cell infiltration in clear cell renal cell carcinoma , 2021, Immunity, inflammation and disease.

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