Biological and cytoselective anticancer properties of copper(II)-polypyridyl complexes modulated by auxiliary methylated glycine ligand

[1]  H. Seligmann,et al.  DNA Replication - Current Advances , 2011 .

[2]  N. Tsavaris,et al.  Topoisomerase I and II Expression in Recurrent Colorectal Cancer Cells: A Dubious Matter , 2011 .

[3]  R. Rodriguez,et al.  G-quadruplexes: selective DNA targeting for cancer therapeutics? , 2011, Expert review of clinical pharmacology.

[4]  Shashank K Singh,et al.  A propionyloxy derivative of 11-keto-β-boswellic acid induces apoptosis in HL-60 cells mediated through topoisomerase I & II inhibition. , 2011, Chemico-biological interactions.

[5]  J. Gan,et al.  Chemical and structural biology of nucleic acids and protein-nucleic acid complexes for novel drug discovery , 2011 .

[6]  F. Arjmand,et al.  Design and synthesis of heterobimetallic topoisomerase I and II inhibitor complexes: in vitro DNA binding, interaction with 5'-GMP and 5'-TMP and cleavage studies. , 2010, Journal of photochemistry and photobiology. B, Biology.

[7]  Cunyuan Zhao,et al.  Trinuclear Ru(II) polypyridyl complexes as human telomeric quadruplex DNA stabilizers , 2010 .

[8]  Bochu Wang,et al.  From GC-rich DNA binding to the repression of survivin gene for quercetin nickel (II) complex: implications for cancer therapy , 2010, BioMetals.

[9]  Stephen Neidle,et al.  Human telomeric G‐quadruplex: The current status of telomeric G‐quadruplexes as therapeutic targets in human cancer , 2010, The FEBS journal.

[10]  E. Zangrando,et al.  Copper(II) α-hydroxycarboxylate complexes of bis(2-pyridylcarbonyl)amine ligand: From mononuclear complex to one-dimensional coordination polymer , 2010 .

[11]  S. Ng,,et al.  Crystal structure, DNA binding studies, nucleolytic property and topoisomerase I inhibition of zinc complex with 1,10-phenanthroline and 3-methyl-picolinic acid , 2010, BioMetals.

[12]  Ying Sun,et al.  Tumor cellular proteasome inhibition and growth suppression by 8-hydroxyquinoline and clioquinol requires their capabilities to bind copper and transport copper into cells , 2010, JBIC Journal of Biological Inorganic Chemistry.

[13]  W. Ouellette,et al.  Pyrophosphate-bridged complexes with picomolar toxicity. , 2009, Journal of inorganic biochemistry.

[14]  S. Ito,et al.  Synthesis and biological activities of topoisomerase I inhibitors, 6-arylmethylamino analogues of edotecarin. , 2009, Journal of medicinal chemistry.

[15]  P. Tam,et al.  Gold(III) porphyrin complex is more potent than cisplatin in inhibiting growth of nasopharyngeal carcinoma in vitro and in vivo , 2009, International journal of cancer.

[16]  M. R. Webb,et al.  Anthocyanin Interactions with DNA: Intercalation, Topoisomerase I Inhibition and Oxidative Reactions. , 2008, Journal of food biochemistry.

[17]  F. Zunino,et al.  Targeting topoisomerase I: molecular mechanisms and cellular determinants of response to topoisomerase I inhibitors , 2008 .

[18]  Jian-liang Zhou,et al.  Ternary copper(II) complex of 1,10-phenanthroline and L-glycine: crystal structure and interaction with DNA , 2008 .

[19]  N. Smargiasso,et al.  Ligands playing musical chairs with G-quadruplex DNA: a rapid and simple displacement assay for identifying selective G-quadruplex binders. , 2008, Biochimie.

[20]  S. Ng,,et al.  Chlorido(2-methyl-4-oxo-4H-pyran-3-olato-κ 2 O 3,O 4)(1,10-phenanthroline-κ 2 N,N′)copper(II) , 2008, Acta Crystallographica Section E.

[21]  F. Gao,et al.  Synthesis, GC selective DNA binding and topoisomerase II inhibition activities of ruthenium(II) polypyridyl complex containing 11-aminopteridino[6,7-f][1,10]phenanthrolin-13(12H)-one. , 2008, Journal of inorganic biochemistry.

[22]  M. Chikira.  DNA-fiber EPR spectroscopy as a tool to study DNA-metal complex interactions: DNA binding of hydrated Cu(II) ions and Cu(II) complexes of amino acids and peptides. , 2008, Journal of inorganic biochemistry.

[23]  V. S. Periasamy,et al.  Non-covalent DNA binding and cytotoxicity of certain mixed-ligand ruthenium(II) complexes of 2,2'-dipyridylamine and diimines. , 2008, Dalton transactions.

[24]  B. Teicher.  Next generation topoisomerase I inhibitors: Rationale and biomarker strategies. , 2008, Biochemical pharmacology.

[25]  N. Hanna.  Open-Label, Uncontrolled, Multicenter Phase II Study to Evaluate the Efficacy and Toxicity of Cetuximab As a Single Agent in Patients With Recurrent and/or Metastatic Squamous Cell Carcinoma of the Head and Neck Who Failed to Respond to Platinum-Based Therapy , 2008 .

[26]  G. Sheldrick.  A short history of SHELX. , 2008, Acta crystallographica. Section A, Foundations of crystallography.

[27]  D. S. Pandey,et al.  DNA binding and topoisomerase II inhibitory activity of water-soluble ruthenium(II) and rhodium(III) complexes. , 2007, Inorganic chemistry.

[28]  J. Barton,et al.  Metallo-intercalators and metallo-insertors. , 2007, Chemical communications.

[29]  Y. Pommier,et al.  Batracylin (NSC 320846), a dual inhibitor of DNA topoisomerases I and II induces histone gamma-H2AX as a biomarker of DNA damage. , 2007, Cancer research.

[30]  S. Ramakumar,et al.  Metal-based netropsin mimics showing AT-selective DNA binding and DNA cleavage activity at red light. , 2007, Inorganic chemistry.

[31]  X. Hua,et al.  Targeting ROS: Selective killing of cancer cells by a cruciferous vegetable derived pro-oxidant compound , 2007, Cancer Biology & Therapy.

[32]  M. Liu-González,et al.  Synthesis, structure, and nuclease properties of several binary and ternary complexes of copper(II) with norfloxacin and 1,10 phenantroline. , 2007, Journal of inorganic biochemistry.

[33]  M. Krishnaveni,et al.  Synthesis, characterization and in vitro biological activity studies of Cu-M (M = Cu2+, Co2+, Ni2+, Mn2+, Zn2+) bimetallic complexes. , 2006, European journal of medicinal chemistry.

[34]  Balachandran Unni Nair,et al.  Unprecedented dual binding behaviour of acridine group of dye: a combined experimental and theoretical investigation for the development of anticancer chemotherapeutic agents. , 2006, Biochimica et biophysica acta.

[35]  O. Yamauchi,et al.  DNA-binding properties of flexible diamine bridged dinuclear ruthenium(II)-2,2′-bipyridine complexes , 2006 .

[36]  Y. Pommier.  Topoisomerase I inhibitors: camptothecins and beyond , 2006, Nature Reviews Cancer.

[37]  C. Bailly,et al.  Exploring the Cellular Activity of Camptothecin-Triple-Helix-Forming Oligonucleotide Conjugates , 2006, Molecular and Cellular Biology.

[38]  I. Kostova.  Platinum complexes as anticancer agents. , 2006, Recent patents on anti-cancer drug discovery.

[39]  Qing‐Yu He,et al.  Proteomic characterization of the cytotoxic mechanism of gold (III) porphyrin 1a, a potential anticancer drug , 2006, Proteomics.

[40]  K. McMasters,et al.  SW-620 cells treated with topoisomerase I inhibitor SN-38: gene expression profiling , 2005, Journal of Translational Medicine.

[41]  Pin Yang,et al.  Racemic D,L-[Co(phen)2dpq](3+)-DNA interactions: investigation into the basis for minor-groove binding and recognition. , 2005, Journal of inorganic biochemistry.

[42]  T. Poon,et al.  Antitumor effect and enhancement of cytotoxic drug activity by cetuximab in nasopharyngeal carcinoma cells. , 2005, In vivo.

[43]  J. Adams.  The proteasome: a suitable antineoplastic target , 2004, Nature Reviews Cancer.

[44]  W. Guida,et al.  Organic copper complexes as a new class of proteasome inhibitors and apoptosis inducers in human cancer cells. , 2004, Biochemical pharmacology.

[45]  N. Nagesh,et al.  A comparative study on the interaction of acridine and synthetic bis-acridine with G-quadruplex structure. , 2003, Journal of biochemical and biophysical methods.

[46]  W. Antholine,et al.  DNA-fiber EPR study of the orientation of Cu(II) complexes of 1,10-phenanthroline and its derivatives bound to DNA: mono(phenanthroline)-copper(II) and its ternary complexes with amino acids. , 2002, Journal of inorganic biochemistry.

[47]  S. Khalid,et al.  Intramolecular DNA coiling mediated by metallo-supramolecular cylinders: Differential binding of P and M helical enantiomers , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[48]  D. Boger,et al.  A simple, high-resolution method for establishing DNA binding affinity and sequence selectivity. , 2001, Journal of the American Chemical Society.

[49]  R. Sheardy,et al.  Locating cobalt-binding sites on DNA using restriction endonucleases. , 2001, Methods in enzymology.

[50]  T. Koike,et al.  Selective recognition of consecutive G sequence in double-stranded DNA by a zinc(II)-macrocyclic tetraamine complex appended with an anthraquinone. , 2000, Journal of inorganic biochemistry.

[51]  A. Casini,et al.  DNA as a possible target for antitumor ruthenium(III) complexes. , 2000, Archives of biochemistry and biophysics.

[52]  J. Collins,et al.  A 1H NMR study of the oligonucleotide binding of [(en)Pt(mu-dpzm)2Pt(en)]Cl4. , 2000, Journal of inorganic biochemistry.

[53]  D. Odom,et al.  Recognition and reaction of metallointercalators with DNA. , 1999, Chemical reviews.

[54]  S. Hecht,et al.  Differential effects of camptothecin derivatives on topoisomerase I-mediated DNA structure modification. , 1998, Biochemistry.

[55]  F. Zunino,et al.  A protein-mediated mechanism for the DNA sequence-specific action of topoisomerase II poisons. , 1997, Trends in pharmacological sciences.

[56]  M. Rothenberg.  Topoisomerase I inhibitors: review and update. , 1997, Annals of oncology : official journal of the European Society for Medical Oncology.

[57]  H. Shindo,et al.  How amino acids control the binding of Cu(II) ions to DNA (II): effect of basic amino acid residues and the chirality on the orientation of the complexes. , 1997, Journal of inorganic biochemistry.

[58]  C. Loup,et al.  Influence of the nature of the porphyrin ligand on the nuclease activity of metalloporphyrin-oligonucleotide conjugates designed with cationic, hydrophobic or anionic metalloporphyrins. , 1997, Nucleic acids research.

[59]  J. Collins,et al.  NMR Evidence for Sequence-Specific DNA Minor Groove Binding by Bis(ethylenediamine)platinum(II) , 1996 .

[60]  G. Will,et al.  Synthesis and characterisation of Cu(II) complexes with the 2-acetamido-N-(4-methyl-2-thiazolyl) (amtz) ligand. The crystal structure of [Cu(amtz)2H2O](NO3)2 , 1996 .

[61]  C. Lin,et al.  Modification of DNA topoisomerase I enzymatic activity with phosphotyrosyl protein phosphatase and alkaline phosphatase from the hepatopancreas of the shrimp Penaeus japonicus (Crustacea:Decapoda). , 1996, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.

[62]  J. Barton,et al.  Sequence-specific recognition of DNA by phenanthrenequinone diimine complexes of rhodium(III): importance of steric and van der Waals interactions. , 1994, Biochemistry.

[63]  B. Nordén,et al.  Binding of delta- and lambda-[Ru(phen)3]2+ to [d(CGCGATCGCG)]2 studied by NMR. , 1994, Biochemistry.

[64]  J. Barton,et al.  Enantiospecific palindromic recognition of 5'-d(CTCTAGAG)-3' by a novel rhodium intercalator: analogies to a DNA-binding protein , 1993 .

[65]  J. Barton,et al.  DNA recognition by rhodium(III) polyamine intercalators: Considerations of hydrogen bonding and van der Waals interactions , 1993 .

[66]  J. Francois,et al.  Sequence-targeted cleavage of single- and double-stranded DNA by oligothymidylates covalently linked to 1,10-phenanthroline. , 1989, The Journal of biological chemistry.

[67]  D. Sigman,et al.  Nuclease activity of 1,10-phenanthroline-copper: sequence-specific targeting. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[68]  S. Rice,et al.  A Further Examination of the Molecular Weight and Size of Desoxypentose Nucleic Acid , 1954 .