Efficacy and safety of single-agent pertuzumab (rhuMAb 2C4), a human epidermal growth factor receptor dimerization inhibitor, in castration-resistant prostate cancer after progression from taxane-based therapy.
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David S Mendelson | M. Morris | H. Scher | M. Kattan | D. McNeel | D. Agus | C. Sweeney | M. Derynck | D. Allison | K. Ng | David B Agus | Howard I Scher | Michael J Morris | Michael W Kattan | D. Mendelson | Christopher J Sweeney | Kimmie Ng | Douglas G McNeel | Frederick R Ahmann | Jin Wang | Mika K Derynck | Benjamin Lyons | David E Allison | F. Ahmann | B. Lyons | Jin Wang
[1] L. Sokoll,et al. Dissociation between androgen responsiveness for malignant growth vs. expression of prostate specific differentiation markers PSA, hK2, and PSMA in human prostate cancer models , 2003, The Prostate.
[2] M. Sliwkowski,et al. Dose-response studies of recombinant humanized monoclonal antibody 2C4 in tumor xenograft models , 2003 .
[3] R. Simon,et al. Optimal two-stage designs for phase II clinical trials. , 1989, Controlled clinical trials.
[4] B. Karlan,et al. Phase I clinical study of pertuzumab, a novel HER dimerization inhibitor, in patients with advanced cancer. , 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[5] J. Manola,et al. Response to second-line chemotherapy in patients with hormone refractory prostate cancer receiving two sequences of mitoxantrone and taxanes. , 2006, Urology.
[6] B. Freidlin,et al. Eligibility and response guidelines for phase II clinical trials in androgen-independent prostate cancer: recommendations from the Prostate-Specific Antigen Working Group. , 1999, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[7] M. Sliwkowski. Ready to partner , 2003, Nature Structural Biology.
[8] C. Cordon-Cardo,et al. Changing pattern of expression of the epidermal growth factor receptor and transforming growth factor alpha in the progression of prostatic neoplasms. , 1995, Clinical cancer research : an official journal of the American Association for Cancer Research.
[9] M. Kraus,et al. Cooperative signaling of ErbB3 and ErbB2 in neoplastic transformation and human mammary carcinomas. , 1995, Oncogene.
[10] M. Sliwkowski,et al. Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex. , 2004, Cancer cell.
[11] C. Kollmannsberger,et al. First‐ and second‐line chemotherapy with docetaxel or mitoxantrone in patients with hormone‐refractory prostate cancer , 2006, Cancer.
[12] S. Groshen,et al. Her-2/neu expression in prostate cancer: high level of expression associated with exposure to hormone therapy and androgen independent disease. , 2001, The Journal of urology.
[13] C. Cordon-Cardo,et al. HER-2/neu (p185neu) protein expression in the natural or treated history of prostate cancer. , 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.
[14] C. Parker,et al. An open label, phase II, multicenter, study to evaluate the efficacy and safety of pertuzumab (P) in chemotherapy naïve patients (pts) with hormone refractory prostate cancer (HRPC) , 2005 .
[15] V. Reuter,et al. HER‐2 profiling and targeting in prostate carcinoma , 2002, Cancer.
[16] A. Ullrich,et al. Heregulin‐dependent regulation of HER2/neu oncogenic signaling by heterodimerization with HER3. , 1995, The EMBO journal.
[17] Y. Yarden,et al. Diversification of Neu differentiation factor and epidermal growth factor signaling by combinatorial receptor interactions. , 1996, The EMBO journal.
[18] R. Brant,et al. Comparison of 2 methods for calculating adjusted survival curves from proportional hazards models. , 2001, JAMA.
[19] C. Kollmannsberger,et al. First- and second-line chemotherapy with docetaxel or mitoxantrone in patients with hormone-refractory prostate cancer (HRPC): Does sequence matter? , 2005 .
[20] F. S. French,et al. Heregulin-Induced Activation of HER2 and HER3 Increases Androgen Receptor Transactivation and CWR-R1 Human Recurrent Prostate Cancer Cell Growth , 2005, Clinical Cancer Research.
[21] M. van Glabbeke,et al. New guidelines to evaluate the response to treatment in solid tumors , 2000, Journal of the National Cancer Institute.
[22] W. Gerald,et al. Targeting the androgen receptor: improving outcomes for castration-resistant prostate cancer. , 2004, Endocrine-related cancer.
[23] H. Scher,et al. Second-line chemotherapy for prostate cancer: patient characteristics and survival. , 2005, Clinical prostate cancer.
[24] G. Stamp,et al. Phosphorylation of both EGFR and ErbB2 is a reliable predictor of prostate cancer cell proliferation in response to EGF. , 2004, Neoplasia.
[25] I. Mellinghoff,et al. Growth inhibitory effects of the dual ErbB1/ErbB2 tyrosine kinase inhibitor PKI-166 on human prostate cancer xenografts. , 2002, Cancer research.
[26] Ingo K Mellinghoff,et al. HER2/neu kinase-dependent modulation of androgen receptor function through effects on DNA binding and stability. , 2004, Cancer cell.
[27] L. Schwartz,et al. Prostate Cancer Clinical Trial End Points: “RECIST”ing a Step Backwards , 2005, Clinical Cancer Research.
[28] Kuo-Fen Lee,et al. Essential roles of Her2/erbB2 in cardiac development and function. , 2004, Recent progress in hormone research.
[29] H. Ito,et al. Androgen receptor involvement in the progression of prostate cancer. , 2003, Endocrine-related cancer.
[30] I. Tannock,et al. Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer. , 2004, The New England journal of medicine.
[31] Brian Higgins,et al. Targeting ligand-activated ErbB2 signaling inhibits breast and prostate tumor growth. , 2002, Cancer cell.
[32] Y. Yarden,et al. Untangling the ErbB signalling network , 2001, Nature Reviews Molecular Cell Biology.
[33] N. Hynes,et al. The ErbB receptors and their role in cancer progression. , 2003, Experimental cell research.
[34] J. Manola,et al. Her-2-neu expression and progression toward androgen independence in human prostate cancer. , 2000, Journal of the National Cancer Institute.
[35] Noah Craft,et al. A mechanism for hormone-independent prostate cancer through modulation of androgen receptor signaling by the HER-2/neu tyrosine kinase , 1999, Nature Medicine.
[36] G. Blackledge. Growth factor receptor tyrosine kinase inhibitors; clinical development and potential for prostate cancer therapy. , 2003, The Journal of urology.
[37] M. Sliwkowski,et al. An open-and-shut case? Recent insights into the activation of EGF/ErbB receptors. , 2003, Molecular cell.
[38] C. Tangen,et al. Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer. , 2004, The New England journal of medicine.
[39] Kevin Regan,et al. Nomogram for overall survival of patients with progressive metastatic prostate cancer after castration. , 2002, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.