Brain-Specific Phosphorylation of MeCP2 Regulates Activity-Dependent Bdnf Transcription, Dendritic Growth, and Spine Maturation

[1]  T. Soderling,et al.  Activity-Dependent Dendritic Arborization Mediated by CaM-Kinase I Activation and Enhanced CREB-Dependent Transcription of Wnt-2 , 2006, Neuron.

[2]  H. Zoghbi,et al.  MeCP2 dysfunction in Rett syndrome and related disorders. , 2006, Current opinion in genetics & development.

[3]  E. Kavalali,et al.  MeCP2-Dependent Transcriptional Repression Regulates Excitatory Neurotransmission , 2006, Current Biology.

[4]  P. Tam,et al.  Mecp2 deficiency is associated with learning and cognitive deficits and altered gene activity in the hippocampal region of mice. , 2006, Brain : a journal of neurology.

[5]  S. Nelson,et al.  The Disease Progression of Mecp2 Mutant Mice Is Affected by the Level of BDNF Expression , 2006, Neuron.

[6]  A. Bird,et al.  Genomic DNA methylation: the mark and its mediators. , 2006, Trends in biochemical sciences.

[7]  James H. Eubanks,et al.  Hippocampal synaptic plasticity is impaired in the Mecp2-null mouse model of Rett syndrome , 2006, Neurobiology of Disease.

[8]  H. Zoghbi,et al.  Learning and Memory and Synaptic Plasticity Are Impaired in a Mouse Model of Rett Syndrome , 2006, The Journal of Neuroscience.

[9]  B. D. de Vries,et al.  Chromosomal copy number changes in patients with non-syndromic X linked mental retardation detected by array CGH , 2005, Journal of Medical Genetics.

[10]  J. Gécz,et al.  Duplication of the MECP2 region is a frequent cause of severe mental retardation and progressive neurological symptoms in males. , 2005, American journal of human genetics.

[11]  Rudolf Jaenisch,et al.  Reduced cortical activity due to a shift in the balance between excitation and inhibition in a mouse model of Rett syndrome. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[12]  G. Mandel,et al.  REST and Its Corepressors Mediate Plasticity of Neuronal Gene Chromatin throughout Neurogenesis , 2005, Cell.

[13]  M. Greenberg,et al.  Transcriptional control of cognitive development , 2005, Current Opinion in Neurobiology.

[14]  K. Hameister,et al.  Submicroscopic duplication in Xq28 causes increased expression of the MECP2 gene in a boy with severe mental retardation and features of Rett syndrome , 2005, Journal of Medical Genetics.

[15]  H. Zoghbi,et al.  Abnormalities of social interactions and home-cage behavior in a mouse model of Rett syndrome. , 2005, Human molecular genetics.

[16]  Noriyuki Kishi,et al.  MECP2 is progressively expressed in post-migratory neurons and is involved in neuronal maturation rather than cell fate decisions , 2004, Molecular and Cellular Neuroscience.

[17]  H. Zoghbi,et al.  Mild overexpression of MeCP2 causes a progressive neurological disorder in mice. , 2004, Human molecular genetics.

[18]  R. Rocchi,et al.  Real‐time quantitative PCR as a routine method for screening large rearrangements in Rett syndrome: Report of one case of MECP2 deletion and one case of MECP2 duplication , 2004, Human mutation.

[19]  T. Soderling,et al.  Calcium Activation of ERK Mediated by Calmodulin Kinase I* , 2004, Journal of Biological Chemistry.

[20]  R. Jaenisch,et al.  Expression of MeCP2 in postmitotic neurons rescues Rett syndrome in mice. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[21]  T. Soderling,et al.  Regulation of Axonal Extension and Growth Cone Motility by Calmodulin-Dependent Protein Kinase I , 2004, The Journal of Neuroscience.

[22]  Azad Bonni,et al.  A CaMKII-NeuroD Signaling Pathway Specifies Dendritic Morphogenesis , 2004, Neuron.

[23]  H. Zoghbi Postnatal Neurodevelopmental Disorders: Meeting at the Synapse? , 2003, Science.

[24]  Daisuke Hattori,et al.  DNA Methylation-Related Chromatin Remodeling in Activity-Dependent Bdnf Gene Regulation , 2003, Science.

[25]  Eric C. Griffith,et al.  Derepression of BDNF Transcription Involves Calcium-Dependent Phosphorylation of MeCP2 , 2003, Science.

[26]  A. Bird,et al.  DNA methylation and Rett syndrome. , 2003, Human molecular genetics.

[27]  Eric C. Griffith,et al.  Regulation of transcription factors by neuronal activity , 2002, Nature Reviews Neuroscience.

[28]  Juan I. Young,et al.  Mice with Truncated MeCP2 Recapitulate Many Rett Syndrome Features and Display Hyperacetylation of Histone H3 , 2002, Neuron.

[29]  Anirvan Ghosh,et al.  Calcium Regulation of Dendritic Growth via CaM Kinase IV and CREB-Mediated Transcription , 2002, Neuron.

[30]  H. Bading,et al.  Extrasynaptic NMDARs oppose synaptic NMDARs by triggering CREB shut-off and cell death pathways , 2002, Nature Neuroscience.

[31]  Eric C. Griffith,et al.  CREB Transcriptional Activity in Neurons Is Regulated by Multiple, Calcium-Specific Phosphorylation Events , 2002, Neuron.

[32]  J. Lisman,et al.  The molecular basis of CaMKII function in synaptic and behavioural memory , 2002, Nature Reviews Neuroscience.

[33]  David Baltimore,et al.  Germline Transmission and Tissue-Specific Expression of Transgenes Delivered by Lentiviral Vectors , 2002, Science.

[34]  R. Jaenisch,et al.  Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice , 2001, Nature Genetics.

[35]  B. Lom,et al.  Brain-Derived Neurotrophic Factor Differentially Regulates Retinal Ganglion Cell Dendritic and Axonal Arborization In Vivo , 1999, The Journal of Neuroscience.

[36]  H. Zoghbi,et al.  Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2 , 1999, Nature Genetics.

[37]  A. Wolffe,et al.  The methyl-CpG binding transcriptional repressor MeCP2 stably associates with nucleosomal DNA. , 1999, Biochemistry.

[38]  M. Greenberg,et al.  Akt Promotes Cell Survival by Phosphorylating and Inhibiting a Forkhead Transcription Factor , 1999, Cell.

[39]  T. Soderling,et al.  Characterization of a calmodulin kinase II inhibitor protein in brain. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[40]  Tobias Meyer,et al.  CaMKIIβ Functions As an F-Actin Targeting Module that Localizes CaMKIIα/β Heterooligomers to Dendritic Spines , 1998, Neuron.

[41]  P. Worley,et al.  Immediate-Early Genes and Synaptic Function , 1998, Neurobiology of Learning and Memory.

[42]  C. Shatz,et al.  Synaptic Activity and the Construction of Cortical Circuits , 1996, Science.

[43]  M. Greenberg,et al.  Calcium Influx via the NMDA Receptor Induces Immediate Early Gene Transcription by a MAP Kinase/ERK-Dependent Mechanism , 1996, The Journal of Neuroscience.

[44]  Ted Abel,et al.  Recombinant BDNF Rescues Deficits in Basal Synaptic Transmission and Hippocampal LTP in BDNF Knockout Mice , 1996, Neuron.

[45]  J. Kornhauser,et al.  Light, immediate-early genes, and circadian rhythms , 1996, Behavior genetics.

[46]  Lawrence C. Katz,et al.  Neurotrophins regulate dendritic growth in developing visual cortex , 1995, Neuron.

[47]  T Bonhoeffer,et al.  Hippocampal long-term potentiation is impaired in mice lacking brain-derived neurotrophic factor. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[48]  H. Enslen,et al.  Differential activation of CREB by Ca2+/calmodulin-dependent protein kinases type II and type IV involves phosphorylation of a site that negatively regulates activity. , 1994, Genes & development.

[49]  A. Bird,et al.  Purification, sequence, and cellular localization of a novel chromosomal protein that binds to Methylated DNA , 1992, Cell.

[50]  D. Muller,et al.  A simple method for organotypic cultures of nervous tissue , 1991, Journal of Neuroscience Methods.

[51]  Jean Aicardi,et al.  A progressive syndrome of autism, dementia, ataxia, and loss of purposeful hand use in girls: Rett's syndrome: Report of 35 cases , 1983, Annals of neurology.

[52]  A Rett,et al.  [On a unusual brain atrophy syndrome in hyperammonemia in childhood]. , 1966, Wiener medizinische Wochenschrift.

[53]  J. Chelly,et al.  Molecular genetics of Rett syndrome: when DNA methylation goes unrecognized , 2006, Nature Reviews Genetics.

[54]  K. Svoboda,et al.  Structure and function of dendritic spines. , 2002, Annual review of physiology.

[55]  S. Reppert,et al.  Molecular analysis of mammalian circadian rhythms. , 2001, Annual review of physiology.

[56]  A. Bird,et al.  A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome , 2001, Nature Genetics.

[57]  Mu-ming Poo,et al.  Neurotrophins as synaptic modulators , 2001, Nature Reviews Neuroscience.

[58]  S. Zeiler,et al.  Development/Plasticity/Repair Brain-Derived Neurotrophic Factor Is Required for the Maintenance of Cortical Dendrites , 2022 .