Reduction of intracellular pH by tenidap. Involvement of cellular anion transporters in the pH change.

[1]  C. Gabel,et al.  Inhibition of cytokine activation processes in vitro by tenidap, a novel anti-inflammatory agent. , 1995, Cytokine.

[2]  C. Gabel,et al.  Tenidap modulates cytoplasmic pH and inhibits anion transport in vitro. II. Inhibition of IL-1 beta production from ATP-treated monocytes and macrophages. , 1994, Journal of immunology.

[3]  C. Gabel,et al.  Tenidap modulates cytoplasmic pH and inhibits anion transport in vitro. I. Mechanism and evidence of functional significance. , 1994, Journal of immunology.

[4]  A. Garnier-Suillerot,et al.  Mobile ionophores are a novel class of P-glycoprotein inhibitors. The effects of ionophores on 4'-O-tetrahydropyranyl-adriamycin incorporation in K562 drug-resistant cells. , 1994, European journal of biochemistry.

[5]  R. Hogg,et al.  Action of niflumic acid on evoked and spontaneous calcium‐activated chloride and potassium currents in smooth muscle cells from rabbit portal vein , 1994, British journal of pharmacology.

[6]  C. Gabel,et al.  Interleukin-1 beta maturation and release in response to ATP and nigericin. Evidence that potassium depletion mediated by these agents is a necessary and common feature of their activity. , 1994, The Journal of biological chemistry.

[7]  P. Gros,et al.  Structurally distinct MDR modulators show specific patterns of reversal against P-glycoproteins bearing unique mutations at serine939/941. , 1994, Biochemistry.

[8]  K. Ullrich.  Specificity of transporters for 'organic anions' and 'organic cations' in the kidney. , 1994, Biochimica et biophysica acta.

[9]  S. Simon,et al.  Intracellular pH and the control of multidrug resistance. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[10]  J. Martel-Pelletier,et al.  Regulation of human normal and osteoarthritic chondrocyte interleukin-1 receptor by antirheumatic drugs. , 1993, Arthritis and rheumatism.

[11]  T. Hughes,et al.  Altered expression of unidirectional extrusion routes for methotrexate and cholate in an efflux variant of L1210 cells. , 1993, Biochimica et biophysica acta.

[12]  S. Reddy,et al.  Expression of the protein product of the prostaglandin synthase-2/TIS10 gene in mitogen-stimulated Swiss 3T3 cells. , 1993, The Journal of biological chemistry.

[13]  R. Fox,et al.  Mechanism of Action of Antimalarial Drugs: Inhibition of Antigen Processing and Presentation , 1993, Lupus.

[14]  R. Greger,et al.  Chemical probes for anion transporters of mammalian cell membranes. , 1992, The American journal of physiology.

[15]  R. Ward,et al.  Measurement of human phospholipase A2 in arthritis plasma using a newly developed sandwich ELISA. , 1992, British journal of rheumatology.

[16]  J. Sipe,et al.  Modification of proinflammatory cytokine production by the antirheumatic agents tenidap and naproxen. A possible correlate with clinical acute phase response. , 1992, Journal of immunology.

[17]  I. Otterness,et al.  Inhibition of interleukin 1 synthesis by tenidap: a new drug for arthritis. , 1991, Cytokine.

[18]  L. Simchowitz,et al.  Intracellular pH recovery from alkalinization. Characterization of chloride and bicarbonate transport by the anion exchange system of human neutrophils , 1990, The Journal of general physiology.

[19]  E. Simons,et al.  Neutrophil hyperpolarization in response to a chemotactic peptide. , 1990, The Journal of biological chemistry.

[20]  I. Pastan,et al.  Activity of the multidrug transporter results in alkalinization of the cytosol: measurement of cytosolic pH by microinjection of a pH-sensitive dye. , 1990, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[21]  J. Howbert,et al.  Studies on the cellular pharmacology of N-(4-methylphenylsulfonyl)-N'-(4-chlorophenyl)-urea. , 1990, Biochemical pharmacology.

[22]  J. Howbert,et al.  Evidence for mitochondrial localization of N-(4-methylphenylsulfonyl)-N'-(4-chlorophenyl)urea in human colon adenocarcinoma cells. , 1990, Cancer research.

[23]  A. Whetton,et al.  Granulocyte-macrophage colony-stimulating factor can stimulate macrophage proliferation via persistent activation of Na+/H+ antiport. Evidence for two distinct roles for Na+/H+ antiport activation. , 1990, The Biochemical journal.

[24]  M. Conklyn,et al.  Inhibition of IgE-mediated N-acetylglucosaminidase and serotonin release from rat basophilic leukemia cells (RBL-2H3) by tenidap: a novel anti-inflammatory agent. , 1990, International archives of allergy and applied immunology.

[25]  J. Endicott,et al.  The biochemistry of P-glycoprotein-mediated multidrug resistance. , 1989, Annual review of biochemistry.

[26]  H. Vapaatalo,et al.  CP-66,248, a new anti-inflammatory agent, is a potent inhibitor of leukotriene B4 and prostanoid synthesis in human polymorphonuclear leucocytes in vitro. , 1988, Eicosanoids.

[27]  J. Swanson,et al.  Macrophages possess probenecid-inhibitable organic anion transporters that remove fluorescent dyes from the cytoplasmic matrix , 1987, The Journal of cell biology.

[28]  M. Reitman,et al.  Epithelial chloride channel. Development of inhibitory ligands , 1987, The Journal of general physiology.

[29]  G. Henderson,et al.  Methotrexate efflux in L1210 cells. Kinetic and specificity properties of the efflux system sensitive to bromosulfophthalein and its possible identity with a system which mediates the efflux of 3',5'-cyclic AMP. , 1987, The Journal of biological chemistry.

[30]  S. Chan,et al.  Molecular mechanisms of band 3 inhibitors. 3. Translocation inhibitors. , 1986, Biochemistry.

[31]  E. Cragoe,et al.  Inhibition of chemotactic factor-activated Na+/H+ exchange in human neutrophils by analogues of amiloride: structure-activity relationships in the amiloride series. , 1986, Molecular pharmacology.

[32]  S. Grinstein,et al.  Characterization of the amiloride-sensitive Na+-H+ antiport of human neutrophils. , 1986, The American journal of physiology.

[33]  A. Roos,et al.  Regulation of intracellular pH in human neutrophils , 1985, The Journal of general physiology.

[34]  S. Grinstein,et al.  Amiloride-sensitive Na+/H+ exchange in human neutrophils: mechanism of activation by chemotactic factors. , 1984, Biochemical and biophysical research communications.

[35]  P. Aronson.  Mechanisms of active H+ secretion in the proximal tubule. , 1983, The American journal of physiology.

[36]  J. Cousin,et al.  Inhibition of anion transport in the red blood cell by anionic amphiphilic compounds. II. Chemical properties of the flufenamate-binding site on the band 3 protein. , 1982, Biochimica et biophysica acta.

[37]  A. Richman,et al.  Reciprocal relationship of synovial fluid volume and oxygen tension. , 1981, Arthritis and rheumatism.

[38]  W. S. Koski,et al.  Correlation between the growth inhibitory effects, partition coefficients and teratogenic effects of lipophilic acids. , 1979, Teratology.

[39]  K. Kohn,et al.  DNA-protein and DNA interstrand cross-linking by cis- and trans-platinum(II) diamminedichloride in L1210 mouse leukemia cells and relation to cytotoxicity. , 1979, Cancer research.

[40]  A. Ferrante,et al.  A rapid one-step procedure for purification of mononuclear and polymorphonuclear leukocytes from human blood using a modification of the Hypaque-Ficoll technique. , 1978, Journal of immunological methods.

[41]  B. Pressman,et al.  Biological applications of ionophores. , 1976, Annual review of biochemistry.

[42]  A. Halestrap.  The mitochondrial pyruvate carrier. Kinetics and specificity for substrates and inhibitors. , 1975, The Biochemical journal.