Selective minimum-norm solution of the biomagnetic inverse problem

A new multidipole estimation method which gives a sparse solution of the biomagnetic inverse problem is proposed. This solution is extracted from the basic feasible solutions of linearly independent data equations. These feasible solutions are obtained by selecting exactly as many dipole-moments as the number of magnetic sensors. By changing the selection, the authors search for the minimum-norm vector of selected moments. As a result, a practically sparse solution is obtained; computer-simulated solutions for L/sub p/-norm (p=2, 1, 0.5, 0.2) have a small number of significant moments around the real source-dipoles. In particular, the solution for L/sub 1/-norm is equivalent to the minimum-L/sub 1/-norm solution of the original inverse problem. This solution can be uniquely computed by using linear programming.<<ETX>>

[1]  Z. Cho,et al.  SVD pseudoinversion image reconstruction , 1981 .

[2]  W. Dallas Fourier space solution to the magnetostatic imaging problem. , 1985, Applied optics.

[3]  J. Sarvas Basic mathematical and electromagnetic concepts of the biomagnetic inverse problem. , 1987, Physics in medicine and biology.

[4]  William J. Dallas,et al.  Fourier Imaging of Electrical Currents in the Human Brain from Their Magnetic Fields , 1987, IEEE Transactions on Biomedical Engineering.

[5]  Manbir Singh,et al.  An Evaluation of Methods for Neuromagnetic Image Reconstruction , 1987, IEEE Transactions on Biomedical Engineering.

[6]  Direct Approach to an Inverse Problem: A Trial to Describe Signal Sources by Current Elements Distribution , 1989 .

[7]  N. G. Sepulveda,et al.  Using a magnetometer to image a two‐dimensional current distribution , 1989 .

[8]  W E Smith,et al.  Linear estimation theory applied to the reconstruction of a 3-D vector current distribution. , 1990, Applied optics.

[9]  Yoshifuru Saito,et al.  A formulation of the inverse problems in magnetostatic fields and its application to a source position searching of the human eye fields , 1990 .

[10]  R E Alvarez Biomagnetic Fourier imaging [current density reconstruction]. , 1990, IEEE transactions on medical imaging.

[11]  J.C. Mosher,et al.  Multiple dipole modeling and localization from spatio-temporal MEG data , 1992, IEEE Transactions on Biomedical Engineering.

[12]  Manbir Singh,et al.  Neuromagnetic localization using magnetic resonance images , 1992, IEEE Trans. Medical Imaging.

[13]  L. Kaufman,et al.  Magnetic source images determined by a lead-field analysis: the unique minimum-norm least-squares estimation , 1992, IEEE Transactions on Biomedical Engineering.

[14]  W.E. Smith Estimation of the spatio-temporal correlations of biological electrical sources from their magnetic fields , 1992, IEEE Transactions on Biomedical Engineering.

[15]  Hideaki Haneishi,et al.  Details of simulated annealing algorithm to estimate parameters of multiple current dipoles using biomagnetic data , 1992, IEEE Trans. Medical Imaging.