Enhanced release of plasminogen activator inhibitor(s) but not of plasminogen activators by cultured rat glial cells treated with interleukin‐1

Astroglial cells are known to proliferate during development of the nervous system, as well as during post‐traumatic gliosis. We have previously shown that the proliferation of cultured astrocytes can be stimulated by the urokinase‐type (uPA) of plasminogen activator (PA) and that astrocytes are able to release such uPA upon stimulation with basic fibroblast growth factor, which is known to act as a mitogen for these cells.

[1]  G. Moonen,et al.  A colorimetric assay for the simultaneous measurement of plasminogen activators and plasminogen activator inhibitors in serum-free conditioned media from cultured cells. , 1989, Analytical biochemistry.

[2]  A. Prochiantz,et al.  Brain macrophages synthesize interleukin‐1 and interleukin‐1 mRNAs in vitro , 1988, Journal of neuroscience research.

[3]  B. Pettmann,et al.  Brain basic fibroblast growth factor stimulates the release of plasminogen activators by newborn rat cultured astroglial cells , 1988, Neuroscience Letters.

[4]  M. Gimbrone,et al.  Cytokine activation of vascular endothelium. Effects on tissue-type plasminogen activator and type 1 plasminogen activator inhibitor. , 1988, The Journal of biological chemistry.

[5]  R. Nussenblatt,et al.  Glial retinal Müller cells produce IL-1 activity and have a dual effect on autoimmune T helper lymphocytes. Antigen presentation manifested after removal of suppressive activity. , 1988, Journal of immunology.

[6]  C. Dinarello,et al.  Biology of interleukin 1 , 1988, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[7]  D. Giulian,et al.  Interleukin-1 is an astroglial growth factor in the developing brain , 1988, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[8]  G. Moonen,et al.  Plasminogen activators in developing peripheral nervous system, cellular origin and mitogenic effect. , 1987, Brain research.

[9]  C. Cotman,et al.  Identification of a protease inhibitor produced by astrocytes that is structurally and functionally homologous to human protease nexin-I , 1987, Brain Research.

[10]  G. Moonen,et al.  Potassium-induced release of neuronotoxic activity by astrocytes , 1987, Brain Research.

[11]  C. Dinarello,et al.  Growth-promoting effect of recombinant interleukin 1 and tumor necrosis factor for a human astrocytoma cell line. , 1987, Journal of immunology.

[12]  R. Simpson,et al.  Identification of the human 26-kD protein, interferon beta 2 (IFN-beta 2), as a B cell hybridoma/plasmacytoma growth factor induced by interleukin 1 and tumor necrosis factor , 1987, The Journal of experimental medicine.

[13]  J. Vilček,et al.  Tumor necrosis factor and interleukin 1: cytokines with multiple overlapping biological activities. , 1987, Laboratory investigation; a journal of technical methods and pathology.

[14]  Willem,et al.  Interleukin-1 (22-K factor) induces release of granulocyte-macrophage colony-stimulating activity from human mononuclear phagocytes. , 1986, Blood.

[15]  F. Breviario,et al.  Enhancement by interleukin-1 (IL-1) of plasminogen activator inhibitor (PA-I) activity in cultured human endothelial cells. , 1986, Biochemical and biophysical research communications.

[16]  K. Hajjar,et al.  Interleukin 1 induces endothelial cell synthesis of plasminogen activator inhibitor , 1986, The Journal of experimental medicine.

[17]  T. Kooistra,et al.  Interleukin 1 and lipopolysaccharide induce an inhibitor of tissue-type plasminogen activator in vivo and in cultured endothelial cells , 1986, The Journal of experimental medicine.

[18]  P. Miossec,et al.  Production of interleukin 1 by human endothelial cells. , 1986, Journal of immunology.

[19]  D. Monard,et al.  A glia‐derived neurite‐promoting factor with protease inhibitory activity. , 1985, The EMBO journal.

[20]  W. Fierz,et al.  Astrocytes as antigen-presenting cells. I. Induction of Ia antigen expression on astrocytes by T cells via immune interferon and its effect on antigen presentation. , 1985, Journal of immunology.

[21]  R. McCarron,et al.  Presentation of myelin basic protein by murine cerebral vascular endothelial cells. , 1985, Journal of immunology.

[22]  G. Moonen,et al.  Plasminogen activator is a mitogen for astrocytes in developing cerebellum. , 1985, Brain research.

[23]  L. Lachman,et al.  Interleukin-1 stimulation of astroglial proliferation after brain injury. , 1985, Science.

[24]  J. Merrill,et al.  Proliferation of astroglia and oligodendroglia in response to human T cell-derived factors. , 1984, Science.

[25]  W. Fierz,et al.  Astrocytes present myelin basic protein to encephalitogenic T-cell lines , 1984, Nature.

[26]  A. Fontana,et al.  Production of prostaglandin E and an interleukin-1 like factor by cultured astrocytes and C6 glioma cells. , 1982, Journal of immunology.

[27]  G. Moonen,et al.  Plasminogen activator–plasmin system and neuronal migration , 1982, Nature.

[28]  H. Kleinman,et al.  Fibronectin promotes rat Schwann cell growth and motility , 1982, The Journal of cell biology.

[29]  M. Raff,et al.  Studies on cultured rat Schwann cells. I. Establishment of purified populations from cultures of peripheral nerve , 1979, Brain Research.

[30]  J. Vassalli,et al.  Macrophage plasminogen activator: induction by products of activated lymphoid cells , 1977, The Journal of experimental medicine.

[31]  L. Greene,et al.  Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. , 1976, Proceedings of the National Academy of Sciences of the United States of America.

[32]  M. M. Bradford.  A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. , 1976, Analytical biochemistry.

[33]  U. K. Laemmli,et al.  Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4 , 1970, Nature.

[34]  W. W. Nichols,et al.  Definition of a continuous human cell line derived from neuroblastoma. , 1970, Cancer research.

[35]  M. Nieto‐Sampedro,et al.  Interleukin‐1‐like activity in rat brain: Sources, targets, and effects of injury , 1987, Journal of neuroscience research.

[36]  H. Thoenen,et al.  Interleukin-1 regulates synthesis of nerve growth factor in non-neuronal cells of rat sciatic nerve , 1987, Nature.

[37]  H. Wekerle,et al.  Antigen presentation in the peripheral nervous system: Schwann cells present endogenous myelin autoantigens to lymphocytes , 1986, European journal of immunology.

[38]  M. De Ley,et al.  Homogeneous interferon-inducing 22K factor is related to endogenous pyrogen and interleukin-1 , 1985, Nature.

[39]  G H Sato,et al.  Growth of a rat neuroblastoma cell line in serum-free supplemented medium. , 1979, Proceedings of the National Academy of Sciences of the United States of America.

[40]  J. Booher,et al.  Growth and cultivation of dissociated neurons and glial cells from embryonic chick, rat and human brain in flask cultures. , 1972, Neurobiology.