Mice lacking the signaling molecule CalDAG-GEFI represent a model for leukocyte adhesion deficiency type III.
暂无分享,去创建一个
Ann M Graybiel | A. Graybiel | D. Housman | D. Wagner | Hong-wei Wang | J. Crittenden | W. Bergmeier | Wolfgang Bergmeier | Jill R Crittenden | T. Goerge | Denisa D Wagner | Hong-Wei Wang | David E Housman | Stephen M Cifuni | Tobias Goerge | Andrew C W Baldwin | S. Cifuni | A. C. Baldwin
[1] Richard O Hynes,et al. Susceptibility to Infection and Altered Hematopoiesis in Mice Deficient in Both P- and E-Selectins , 1996, Cell.
[2] E. Engvall,et al. Blood Platelets Contain and Secrete Laminin-8 (α4β1γ1) and Adhere to Laminin-8 via α6β1 Integrin , 1999 .
[3] N. Hogg,et al. The Use of Lymphocyte Function–Associated Antigen (Lfa)-1–Deficient Mice to Determine the Role of Lfa-1, Mac-1, and α4 Integrin in the Inflammatory Response of Neutrophils , 2001, The Journal of experimental medicine.
[4] R. Adams,et al. A novel syndrome of variant leukocyte adhesion deficiency involving defects in adhesion mediated by beta1 and beta2 integrins. , 2001, Blood.
[5] S. Orkin,et al. Association of a Ras-related protein with cytochrome b of human neutrophils , 1989, Nature.
[6] A. Graybiel,et al. A Rap guanine nucleotide exchange factor enriched highly in the basal ganglia. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[7] J. Bos,et al. Rap1 signalling: adhering to new models , 2001, Nature Reviews Molecular Cell Biology.
[8] Contribution of LFA-1 and Mac-1 to CD18-dependent neutrophil emigration in a neonatal rabbit model. , 1996, Journal of applied physiology.
[9] Thomas N. Sato,et al. Persistence of platelet thrombus formation in arterioles of mice lacking both von Willebrand factor and fibrinogen. , 2000, The Journal of clinical investigation.
[10] D. Spriggs,et al. Non‐kinase second‐messenger signaling: new pathways with new promise , 2004, BioEssays : news and reviews in molecular, cellular and developmental biology.
[11] T. Mayadas,et al. Leukocyte rolling and extravasation are severely compromised in P selectin-deficient mice , 1993, Cell.
[12] R. V. van Lier,et al. Leukocyte adhesion deficiency type 1 (LAD-1)/variant. A novel immunodeficiency syndrome characterized by dysfunctional beta2 integrins. , 1997, The Journal of clinical investigation.
[13] A. Graybiel,et al. CalDAG-GEFI integrates signaling for platelet aggregation and thrombus formation , 2004, Nature Medicine.
[14] S. Russell,et al. Generation and rescue of a murine model of platelet dysfunction: the Bernard-Soulier syndrome. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[15] S. Dedhar,et al. Integrin-linked kinase (ILK) and its interactors , 2001, The Journal of cell biology.
[16] E. Caron. Cellular functions of the Rap1 GTP-binding protein: a pattern emerges , 2003, Journal of Cell Science.
[17] Zaverio M. Ruggeri,et al. Platelets in atherothrombosis , 2002, Nature Medicine.
[18] E. Butcher. Leukocyte-endothelial cell recognition: Three (or more) steps to specificity and diversity , 1991, Cell.
[19] R. Alon,et al. LAD-III, a novel group of leukocyte integrin activation deficiencies. , 2003, Trends in immunology.
[20] A. Beaudet,et al. Neutrophil Emigration in the Skin, Lungs, and Peritoneum: Different Requirements for CD11/CD18 Revealed by CD18-deficient Mice , 1997, The Journal of experimental medicine.
[21] G. Bokoch,et al. Purification and characterization of Rac 2. A cytosolic GTP-binding protein that regulates human neutrophil NADPH oxidase. , 1992, The Journal of biological chemistry.
[22] Nigel Klein,et al. A novel form of integrin dysfunction involving β1, β2, and β3 integrins , 2003 .
[23] M. Ginsberg,et al. Integrin activation by talin , 2005, Journal of thrombosis and haemostasis : JTH.
[24] S. Kunapuli,et al. Protein kinase C- and calcium-regulated pathways independently synergize with Gi pathways in agonist-induced fibrinogen receptor activation. , 2002, The Biochemical journal.
[25] M. Ginsberg,et al. Integrin cytoplasmic domain-binding proteins. , 2000, Journal of cell science.
[26] A. Graybiel,et al. The small GTPase Rap1b regulates the cross talk between platelet integrin α2β1 and integrin αIIbβ3 , 2006 .
[27] B. Savage,et al. Mechanisms of platelet aggregation. , 2001, Current opinion in hematology.
[28] S. Simon,et al. Molecular mechanics and dynamics of leukocyte recruitment during inflammation. , 2005, Annual review of biomedical engineering.
[29] U. V. von Andrian,et al. Bltr Mediates Leukotriene B4–Induced Chemotaxis and Adhesion and Plays a Dominant Role in Eosinophil Accumulation in a Murine Model of Peritonitis , 2000, The Journal of experimental medicine.
[30] B. Nieswandt,et al. Multiple integrin-ligand interactions synergize in shear-resistant platelet adhesion at sites of arterial injury in vivo. , 2003, Blood.
[31] B. Nieswandt,et al. Flow cytometric detection of activated mouse integrin αIIbβ3 with a novel monoclonal antibody , 2002 .
[32] R. Hynes,et al. A mouse model of severe von Willebrand disease: defects in hemostasis and thrombosis. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[33] J. Sixma,et al. Platelet adhesion to fibronectin in flow: dependence on surface concentration and shear rate, role of platelet membrane glycoproteins GP IIb/IIIa and VLA-5, and inhibition by heparin. , 1994, Blood.
[34] T. Springer,et al. Leukocyte adhesion deficiency: an inherited defect in the Mac-1, LFA-1, and p150,95 glycoproteins. , 1987, Annual review of medicine.
[35] T. Ugarova,et al. Recognition of Fibrinogen by Leukocyte Integrins , 2001, Annals of the New York Academy of Sciences.
[36] Y. Tomiyama. Glanzmann thrombasthenia: integrin alpha IIb beta 3 deficiency. , 2000, International journal of hematology.
[37] D. Priebat,et al. Measurement of cutaneous inflammation: estimation of neutrophil content with an enzyme marker. , 1982, The Journal of investigative dermatology.
[38] J. Bos,et al. The role of Rap1 in integrin-mediated cell adhesion. , 2001, Biochemical Society transactions.
[39] Richard O Hynes,et al. Integrins Bidirectional, Allosteric Signaling Machines , 2002, Cell.
[40] R. Hynes,et al. Beta3-integrin-deficient mice are a model for Glanzmann thrombasthenia showing placental defects and reduced survival. , 1999, The Journal of clinical investigation.
[41] S Askari,et al. A novel role for the beta 2 integrin CD11b/CD18 in neutrophil apoptosis: a homeostatic mechanism in inflammation. , 1996, Immunity.
[42] Amos Etzioni,et al. LAD-III, a leukocyte adhesion deficiency syndrome associated with defective Rap1 activation and impaired stabilization of integrin bonds. , 2004, Blood.
[43] D. Staunton,et al. A novel genetic leukocyte adhesion deficiency in subsecond triggering of integrin avidity by endothelial chemokines results in impaired leukocyte arrest on vascular endothelium under shear flow. , 2003, Blood.
[44] W. Kolanus,et al. Regulation of integrin function by inside-out signaling mechanisms. , 1998, Current topics in microbiology and immunology.
[45] A. Abo,et al. Activation of the NADPH oxidase involves the small GTP-binding protein p21rac1 , 1991, Nature.
[46] A Etzioni,et al. Leukocyte Adhesion Deficiency Type II is a generalized defect of de novo GDP-fucose biosynthesis. Endothelial cell fucosylation is not required for neutrophil rolling on human nonlymphoid endothelium. , 1998, The Journal of clinical investigation.
[47] T. Fischer,et al. Rap1b is required for normal platelet function and hemostasis in mice. , 2005, The Journal of clinical investigation.
[48] P. Gaehtgens,et al. Impairment of neutrophil emigration in CD18-null mice. , 1999, American journal of physiology. Gastrointestinal and liver physiology.
[49] Michael Loran Dustin,et al. The immunological synapse: integrins take the stage , 2002, Immunological reviews.
[50] T. Kuijpers,et al. Leukocyte adhesion deficiency-type 1 (LAD-1)/variant: A novel immunodeficiency syndrome characterized by dysfunctional β2 integrins , 1997 .
[51] E. Lapetina,et al. Structure and Function of rap Proteins in Human Platelets , 1994, Thrombosis and Haemostasis.
[52] K. Ley,et al. Severely reduced neutrophil adhesion and impaired host defense against fecal and commensal bacteria in CD18–/–P‐selectin–/–double null mice , 2002, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.